Iminosugar inhibitors of carbohydrate-active enzymes that underpin cereal grain germination and endosperm metabolism [PDF]
Starch is a major energy store in plants. It provides most of the calories in the human diet and, as a bulk commodity, it is used across broad industry sectors.
Alison M. Smith +57 more
core +2 more sources
Genome-wide analysis of excretory/secretory proteins in Echinococcus multilocularis: insights into functional characteristics of the tapeworm secretome [PDF]
Venn diagrams of expression levels of ES protein coding genes in different developments. The venn diagrams are displayed for: the genes that have expressions (A), the genes with very high expression levels (B), the genes with high expression levels (C ...
Shuai Wang, Wei Wei, Xuepeng Cai
core +8 more sources
Small Molecule Inhibitors of a Glycoside Hydrolase Attenuate Inducible AmpC-mediated β-Lactam Resistance [PDF]
The increasing spread of plasmid-borne ampC-ampR operons is of considerable medical importance, since the AmpC beta-lactamases they encode confer high level resistance to many third generation cephalosporins. Induction of AmpC beta-lactamase from endogenous or plasmid-borne ampC-ampR operons is mediated by a catabolic inducer molecule, 1,6-anhydro-N ...
Keith A, Stubbs +3 more
openaire +2 more sources
For 12 isolates of Ilyonectria mors-panacis and 4 isolates of Ilyonectria robusta, the number of genes in the secretome showed a negative correlation with growth rates in culture, especially for small secreted non-cysteine-rich and cysteine-rich proteins,
Paul H. Goodwin +2 more
doaj +1 more source
Targeted metatranscriptomics of compost derived consortia reveals a GH11 exerting an unusual exo-1,4-β-xylanase activity [PDF]
Background: Using globally abundant crop residues as a carbon source for energy generation and renewable chemicals production stands out as a promising solution to reduce current dependency on fossil fuels.
A Bacic +98 more
core +1 more source
Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut [PDF]
The human gastrointestinal tract harbours myriad bacterial species, collectively termed the microbiota, that strongly influence human health. Symbiotic members of our microbiota play a pivotal role in the digestion of complex carbohydrates that are ...
Brumer, Harry +10 more
core +3 more sources
Genome-wide transcriptional analysis of super-embryogenic
Background The Medicago truncatula (M. truncatula) line 2HA has a 500-fold greater capacity to regenerate plants in culture by somatic embryogenesis than its wild type progenitor Jemalong.
Rolfe Barry G +3 more
doaj +1 more source
Molecular evolution of glycoside hydrolase genes in the Western corn rootworm (Diabrotica virgifera virgifera). [PDF]
Comparative StudyJournal ArticleResearch Support, Non-U.S. Gov'tCellulose is an important nutritional resource for a number of insect herbivores. Digestion of cellulose and other polysaccharides in plant-based diets requires several types of enzymes ...
Benson, AK +7 more
core +1 more source
Azasugars are known as potent inhibitors of glycoside hydrolases. In this study, we examined the inhibition of Cellvibrio gilvus cellobiose phosphorylase (CBP) by four azasugars (isofagomine, 1-deoxynojirimycin, castanospermine and calystegine B2) and a non-azasugar (glucono-1,5-lactone).
Shinya Fushinobu +5 more
openaire +2 more sources
This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang +6 more
wiley +1 more source

