Results 161 to 170 of about 900,860 (290)

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

Mutations of alpha-galactosidase A gene in two unusual cases of Fabry disease

, 1999
The mutation analysis of alpha-galactosidase A gene was carried out in two families with Fabry disease described by us earlier. In the family P. a new point mutation E341K (a G to A transition at position 10999 of the gene) was identified.
Van Amstel, JKP, Kopishinskaya, SV, Beyer, EM, Tsvetkova, [No Value]   +3 more
core  

Hypoxia‐inducible factor‐1a (HIF1a) as a context‐dependent integrator of metabolic stress in skeletal muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Hypoxia‐inducible factor‐1a (HIF1a) integrates physiological and pathological inputs in skeletal muscle, including exercise, circadian timing, cytotoxins and disease. These inputs alter mitochondrial oxidative function, redox state, reactive oxygen species, and local oxygen availability, leading to intermittent or sustained HIF1a
Nicole Welch, Pugazhendhi Kannan, Seshu Vardhan Pothabathula, Annette Bellar, Abhishek A. Chakraborty, Saurabh Mishra, Srinivasan Dasarathy   +6 more
wiley   +1 more source

Pegunigalsidase alfa: a novel, pegylated recombinant alpha-galactosidase enzyme for the treatment of Fabry disease. [PDF]

Front Genet
Germain DP, Linhart A.
europepmc   +1 more source

Preharvest supplemental lighting enhances productivity and modulates postharvest quality in hydroponically grown Apulian unripe melon ‘Scopatizzo’ ( Cucumis melo L.)

Journal of the Science of Food and Agriculture, Volume 106, Issue 13, Page 7666-7681, October 2026.
Abstract BACKGROUND Preharvest light management is increasingly used to enhance yield and fruit quality in soilless systems, yet its effects on unripe melon fruits remain poorly understood. This study evaluated the impact of supplemental red–blue light‐emitting diode (LED) lighting applied during cultivation in a closed‐cycle hydroponic system on ...
Onofrio Davide Palmitessa, Marica Troilo, Carlo Porfido, Roberto Terzano, Davide De Angelis, Massimiliano Renna, Francesco Caponio, Pietro Santamaria   +7 more
wiley   +1 more source

Enfermedad de Fabry, a propósito de un caso interesante

Revista Médica Electrónica
La enfermedad de Fabry es una enfermedad por almacenamiento lisosómico hereditaria ligada al cromosoma X, y se deriva de mutaciones en el gen que codifica la enzima alfa-galactosidasa.
Irelys González López, Enrique Marcos Sierra Benítez, Mairiannys Quianella León Pérez, Carlos Emilio Díaz Domínguez, Maylin Rodríguez Delgado, Yunaisy Pérez Sánchez   +5 more
doaj  

Safety and efficacy of a feed additive consisting of alpha-galactosidase (produced with <i>Aspergillus tubingensis</i>ATCC SD 6740) and endo-1,4-beta-xylanase (produced with <i>Trichoderma orientale</i>CBS 139997) (Capsozyme SB Plus) for turkeys for fattening and reared for breeding (Industrial Técnica Pecuaria, S.A.). [PDF]

EFSA J
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Dusemund B, Gehring R, Glandorf B, Kouba M, López-Alonso M, Marcon F, Nebbia C, Pechová A, Prieto-Maradona M, Röhe I, Theodoridou K, Brantom P, Anguita M, Galobart J, L Innocenti M, Pettenati E, Pizzo F, Brozzi R.   +23 more
europepmc   +1 more source

Junctional Adhesion Molecule‐A (JAM‐A) Associates With High‐Risk Disease in Multiple Myeloma Patients and a Structure‐Based Rationally‐Designed Peptide Inhibitor Attenuates Tumorigenic Features In Vitro and In Vivo

European Journal of Haematology, Volume 117, Issue 4, Page 995-1006, October 2026.
ABSTRACT Multiple myeloma (MM) is an incurable malignancy of terminally‐differentiated plasma cells that represents a major clinical challenge despite unprecedented therapeutic advances, particularly for patients with cytogenetically‐defined high‐risk MM (HR‐MM).
Niamh McAuley, Roisin McAvera, Dimitri Bong, Lara Donnelly, Izabela Cymer, Marian Brennan, Joanna Fay, Lance Hudson, John Quinn, Siobhan V. Glavey, Ann M. Hopkins   +10 more
wiley   +1 more source

Enzyme@Silicone: A Versatile Combo for Robust Synthetic Biocatalysis?

Advanced Synthesis &Catalysis, Volume 368, Issue 17, 1 September 2026.
Silicone‐based polymers are versatile materials for enzyme immobilization, offering unique advantages such as chemical inertness, thermal stability, and tunable morphology. This review highlights their applications in synthetic biocatalysis, from batch to continuous processes, and addresses key challenges such as mass transport limitations and ...
Marion B. Ansorge‐Schumacher
wiley   +1 more source