The role of lipid metabolism in neuronal senescence
FEBS Open Bio, Volume 16, Issue 5, Page 857-869, May 2026.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Effect of dietary supplementation of alpha-galactosidase on the growth performance, ileal digestibility, intestinal morphology, and biochemical parameters in broiler chickens. [PDF]
BMC Vet Res, 2020 Amer SA +6 more
europepmc +1 more source
Advanced Science, Volume 13, Issue 26, 8 May 2026.Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen +16 more
wiley +1 more source
Spatial regulation of alpha-galactosidase activity and its influence on raffinose family oligosaccharides during seed maturation and germination in Cicer arietinum. [PDF]
Plant Signal Behav, 2020 Arunraj R +6 more
europepmc +1 more source
Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response
Advanced Science, Volume 13, Issue 26, 8 May 2026.This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai +7 more
wiley +1 more source
Correlation between GLA variants and alpha-Galactosidase A profile in dried blood spot: an observational study in Brazilian patients. [PDF]
Orphanet J Rare Dis, 2020 Varela P +13 more
europepmc +1 more source
Food Frontiers, Volume 7, Issue 3, May 2026.ABSTRACT Ergothioneine (EGT), a natural thiol derivative, has gained attention as a geroprotective nutraceutical. Preclinical research shows EGT scavenges free radicals, maintains mitochondrial integrity, slows telomere erosion, and regulates proteostasis via autophagy and senescent cell clearance.
Tian‐Tian Tian +3 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 5, May 2026.Protocatechuic acid attenuates D‐gal‐induced renal aging through regulation of CSAD‐mediated taurine metabolism, thereby alleviating oxidative stress and inflammation. ABSTRACT Protocatechuic acid (PCA), a natural phenolic compound with antioxidant and anti‐inflammatory properties, has been proposed as a potential therapeutic agent against aging ...
Songhao Tian +6 more
wiley +1 more source
Correction: Serological Assessment of Alpha Galactosidase, N-Glycolylneuraminic Acid, and Histopathological Observations in Xenograft Recipients. [PDF]
CureusRamesh B +3 more
europepmc +1 more source