Results 171 to 180 of about 118,748,616 (241)

Integrated chemical profiling, transcriptomics and functional validation elucidate the multifunctional benefits of a triple‐ferment filtrate complex for skin aging intervention

International Journal of Cosmetic Science, EarlyView.
Integrated chemical profiling, transcriptomics and functional validation reveal the multifunctional benefits of a triple‐ferment filtrate complex for skin aging intervention. Abstract Objective Skin aging is driven by interconnected hallmarks including oxidative stress and chronic low‐grade inflammation, cellular senescence, impaired epidermal function
Ping Gao, Xue Xiao, Hong Zhang, Fengjuan Tu, Xuelan Gu   +4 more
wiley   +1 more source

Diagnosis of Fabry Disease Using Alpha-Galactosidase A Activity or LysoGb3 in Blood Fails to Identify Up to Two Thirds of Female Patients. [PDF]

Int J Mol Sci
Duro G, Anania M, Zizzo C, Francofonte D, Giacalone I, D'Errico A, Marsana EM, Colomba P.   +7 more
europepmc   +1 more source

Challenging popular tools for the annotation of genetic variations with a real case, pathogenic mutations of lysosomal alpha-galactosidase. [PDF]

BMC Bioinformatics, 2018
Cimmaruta C, Citro V, Andreotti G, Liguori L, Cubellis MV, Hay Mele B.   +5 more
europepmc   +1 more source

S‑glutathionylation of MaWRKY44 orchestrates a MaZFP139‐MaWRKY44‐MaGSTU07 cascade to enhance banana cold tolerance

Journal of Integrative Plant Biology, EarlyView.
In banana, at low temperatures (7°C), the transcription factor MaZFP139 activates MaWRKY44 expression. MaWRKY44 binds to the W‐box sites in the promoter of the glutathione S‐transferase gene MaGSTU07 to enhance reactive oxygen species scavenging. S‐glutathionylation protects MaWRKY44 from oxidation‐induced degradation, reinforcing antioxidant defenses ...
Shuqin Lin, Wen Song, Shaoting Liao, Haike Tan, Jianji Qi, Danling Cai, Wei Wei, Wei Shan, Jianfei Kuang, Jianye Chen, Wangjin Lu   +10 more
wiley   +1 more source

Clinical impact of the alpha-galactosidase A gene single nucleotide polymorphism -10C>T: A single-center observational study. [PDF]

Medicine (Baltimore), 2018
Oder D, Liu D, Üçeyler N, Sommer C, Hu K, Salinger T, Müntze J, Petritsch B, Ertl G, Wanner C, Nordbeck P, Weidemann F.   +11 more
europepmc   +1 more source

Phloridzin Mitigates Aging‐Associated Periodontitis by Restraining Inflammatory Cell Death

Journal of Periodontal Research, EarlyView.
Phloridzin attenuated oxidative stressinduced senescence, inflammatory responses, and osteogenic dysfunction in HPDLCs. In an aging‐associated experimental periodontitis model, phloridzin alleviated alveolar bone loss, suggesting its potential to maintain periodontal tissue integrity under aging‐related inflammatory conditions.
Da Eun Lee, Eun‐Nam Kim, Gil‐Saeng Jeong   +2 more
wiley   +1 more source

Archaeal Genes Code for GGDEF Domain Proteins With Diguanylate Cyclase Activity

Molecular Microbiology, EarlyView.
A biofilm‐like mode of growth is hypothesized to be required for the emergence of cellular life. Occurrence of common biofilm gene products in current Bacteria and Archaea is an indication for their previous presence in the last universal common ancestor LUCA and perhaps even in the first universal common ancestor FUCA.
Roman Sidorov, Li Li, Ali Dadvar, Irfan Ahmad, Stefan Spring, Jörg Overmann, Ute Römling   +6 more
wiley   +1 more source

Affective and cognitive behavior in the alpha-galactosidase A deficient mouse model of Fabry disease. [PDF]

PLoS One, 2017
Hofmann L, Karl F, Sommer C, Üçeyler N.   +3 more
europepmc   +1 more source

Topological, Functional, and Phylogenetic Analysis of the Cell Division Site Selection Protein MinJ of Bacillus subtilis

Molecular Microbiology, EarlyView.
MinJ is a nine‐pass transmembrane protein with a cytoplasmic PDZ domain. The PDZ domain, while required for division, is dispensable for localization, and deletion of the transmembrane segments 6 and 7 results in a hyper‐minicell phenotype. ABSTRACT The Min system disassembles FtsZ‐rings after septation in Bacillus subtilis and is localized to the ...
Kehinde O. Adebiyi, Laura C. Lastra, Jane H. Joncha, Sadie B. Ruesewald, Stephen C. Jacobson, Daniel B. Kearns   +5 more
wiley   +1 more source

Comparative genomics of dark septate endophytes: shedding light on the enigmatic lifestyle and biology of DSEs

New Phytologist, EarlyView.
Ancestral lifestyle reconstruction across the phylogeny of the 107 analysed fungal genomes. Summary Dark septate endophytes (DSE) are widespread root‐colonising fungi with poorly understood lifestyle and ecological functions. We investigated their genomic traits, sexual reproduction signatures, carbohydrate‐active enzyme (CAZyme) and secondary ...
Sándor Csíkos, Zsolt Merényi, Dániel G. Knapp, Anna Lipzen, Kurt LaButti, Jasmyn Pangilinan, Robert Riley, Sajeet Haridas, Asaf Salamov, Kerrie Barry, Alan Kuo, Elodie Drula, Igor V. Grigoriev, Bernard Henrissat, Francis Martin, László G. Nagy, Gábor M. Kovács   +16 more
wiley   +1 more source