Results 1 to 10 of about 10,058 (190)

Designing selective inhibitors to target NagZ a family 3 glycoside hydrolase [PDF]

open access: yesActa Crystallographica Section A Foundations of Crystallography, 2008
M.D. Balcewich   +4 more
openaire   +1 more source

Synthesis of conformationally constrained inhibitors for glycoside hydrolases

open access: yes, 2019
Glycoside hydrolase (GH) enzymes are clinically relevant biological targets for drug development. Disfunction of the two lysosomal GHs β-glucocerebrosidase and α-galactosidase can lead to Gaucher and Fabry’s disease, respectively. With knowledge of their mechanisms of action it is possible to create compounds that would effectively modulate their ...
openaire   +1 more source

BIOCHEMICAL FUNCTIONAL CHARACTERIZATION AND MOLECULAR BIOLOGY OF PLANT INHIBITOR PROTEINS ACTING AGAINST GLYCOSIDE HYDROLASE

open access: yes, 2017
Plant cell walls are composed mostly of polysaccharides and it consist of three layers (the primary cell wall, the secondary cell wall and the middle lamella) that are made up of different percentage of cellulose, pectins and hemicelluloses. These latter are composed of a linear backbone made up of (1,4)-?-D-glycans with an equatorial configuration ...
openaire   +1 more source

GLYCOSIDE HYDROLASES FROM FRESHWATER FISH GILL MICROBIOTA AS BIOFILM INHIBITORS FOR ENHANCED FOOD SAFETY [PDF]

open access: yes
The formation of biofilms by foodborne pathogens is a constant challenge in the food industry, leading to an increased risk of contamination and compromising food safety. Many of the chemicals commonly used for sanitation in the food industry are unable to remove biofilms, are harmful to surfaces and can be toxic. The effectiveness of disinfectants can
Atanasković, Marija   +6 more
openaire  

Structural analysis of a newly identified class of plant protective microbial glycoside hydrolase inhibitors [PDF]

open access: yesActa Crystallographica Section A Foundations of Crystallography, 2004
S. Sansen   +6 more
openaire   +1 more source

Home - About - Disclaimer - Privacy