Results 91 to 100 of about 32,142 (226)

Knowledge, Attitude, and Perception of Nursing Students in Selected Private Universities on Integration of Genomic Information Into Clinical Assessment and Patient Education: A Descriptive Cross‐Sectional Survey

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims The rapid growth of genomics in healthcare has led to significant advances, and the integration of genetic information into clinical and patient education among nursing students during their training years is crucial to equip them for the genomic era.
Iyanuoluwa Oreofe Ojo, Toluwanimi Anuoluwapo Asumo, Ajibola Omobola Ojo, Prisca Olabisi Adejumo   +3 more
wiley   +1 more source

The Role of Haemoglobin Variants and Red Blood Cell Polymorphisms in Asymptomatic Malaria: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Human phenotypes, particularly blood group polymorphisms (ABO) and haemoglobin variants (HbAA and HbAS), have been widely studied in relation to clinical malaria. However, their role in asymptomatic malaria remains underexplored. This study therefore, investigated the association of these phenotypic variants with the burden
Enoch Aninagyei, Comfort Addo Boatey, John Gameli Deku, Adjoa Agyemang Boakye, Ebenezer Nyarkotey, Gifty Larbi, Desmond Omane Acheampong   +6 more
wiley   +1 more source

An Integrated Genotyping Strategy for α/β‐Thalassemia: Based on the Analysis of the Coding Sequences and Expression Levels of HBA2, HBA1, and HBB in Peripheral Blood mRNA

Journal of Clinical Laboratory Analysis, Volume 40, Issue 7, April 2026.
We have developed an integrated mRNA‐based strategy for thalassemia genotyping. Its characteristics included using only three Sanger sequencing reactions to analyze the full‐length coding sequence of HBA2, HBA1 and HBB, and employing a new multiple quantitative fluorescence PCR to simply assess and present the impact of common mutations on the ...
Hongjian Chen, Qi Yao, Mianai Fu
wiley   +1 more source

Effect of Tonsillar Retractor on Intracranial and Intraocular Pressure in Children Undergoing Adenotonsillectomy Surgeries

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 2, April 2026.
The effect of tonsillar retractor placement on IOP and ONSD values. ABSTRACT Objectives The tonsillar retractor used during adenotonsillectomy, one of the most common pediatric surgeries, may increase sympathetic activity. This study aimed to evaluate the effect of tonsillar retractor insertion on intracranial pressure (ICP) and intraocular pressure ...
Ayse Bozkurt Oflaz, Meltem Isık, Merih Onal, Mete Kaan Bozkurt, Ozkan Onal, Banu Bozkurt   +5 more
wiley   +1 more source

Chromatin Regulation of DNA Damage Repair and Genome Integrity in the Central Nervous System [PDF]

, 2017
With the continued extension of lifespan, aging and age-related diseases have become a major medical challenge to our society. Aging is accompanied by changes in multiple systems. Among these, the aging process in the central nervous system is critically
Pan, Ling, Penney, Jay, Tsai, Li-Huei
core   +1 more source

Isocitrate Dehydrogenase‐Mutant Astrocytomas: Risk Stratification and Therapeutic Advance

MedComm, Volume 7, Issue 4, April 2026.
This graphical abstract synthesizes the core logic of our revised review by linking integrated diagnosis, risk stratification, and trajectory‐based management in IDH‐mutant astrocytomas across CNS WHO Grades 2–4. It highlights lineage‐defining molecular classification (IDH mutation with core co‐alterations), integrated histomolecular grading, and key ...
Shepeng Wei, Xuxu Xu, Jing Bao, Zhenjiang Pan   +3 more
wiley   +1 more source

An investigation of the protective effect of alpha+-thalassaemia against severe Plasmodium falciparum amongst children in Kumasi, Ghana [PDF]

Background: The alpha+-thalassaemias are the most common monogenic disorders of humans, characterised by microcytic and hypochromic anaemia. Their high frequency reflects selective advantage against death from Plasmodium falciparum malaria.
Opoku-Okrah, C., Opoku-Okrah, C.
core  

Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care

International Journal of Laboratory Hematology, Volume 48, Issue 2, Page 295-304, April 2026.
ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley   +1 more source

AAPT Diagnostic Criteria for Chronic Sickle Cell Disease Pain [PDF]

, 2017
Pain in sickle cell disease (SCD) is associated with increased morbidity, mortality, and high health care costs. Although episodic acute pain is the hallmark of this disorder, there is an increasing awareness that chronic pain is part of the pain ...
Aguilar, Ameringer, Ballas, Ballas, Ballas, Barakat, Bediako, Brandow, Brandow, Bruehl, Campbell, Campbell, Carlton Dampier, Carroll, Carroll, Carroll, Crawford, Dampier, Dampier, Dampier, Dampier, Dampier, Dampier, Darbari, Darbari, Darbari, DeBaun, Deepika S. Darbari, Dworkin, Dyson, Edwards, Fillingim, Fillingim, Franck, Gil, Gil, Hassell, Hoff, Houston-Yu, Igbineweka, Jonassaint, Kathryn Hassell, Kato, Kauf, Koshy, Levenson, Lewandowski, Long, Mahadeo, Maixner, Mathur, McClish, Milner, Minniti, Minniti, Myrvik, Niebanck, Palermo, Palermo, Palermo, Paul, Platt, Powars, Raphael, Savitt, Schwartz, Serarslan, Serjeant, Shapiro, Sil, Smith, Smith, Sogutlu, Steinberg, Taylor, Tonya M. Palermo, Tsao, Turk, Valrie, Vance, Vardeh, Walco, Walco, Wallen, Wally Smith, Wilkie, William Zempsky, Wison Schaeffer, Yawn, Zempsky   +89 more
core   +3 more sources

ACMG/AMP‐Based Variant Classification of a Novel HBA2 Variant (HBA2: C.297del, Hb Taiping) in Compound Heterozygosity With Hb Adana (HBA2:C.179G>A) Causing Non‐Deletional Hb H Disease

International Journal of Laboratory Hematology, Volume 48, Issue 2, Page 458-465, April 2026.
ABSTRACT Background Accurate classification of novel globin gene variants is critical for the diagnosis and management of thalassaemia. The adaptation of ACMG/AMP guidelines for globin genes represents an important step toward standardising variant interpretation and enhancing clinical utility in the field.
Norafiza Mohd Yasin, Suguna Somasundram, Syahzuwan Hassan, Nur Aisyah Aziz, Faidatul Syazlin Abdul Hamid, Ezzanie Suffya Zulkefli, Nor Nazuha Mohamad, Chin Ming Lee, Mohd Nazif Darawi, Thessalia Papasavva, Coralea Stephanou, Petros Kountouris, Sandra J. G. Arkesteijn, Tamara Koopman, Cornelis L. Harteveld   +14 more
wiley   +1 more source