Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminals: Autonomic pathway implicated in Parkinson's disease? [PDF]
Robert Phillips +4 more
openalex +1 more source
Neuronal THY1 Signaling Maintains Astrocytes in a Quiescent State
THY1‐bearing neurons keep astrocytes in a quiescent state via the interaction with ITGB1. Depletion of THY1 supports the development of a partially activated astrocyte phenotype. Neuronal THY1 is involved in the maintenance and restoration of tissue homeostasis in the brain. ABSTRACT THY1 is a cell surface protein of mature neurons.
Juliane Loui +6 more
wiley +1 more source
Dopamine auto‐oxidation aggravates non‐apoptotic cell death induced by over‐expression of human A53T mutant alpha‐synuclein in dopaminergic PC12 cells [PDF]
Zhidong Zhou +3 more
openalex +1 more source
Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley +1 more source
Inhibitory effect of Scutellaria pinnatifida Extracts on the Alpha synuclein Cytotoxicity
Many of neurodegenerative diseases (NDs) are associated with formation of the protein aggregates called amyloidal fibrils. Fibrillization of alpha-synuclein seems to be a key stage in the creation and progression of NDs and finding the compounds that ...
Mahdieh Sashourpour +5 more
doaj
Progress of non‐motor symptoms in early‐onset Parkinson's disease
This study reviews the research progress related to non‐motor symptoms (NMS) in patients with early onset Parkinson's disease (EOPD), including neuropsychiatric symptoms, autonomic dysfunction, sleep disorders, and sensory disorders and also summarizes the characteristics of NMS in the genetic form of Parkinson's disease (PD).
Fanshi Zhang +5 more
wiley +1 more source
Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity [PDF]
Liyan Qiao +22 more
openalex +1 more source
Direct Detection of Viruses Using Antibody‐Modified Gold Nanorods
Gold nanorods functionalized with pathogen‐specific antibodies can be used for the confirmatory detection of viruses via dynamic light scattering–based analysis of particle sizes. ABSTRACT Seasonal and sporadic viral infections put enormous burdens on global health and society. Although polymerase chain reaction (PCR) and other molecular approaches can
Axell Rodriguez +3 more
wiley +1 more source
Nitrated Alpha-Synuclein and Microglial Neuroregulatory Activities [PDF]
Ashley Reynolds +7 more
openalex +1 more source

