Results 161 to 170 of about 286,880 (314)

Tolerance to Phosphorus Deficiency Improves Seed Phytic Acid‐to‐Iron Molar Ratios in Common Bean

Plant, Cell &Environment, EarlyView.
ABSTRACT Although significant advances have been achieved in the biofortification of common beans to overcome deficiencies in Zinc (Zn) and iron (Fe), the mechanisms involved remain poorly understood. We thus explored the relationships between phosphorus nutrition and Zn and Fe accumulation in four bean genotypes (Edar, Nizok, Colorado and Chimbolos ...
Barbara Karpinska, Christine H. Foyer
wiley   +1 more source

Reviewing the benefits and clinical outcomes of oral fibroblasts over mesenchymal stem cells for repairing periodontal defects during or after orthodontic tooth movement

Periodontology 2000, EarlyView.
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi, Eleni Mavrogonatou, Anton Sculean, Dimitris Kletsas, Martin Degen   +4 more
wiley   +1 more source

Expert review in diagnostic, therapeutic and follow-up of Fabry disease in Latin America based on patient care standards

Molecular Genetics and Metabolism Reports
Background: Fabry disease (FD) is an X-linked lysosomal sphingolipidosis. It is caused by pathogenic variants in the GLA gene with a consequent deficiency of the enzyme α-galactosidase A, resulting in the pathological accumulation of glycolipids - mainly
Roberto Giugliani, Juan Politei, Ana Martins, Nelson Murillo, Paula Rozenfeld, Mauricio Lopera, Sergio Salgado, Gustavo Quirós, Charles Marques Lourenço, Osvaldo Vieira, Hernán Amartino, Fernando Perretta, Sandra Marques e Silva, Joseph Brooks, Laura Titievsky, Jacobo Villalobos, Cassiano Braga, Harris A. Peñaranda   +17 more
doaj   +1 more source

Characterization of Sirt2 using conditional RNAi in mice [PDF]

, 2011
Within the past eight years, RNA interference (RNAi) has emerged as a powerful experimental tool for gene function analysis in mice. Reversible control of shRNA mediated RNAi has been achieved by using a tetracycline (tet)-inducible promoter.
Reiss, Martina
core  

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

Pitfalls and missing links in current understanding of 4D genomes

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The spatial and temporal organization of the genome—collectively termed the 4D genome—is pivotal for regulating gene expression, maintaining genome stability, and guiding development. The convergence of chromosome conformation capture technologies, super‐resolution microscopy, and single‐cell epigenomics has transformed our understanding of ...
Michael Q. Zhang
wiley   +1 more source

Traversing the effects of ploidy changes in different Eragrostis curvula genotypes through high‐throughput RNA sequencing

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Polyploidization has played a key role in plant genome evolution. Eragrostis curvula (Schrad.) Ness, a perennial forage grass species of the Poaceae family, is an excellent model for investigating genome duplication due to its natural variation in ploidy levels.
D. F. Santoro, J. Carballo, M. C. Pasten, C. A. Gallo, E. Albertini, V. Echenique   +5 more
wiley   +1 more source

The alpha-galactosidase A p.Arg118Cys variant does not cause a Fabry disease phenotype: data from individual patients and family studies.

Molecular Genetics and Metabolism, 2015
Susana Ferreira, A. Ortiz, D. Germain, M. Viana-Baptista, António Caldeira-Gomes, M. Campreciós, M. Fenollar-Cortés, Ángel Gallegos-Villalobos, Diego García, J. García-Robles, J. Egido, E. Gutiérrez‐Rivas, J. Herrero, Sebastián Mas, Raluca Oancea, Paloma Péres, Luis Manuel Salazar-Martín, J. Solera-García, H. Alves, S. Garman, J. Oliveira   +20 more
semanticscholar   +1 more source

The Recycling Endosomal (Na+, K+)/H+ Exchanger NHE6/SLC9A6 Facilitates Signal Transduction by Shuttling Cyclin‐Dependent Kinase 5 to the Plasma Membrane

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim The alkali cation/proton exchanger NHE6/SLC9A6 regulates luminal pH homeostasis and trafficking of recycling endosomes in most tissues, especially neurons. Loss‐of‐function mutations in NHE6 cause Christianson Syndrome, an X‐linked neurodevelopmental and neurodegenerative disorder; however, the underlying molecular and cellular mechanisms ...
Rebecca Flessner, Alina Ilie, Léo Han, Annie Boucher, Rebecca Anne McKinney, Reza Sharif‐Naeini, John Orlowski   +6 more
wiley   +1 more source

Annona muricata (graviola): toxic or therapeutic [PDF]

, 2008
This paper examines annona muricata (graviola): toxic or ...
Gray, A.I., Hollinshead, J., Jones, L., Jones, P.W., Mohanty, S., Thomas, D., Watson, A.A., Watson, D.G.   +7 more
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