Results 91 to 100 of about 59,298 (179)

Structure and dynamics of the aggregation mechanism of the Parkinson´s disease-associated protein alpha-synuclein [PDF]

, 2006
Carlos W. Bertoncini
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Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain [PDF]

, 2007
Andisheh Eslamboli, Marina Romero‐Ramos, Corinna Bürger, Tomas Björklund, Nicholas Muzyczka, Ronald J. Mandel, Harry F. Baker, R.M. Ridley, Deniz Kirik   +8 more
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25. The Role of Alpha-Synuclein (α-syn) Phosphorylation at Ser-129 on the Development of Parkinson-Like Neurodegeneration [PDF]

, 2007

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Faculty Opinions recommendation of Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models.

, 2006
Adam D. Linstedt
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Inhibitory effect of Scutellaria pinnatifida Extracts on the Alpha synuclein Cytotoxicity

Journal of Medicinal Plants, 2019
Many of neurodegenerative diseases (NDs) are associated with formation of the protein aggregates called amyloidal fibrils. Fibrillization of alpha-synuclein seems to be a key stage in the creation and progression of NDs and finding the compounds that ...
Mahdieh Sashourpour, Dina Morshedi, Saber Zahri, Farhang Ali akbari, Marzieh Fottovat, Tayebeh Rajabian   +5 more
doaj  

Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity [PDF]

, 2008
Liyan Qiao, Shusei Hamamichi, Kim A. Caldwell, Guy A. Caldwell, Talene A. Yacoubian, Scott M. Wilson, Zuolei Xie, Lisa D Speake, Rachael Parks, Donna Crabtree, Qiuli Liang, Stephen Crimmins, Lonnie Schneider, Yasuo Uchiyama, Takeshi Iwatsubo, Yi Zhou, Lisheng Peng, Youming Lu, David G. Standaert, Ken C. Walls, John J. Shacka, Kevin A. Roth, Jianhua Zhang   +22 more
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Using a stable protein scaffold to display peptides that bind to alpha-synuclein fibrils. [PDF]

Protein Sci
Bismut S, Schneider MM, Miyasaki M, Feng Y, Wilde EJ, Gunawardena MD, Knowles TPJ, Kaminski Schierle GS, Itzhaki LS, Kumita JR.   +9 more
europepmc   +2 more sources

Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminals: Autonomic pathway implicated in Parkinson's disease? [PDF]

, 2008
Robert Phillips, Gary C. Walter, S.L. Wilder, Elizabeth A. Baronowsky, Terry L. Powley   +4 more
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Dopamine auto‐oxidation aggravates non‐apoptotic cell death induced by over‐expression of human A53T mutant alpha‐synuclein in dopaminergic PC12 cells [PDF]

, 2008
Zhidong Zhou, Sze Yen Kerk, Gao Gao Xiong, Tit Meng Lim   +3 more
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Ultrastructural localization of Porphyromonas gingivalis gingipains in the substantia nigra of Parkinson’s disease brains

npj Parkinson's Disease
Gingipains are protease virulence factors produced by Porphyromonas gingivalis, a Gram-negative bacterium best known for its role in chronic periodontitis. Gingipains were recently identified in the middle temporal gyrus of postmortem Alzheimer’s disease
Florian Ermini, Victoria F. Low, Jennifer J. Song, Adelie Y. S. Tan, Richard L. M. Faull, Michael Dragunow, Maurice A. Curtis, Stephen S. Dominy   +7 more
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