Results 71 to 80 of about 46,608 (304)

A Practical and Flexible De Novo Synthesis of Deoxygenated Carbasugars and Their Cyclitol Epoxides

European Journal of Organic Chemistry, EarlyView.
A de novo synthesis route comprising enantioselective Brown crotylation and ring‐closing metathesis as the key steps enables the synthesis of a‐ and b‐carba‐paratose, a‐ and b‐carba‐colitose as well as four configurational deoxycyclophellitol isosteres.
Yevhenii Radchenko, Nick D. F. Puijmbroeck, Sanne M. Verduin, Jeroen D. C. Codée, Herman S. Overkleeft   +4 more
wiley   +1 more source

Biochemical properties of digestive carbohydrases from the sugar beet weevil, Lixus incanescens (Coleoptera: Curculionidae) [PDF]

Arthropods, 2013
The sugar beet weevil, Lixus incanescens B., is one of the most important pests of sugar beet plant in Iran. The petioles and leaves of sugar beet are attacked by larvae and adults of the sugar beet weevil.
Seyed Mohammad Ahsaei, Vahid Hosseininaveh, Mahdieh Bigham   +2 more
doaj  

Flavonoids with α-glucosidase inhibitory activities and their contents in the leaves of Morus atropurpurea [PDF]

, 2013
BACKGROUND: This study aims to isolate the α-glucosidase inhibitory compounds from mulberry leaves (Morus atropurpurea Roxb., Moraceae) and to develop an analytical method for quantification of the compounds.
Hin-Chu Hong, Qing-Wen Zhang, Song-Lin Li, Wen-Cai Ye, Xiao-Qi Zhang   +4 more
core   +1 more source

Sodium‐glucose cotransporter 2 inhibitors and the risk of late onset epilepsy: A real‐world cohort study

Epilepsia, EarlyView.
Abstract Objective Late onset epilepsy (LOE) is associated with substantial morbidity. Sodium‐glucose cotransporter 2 inhibitors (SGLT2i) may exert neuroprotective effects. This study evaluated the association between SGLT2i and risk of LOE among older adults with type 2 diabetes mellitus.
Bing‐Hua Lin, Hui‐Min Huang, Hui‐An Lin, Sheng‐Feng Lin   +3 more
wiley   +1 more source

Crystal Structure of Thermotoga maritima α-Glucosidase AglA Defines a New Clan of NAD+-dependent Glycosidases [PDF]

, 2003
Glycoside hydrolase family 4 represents an unusual group of glucosidases with a requirement for NAD(+), divalent metal cations, and reducing conditions. The family is also unique in its inclusion of both alpha- and beta-specific enzymes.
Hoffmann, Volker, Liebl, Wolfgang, Lodge, Jacinta A., Maier, Timm, Sträter, Norbert   +4 more
core   +2 more sources

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

.ALPHA.-Glucosidase Inhibitors from Millettia conraui

Chemical and Pharmaceutical Bulletin, 2007
A new geranylated isoflavone, 7-O-geranyl-6-methoxypseudobaptigenin (1) was isolated from the stem barks of Millettia conraui, along with known compounds 5-methoxydurmillone (2), conrauinone A (3), beta-amyrine (4), sitosterol (5), 3-O-beta-D-glucopyranosyl sitosterol (6) and n-docosanol (7).
Alembert, Tiabou Tchinda, Shamsun, Nahar Khan, Victorine, Fuendjiep, François, Ngandeu, Annie, Ngono Ngane, Muhammad Iqbal, Choudhary   +5 more
openaire   +3 more sources

Recent Progress on Enzyme Immobilization: Materials, Strategies, and Applications

Food Bioengineering, EarlyView.
Enzyme immobilization technology has undergone substantial evolution driven by advances in materials science. This review systematically examines the recent advances in enzyme immobilization since 2024, with a focused analysis of five major categories of enzyme carriers including covalent organic framework, metal‐organic frameworks, polymers, carbon ...
Shuran Wang, Ruoke Li, Yixuan Xie, Hanya Zhang, Xiaoyu Huang, Siwei Chen, Weixin Xu, Yueling Liu   +7 more
wiley   +1 more source

Acantholippia salsoloides : Phytochemical Composition and Biological Potential of a Thujonic Population [PDF]

, 2019
Acantholippia salsoloides (Verbenaceae) is an aromatic plant widespread in the Andean region. The infusion (leaves and flowers) is widely used as a digestive stimulant as well as for the treatment of various diseases in traditional medicine.
Celaya, Liliana Soledad, Silva, Luís R., Viturro, Carmen Ines   +2 more
core   +1 more source

Antioxidant Activity and Inhibition of Carbohydrate Hydrolyzing Enzymes by Underutilized Parts From Some Plant‐Based Foods and Their Effect on Postprandial Hyperglycemia

Food Chemistry International, EarlyView.
The underutilized parts viz: pawpaw seed, banana, plantain, and potato peels showed promising antioxidant and inhibition of α‐amylase and α‐glucosidase activities (IC50 values ≤ 100 μg/mL). Similarly, pawpaw seed, banana, plantain, and potato peels reduced postprandial hyperglycemia in sucrose‐ and maltose‐induced hyperglycemia in rats.
Aminu Mohammed, Buhari Shehu Saidu, Nuhu Aliyu, Michael Peter Simon   +3 more
wiley   +1 more source