Results 61 to 70 of about 5,356 (159)
Harnessing Trace Elements: Novel Radiosensitization Strategies for Enhanced Cancer Radiotherapy
Rare Metals, Volume 45, Issue 6, June 2026.ABSTRACT Radiotherapy (RT) is one of the core methods of comprehensive cancer treatment. Globally, more than 40% of cancer patients rely on radiotherapy to achieve tumor control, cure or palliative relief. However, radiation resistance, immunosuppression and normal tissue injury limit its clinical application.
Yuhuan Zhang +6 more
wiley +1 more source
Evolutionary Applications, Volume 19, Issue 6, June 2026.ABSTRACT High‐altitude environments expose mammals and their gut symbionts to multifaceted stressors—hypoxia, cold, and intense UV radiation. Whether gut microbial communities undergo compositional restructuring in response to these stressors, and whether such restructuring carries translational value for captive conservation, remain unresolved ...
Feiyun Huang +12 more
wiley +1 more source
Journal of Integrative Plant Biology, Volume 68, Issue 6, Page 1794-1814, June 2026.In soybean, the trihelix transcription factor GmGT‐2F positively regulates the expression of the α‐galactosidase gene GmAGAL, thereby modulating seed oil content. The cyclophilin GmCYP2 interacts with GmGT‐2F and suppresses GmAGAL activation. Haplotype diversity analysis of GmGT‐2F, GmCYP2, and GmAGAL identified favorable haplotype combinations ...
Shuangzhe Li +6 more
wiley +1 more source
ESCRT: A Cellular Nexus of Plant Immunity and Pathogen Counter‐Strategies
Molecular Plant Pathology, Volume 27, Issue 6, June 2026.The endosomal sorting complex required for transport (ESCRT) plays multifaceted roles in plants' responses to pathogens, including regulation of the localization and fate of immune receptors and other related cellular processes. ABSTRACT The endosomal sorting complex required for transport (ESCRT) machinery consists of multiprotein complexes conserved ...
Willam Kyle Sexton, Shunyuan Xiao
wiley +1 more source
Plant Biotechnology Journal, Volume 24, Issue 6, Page 3573-3593, June 2026.ABSTRACT Sheath blight disease of rice caused by the fungal pathogen R. solani AG1‐IA remains a big threat to rice production worldwide. A limited genetic variation in rice for tolerance to this pathogen and little success in understanding how it defeats host defence are major reasons behind it.
Vinod Kumar +5 more
wiley +1 more source
Synthesis of conformationally constrained inhibitors for glycoside hydrolases
, 2019 Glycoside hydrolase (GH) enzymes are clinically relevant biological targets for drug development. Disfunction of the two lysosomal GHs β-glucocerebrosidase and α-galactosidase can lead to Gaucher and Fabry’s disease, respectively. With knowledge of their mechanisms of action it is possible to create compounds that would effectively modulate their ...
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Designing selective inhibitors to target NagZ a family 3 glycoside hydrolase [PDF]
Acta Crystallographica Section A Foundations of Crystallography, 2008 M.D. Balcewich +4 more
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, 2017 Plant cell walls are composed mostly of polysaccharides and it consist of three layers (the primary cell wall, the secondary cell wall and the middle lamella) that are made up of different percentage of cellulose, pectins and hemicelluloses. These latter are composed of a linear backbone made up of (1,4)-?-D-glycans with an equatorial configuration ...
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Structural analysis of a newly identified class of plant protective microbial glycoside hydrolase inhibitors [PDF]
Acta Crystallographica Section A Foundations of Crystallography, 2004 S. Sansen +6 more
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GLYCOSIDE HYDROLASES FROM FRESHWATER FISH GILL MICROBIOTA AS BIOFILM INHIBITORS FOR ENHANCED FOOD SAFETY [PDF]
The formation of biofilms by foodborne pathogens is a constant challenge in the food industry, leading to an increased risk of contamination and compromising food safety. Many of the chemicals commonly used for sanitation in the food industry are unable to remove biofilms, are harmful to surfaces and can be toxic. The effectiveness of disinfectants can
Atanasković, Marija +6 more
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