Results 171 to 180 of about 954,264 (289)

Preclinical efficacy and safety of adeno-associated virus 5 alpha-galactosidase: A gene therapy for Fabry disease. [PDF]

Mol Ther Methods Clin Dev
Liefhebber JMP, Brasser G, Spronck EA, Ottenhoff R, Paerels L, Ferraz MJ, Schwarz LK, Efthymiopoulou N, Kuo CL, Montenegro-Miranda PS, Evers MM, Aerts JMFG, Liu YP.   +12 more
europepmc   +1 more source

The Effect of pH Changes on the Levels of Alpha-Galactosidase A in a Patient with Fabry's Disease, Post Renal Transplant

, 1989
Fabry's disease (alpha-galactosidase A deficiency) leads to early renal failure. Unfortunately, kidney transplants do not always reliably supply the deficient enzyme. To assess urinary and serum activity of alpha-galactosidase A by the transplant as well
Brown, Lois E.
core  

Structural insights into xyloglucan recognition by an ABC transporter from a Gram‐positive, thermophilic bacterium

The FEBS Journal, EarlyView.
Athe_2052 is an ABC transporter substrate‐binding protein that recognizes xyloglucan heptasaccharide (XXXG), a soluble breakdown product of plant xyloglucan. The crystal structure of Athe_2052, together with binding assays and computational modeling, shows how XXXG is recognized by this sugar transporter.
Hansen Tjo, Virginia Jiang, Philip D. Jeffrey, Angela Zhu, A. James Link, Jerelle A. Joseph, Jonathan M. Conway   +6 more
wiley   +1 more source

Serum Agalactosyl IgG Predicts Hepatocellular Carcinoma and All‐Cause Mortality After SVR in Advanced Chronic Hepatitis C

Hepatology Research, EarlyView.
ABSTRACT Background and Aims Patients with chronic hepatitis C and advanced fibrosis remain at substantial risk of hepatocellular carcinoma (HCC) and non‐liver–related death even after sustained virological response (SVR) to direct‐acting antivirals (DAA).
Daisuke Sakon, Jumpei Kondo, Yuki Tahata, Hayato Hikita, Maki Iwaisako, Muya Matsumoto, Asuka Ogata, Shinji Takamatsu, Yasutoshi Nozaki, Naruyasu Kakita, Hisashi Ishida, Fumihiko Nakanishi, Yuichi Yoshida, Masanori Nakahara, Kazuho Imanaka, Mitsuru Sakakibara, Takayuki Yakushijin, Tetsuo Takehara, Takahiro Kodama, Eiji Miyoshi   +19 more
wiley   +1 more source

Pegunigalsidase alfa: a novel, pegylated recombinant alpha-galactosidase enzyme for the treatment of Fabry disease. [PDF]

Front Genet
Germain DP, Linhart A.
europepmc   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

International Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Enfermedad de Fabry, a propósito de un caso interesante

Revista Médica Electrónica
La enfermedad de Fabry es una enfermedad por almacenamiento lisosómico hereditaria ligada al cromosoma X, y se deriva de mutaciones en el gen que codifica la enzima alfa-galactosidasa.
Irelys González López, Enrique Marcos Sierra Benítez, Mairiannys Quianella León Pérez, Carlos Emilio Díaz Domínguez, Maylin Rodríguez Delgado, Yunaisy Pérez Sánchez   +5 more
doaj  

Purification, characterization, and hydrolytic activity of alpha-galactosidase from Lactobacillus helveticus ATCC 10797

, 2006
In this study, alpha-Galactosidase (alpha-D-galactoside-galactohydrolase, EC 3.2.1.22) has been isolated, purified, and characterized from intracellular fraction of Lactobacillus helveticus ATCC 10797. It was purified by a combination of ammonium sulfate
Al-kandari, Sharifa.
core  

Integrated chemical profiling, transcriptomics and functional validation elucidate the multifunctional benefits of a triple‐ferment filtrate complex for skin aging intervention

International Journal of Cosmetic Science, EarlyView.
Integrated chemical profiling, transcriptomics and functional validation reveal the multifunctional benefits of a triple‐ferment filtrate complex for skin aging intervention. Abstract Objective Skin aging is driven by interconnected hallmarks including oxidative stress and chronic low‐grade inflammation, cellular senescence, impaired epidermal function
Ping Gao, Xue Xiao, Hong Zhang, Fengjuan Tu, Xuelan Gu   +4 more
wiley   +1 more source