Results 91 to 100 of about 46,608 (304)

Evaluation of Antidiabetic Activity of Croton zambesicus Root Extract: In Vivo Inhibitory Effect on Alpha Amylase and Alpha Glucosidase of Rats

Biology, Medicine & Natural Product Chemistry
Diabetes mellitus is a global health challenge, necessitating the need for alternative treatments. Croton zambesicus Muell Arg. (Euphorbiaceace) a medicinal plant used traditionally in the treatment of some ailments was investigated for its inhibitory ...
Jude Efiom Okokon, Utibe Anietie Edem, Chinyelu Clementina OSIGWE, Ugonma Florence Uwaeme   +3 more
doaj   +1 more source

Phytochemical Screening and Antihyperglycaemic Activities of Cordyceps Sinensis and Its Based Product (esulin) [PDF]

, 2016
Diabetes mellitus merupakan satu gangguan metabolik umum dengan komplikasi vascular mikro dan makro yang mengakibatkan morbiditi dan kematian yang ketara.
Ab Rahman, Farah ‘Atiqah
core  

Nutraceutical Evaluation of Biscuits Formulated From Acha, Chia, and Soycake Flours on Glycemic Control, Lipid Profile, and Histopathological Effects in High‐Fat Diet/Streptozotocin‐Induced Type 2 Diabetic Rats

Food Chemistry International, EarlyView.
Acha–chia–soycake biscuits improved glucose tolerance, lipid profile, insulin levels, and pancreatic integrity in HFD–STZ diabetic rats. ACSB1 and ACSB13 outperformed acarbose, showing potent antihyperglycemic, hypolipidemic, and pancreatic‐protective effects.
Oluwafunmilayo Christianah Ogunnowo, Olufunmilayo Sade Omoba, Aderonke Ibidunni Olagunju, Olamide Wilson Fasakin, Idowu Sunday Oyeleye, Olajide Raymond Ojo   +5 more
wiley   +1 more source

A New Vista of Opportunity in Diabetes Management: Natural Product‐Based β‐cell Preservation

Food Chemistry International, EarlyView.
Preserving functional β‐cells via natural products offers promising strategy for diabetes treatment. ABSTRACT A defining characteristic of diabetes is β‐cell failure, in which β‐cells cannot modulate insulin secretion to compensate for escalating insulin resistance, pushing forward disease development.
Yi‐San Lee, Tien‐Fen Kuo, Chun‐Yen Yang, Greta Yang, Wen‐Chin Yang   +4 more
wiley   +1 more source

Clinical guidelines for late-onset Pompe disease [PDF]

, 2012
English version available at www.neurologia.comHasta 2006, la enfermedad de Pompe o glucogenosis tipo II era una enfermedad incurable y con tratamiento meramente paliativo.
Barba-Romero, Miguel A., Barrot, Emilia, Bautista-Lorite, Juan, Gutiérrez-Rivas, Eduardo, Illa, Isabel, Jiménez, Luis M., Ley-Martos, Myriam, López de Munain, Adolfo, Pardo, Julio, Pascual-Pascual, S. I., Pérez-López, Jordi, Solera, Jesús, Vílchez-Padilla, Juan J.   +12 more
core   +1 more source

Nutritional, Functional, and Anti‐Hypercholesterolemic Properties of Sourdough Breads From Unripe Plantain, Tiger Nut, and Fenugreek Flours

Food Chemistry International, EarlyView.
Composite sourdough breads were developed from blends of unripe plantain, tiger nut, and fenugreek flours. Optimized formulations improved pasting stability and enhanced texture, producing softer more elastic crumbs. The enriched breads contained higher dietary fiber and bioactive compounds, and significantly reduced serum cholesterol markers ...
Mary T. Ademosun, Olufunmilayo S. Omoba, Ganiyu Oboh, Adedamola I. Akinyede, Rukayat O. Awolola   +4 more
wiley   +1 more source

CRIM-negative infantile Pompe disease: 42-month treatment outcome [PDF]

, 2018
Pompe disease is a rare lysosomal glycogen storage disorder characterized by deficiency of acid α-glucosidase enzyme (GAA) and caused by mutations in the GAA gene.
Balmer, Christian, Baumgartner, Matthias, Klein, Andrea, Köhli-Wiesner, Alice, Lauener, Roger, Rohrbach, Marianne, Scheer, Ianina, Veraguth, Dorothe   +7 more
core  

Impact of enzyme replacement therapy on survival in adults with Pompe disease: Results from a prospective international observational study [PDF]

, 2013
Background: Pompe disease is a rare metabolic myopathy for which disease-specific enzyme replacement therapy (ERT) has been available since 2006. ERT has shown efficacy concerning muscle strength and pulmonary function in adult patients. However, no data
D'Agostino, R.B. (Ralph), Doorn, P.A. (Pieter) van, Güngör, D. (Deniz), Hagemans, M.L.C. (Marloes), Kruijshaar, M.E. (Michelle), Ploeg, A.T. (Ans) van der, Plug, I. (Iris), Reuser, A.J.J. (Arnold)   +7 more
core   +1 more source

Potential of Bee Pollen as a Nutraceutical And/Or Functional Ingredient for Metabolic Syndrome Management: In Vitro Antioxidant, Anti‐Inflammatory, and Digestive Enzyme Inhibitory Activities

Food Chemistry International, EarlyView.
Bee pollen samples from China and Spain exhibited in vitro antioxidant, anti‐inflammatory, and digestive enzyme inhibitory activities due to their composition, suggesting their potential as a nutraceutical or functional ingredient to help counteract oxidative stress, chronic inflammation, and metabolic disorders.
Adriana Maite Fernández‐Fernández, Victoria Olt, Jessica Báez, Marcelo Miraballes, Melissa Romero, Cecilia Dauber, Ignacio Vieitez, Estela Santos, Adriana Gámbaro, Alejandra Medrano   +9 more
wiley   +1 more source

Anti-Diabetic Activity of 2,3,6-Tribromo-4,5-Dihydroxybenzyl Derivatives from Symphyocladia latiuscula through PTP1B Downregulation and α-Glucosidase Inhibition

Marine Drugs, 2019
The marine alga, Symphyocladia latiuscula (Harvey) Yamada, is a good source of bromophenols with numerous biological activities. This study aims to characterize the anti-diabetic potential of 2,3,6-tribromo-4,5-dihydroxybenzyl derivatives isolated from S.
Pradeep Paudel, Su Hui Seong, Hye Jin Park, Hyun Ah Jung, Jae Sue Choi   +4 more
doaj   +1 more source