Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis [PDF]
, 2008 Women develop chronic inflammatory autoimmune diseases like lupus more often than men. The mechanisms causing the increased susceptibility are incompletely understood, although estrogen is believed to contribute.
Anura Hewagama +4 more
core +1 more source
Transforming Growth Factor Beta 2 and Heme Oxygenase 1 Genes Are Risk Factors for the Cerebral Malaria Syndrome in Angolan Children [PDF]
, 2013 BACKGROUND: Cerebral malaria (CM) represents a severe outcome of the Plasmodium falciparum infection. Recent genetic studies have correlated human genes with severe malaria susceptibility, but there is little data on genetic variants that increase the
Benchimol, Carla +13 more
core
Effect of booklet and combined method on parents' awareness of children with β-thalassemia major disorder [PDF]
, 2008 OBJECTIVE: To assess the effects of booklet and combining methods (lecture, video, etc.) on parents' awareness of children with beta-thalassemia major disorder.
Hasanpour-Dehkordi, A. +1 more
core
Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium. [PDF]
, 2018 Adult diffuse gliomas are a diverse group of brain neoplasms that inflict a high emotional toll on patients and their families. The Cancer Genome Atlas and similar projects have provided a comprehensive understanding of the somatic alterations and ...
GLASS Consortium
core
Prevalence of common point mutations of alpha globin gene in Babol, Iran (2005-09)
مجله دانشگاه علوم پزشکی گرگان, 2012 Background and Objective: Alpha thalassemia is one of the most common hemoglobin disorders. Some combination of alpha globin gene mutations may cause HbH disease with severe anemia or intermediate thalassemia.
Akhavan-Niaki H (PhD) +4 more
doaj
Sickle Cell Disease and H3Africa: Enhancing Genomic Research on Cardiovascular Diseases in African Patients. [PDF]
Sickle cell disease (SCD) has a high prevalence in sub-Saharan Africa. There are several cardiovascular phenotypes in SCD that contribute to its morbidity and mortality.
Makani, Julie +6 more
core +1 more source
Frequency of alpha-thalassemia in Greece.
American journal of hematology, 1986 Using hematological and gene mapping techniques, a cord blood survey was carried out to estimate the frequency of alpha-thalassemia in the Greek population. Out of 227 newborns studied, 16 (7.05%) were found by gene mapping to be alpha-thalassemia 2 heterozygotes (-alpha/alpha alpha), and of these only two had increased levels of hemoglobin Bart's in ...
KANAVAKIS, E +4 more
openaire +2 more sources
Comparison of the HbH inclusion test and a PCR test in routine screening for α thalassaemia in Hong Kong [PDF]
, 1996 Aim - To compare the haemoglobin (Hb) H inclusion test with a polymerase chain reaction CPCR) test in routine screening for or thalassaemia. Methods - Ninety nine peripheral blood samples from Chinese patients with mean corpuscular volume below 80fl were
Chan, AYY, Chan, LC, So, CKC
core
Preimplantation Genetic Diagnosis for Alpha Thalassemia: Experience in Siriraj Hospital
Siriraj Medical Journal, 2008 Objective: Detection of fetal thalassemia using preimplantation genetic diagnosis (PGD) can make a diagnosis before pregnancy so termination of pregnancy in that patient is eliminated.
Japarath Prechapanich +5 more
doaj
Rapid turnover of T cells in acute infectious mononucleosis.
, 2003 During acute infectious mononucleosis (AIM), large clones of Epstein-Barr virus-specific T lymphocytes are produced. To investigate the dynamics of clonal expansion, we measured cell proliferation during AIM using deuterated glucose to label DNA of ...
Asquith, Becca +9 more
core +1 more source