Results 61 to 70 of about 46,608 (304)

Antioxidant activities and inhibitory effects of free and bound polyphenols from date (Phoenix dactylifera L.) seeds on starch digestive enzymes

International Journal of Food Studies, 2016
Date (Phoenix dactylifera L.) seeds have gained interest as a valuable by-product of the date fruit industry and have been identified as a rich source of functional and bioactive ingredients. In this study, date seeds from five varieties (Medjool, Deglet
Sameera Sirisena, Ken Ng, Said Ajlouni   +2 more
doaj   +1 more source

High Sustained Antibody Titers in Patients with Classic Infantile Pompe Disease Following Immunomodulation at Start of Enzyme Replacement Therapy [PDF]

, 2018
Objective: To evaluate whether immunomodulation at start of enzyme replacement therapy induces immune tolerance to recombinant human acid alpha-glucosidase (rhGAA) in patients with classic infantile Pompe disease.
Bronsema, K.J. (Kees J.), Hoogeveen-Westerveld, M. (Marianne), Hout, J.M.P. (Johanna) van den, Kroos-de Haan, M.A. (Marian A.), Pijnappel, W.W.M.P. (Pim), Ploeg, A.T. (Ans) van der, Poelman, E. (Esther), Van De Merbel, N.C. (Nico C.)   +7 more
core   +4 more sources

Trends in the utilization, expenditure and costs of noninsulin glucose‐lowering drugs in the Medicaid population: Steady increases in glucagon‐like peptide‐1 receptor agonist and sodium–glucose transporter‐2 inhibitor use, prices and expenditure

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to analyse changes in the utilization, expenditure and average cost of noninsulin glucose‐lowering drugs (GLDs) between 2008 and 2023. Methods This was a retrospective observational study of 2008–2023 data from the National Medicaid State Drug Utilization database.
Rawan O. Almadfaa
wiley   +1 more source

Synthesis and Glycosidase Inhibition Studies of Novel Exoglycals Targeting GH3 Family Enzymes: Insights from Comparative Analysis with Macrolide Antibiotics

Chemistry – A European Journal, EarlyView.
A series of structurally diverse exoglycals was synthesized using a modified Julia‐olefination approach from sugar‐derived precursors. These glycosidase transition‐state mimics were further diversified via CuAAC chemistry to yield triazole‐conjugated analogues.
Elisa Ospanow, Oscar L. Alferez, David L. Jakeman   +2 more
wiley   +1 more source

Smallanthus sonchifolius (Yacon) leaves: an emerging source of compounds for diabetes management [PDF]

, 2015
Diabetes mellitus is a chronic metabolic disease that develops mainly due to insulin deficiency or resistance to insulin action. All forms of diabetes are characterized by chronic hyperglycemia, which has an important role in the pathogenesis of diabetic
Genta, Susana Beatriz de Fátima, Honore, Stella Maris, Sanchez, Sara Serafina del V.   +2 more
core  

Salvia libanotica improves glycemia and serum lipid profile in rats fed a high fat diet [PDF]

, 2015
Background Salvia libanotica (S. Libanotica) is a commonly used herb in folk medicine in Lebanon and the Middle East. The present study aimed to assess the scientific basis for the therapeutic use of S. libanotica in glycemia and to evaluate its effects
Bassil, Maya, Daher, Costantine F., Mroueh, Mohammad, Zeeni, Nadine   +3 more
core   +1 more source

N‐Glycosyl Triazoline Glycomimetics via Huisgen Cycloaddition With an Electron‐Deficient Alkene and BF3‐Catalysed Triazoline Fragmentation to Aziridines

European Journal of Organic Chemistry, EarlyView.
Glycomimetics with triazoline and aziridine groups were synthesised via diastereoselective Huisgen cycloaddition from glycosyl azides. Density functional theory was applied to define the mechanism for BF3 promoted aziridine formation. Triazoline and aziridine derivatives were synthesised by diastereo‐ and regioselective Huisgen cycloaddition of 2,3,4,6‐
Aaron McCormack, Ashis Dhara, Lamis Alaa Eldin Refat, Mikael Bols, Paul V. Murphy   +4 more
wiley   +1 more source

Alpha-Glucosidase inhibitory activity in hexane extracts of some plants from kurdistan province

Journal of Medicinal Plants, 2016
Background: Diabetes mellitus is a most serious and chronic disease that is characterized by high blood glucose levels, especially after feeding, namely postprandial hyperglycemia.
MS Poursharifi, MA Zarei
doaj  

Exploring anti-diabetic potential of compounds from roots of Dendrobium polyanthum Wall. ex Lindl. through inhibition of carbohydrate-digesting enzymes and glycation inhibitory activity

Heliyon
Eight compounds, including one anthraquinone, two bibenzyls, one phenanthrene, three dihydrophenanthrenes, and one flavonoid, were isolated from the roots of Dendrobium polyanthum Wall. ex Lindl.
Thaniwan Cheun-Arom, Tharita Kitisripanya, Poomraphie Nuntawong, Boonchoo Sritularak, Taksina Chuanasa   +4 more
doaj   +1 more source

Aktivitas Inhibisi Alfa Glukosidase Pada Beberapa Jenis Kulit Kayu Raru [PDF]

, 2011
Raru merupakan sebutan untuk jenis kulit kayu yang ditambahkan pada nira aren yang bertujuan untuk meningkatkan cita rasa, kadar alkohol dan mengawetkan minuman tradisional tuak.
Pasaribu, G. (Gunawan)
core   +2 more sources