Analysis of Migration and Adaptive Evolution in Tibetan Sheep Populations
AnimalsThe genetic basis for Tibetan sheep adaptation to different high-altitude environments remains unknown. This study conducted whole-genome resequencing on 80 Tibetan sheep individuals from four major distribution areas on the Qinghai–Tibet Plateau.
Wentao Zhang +6 more
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Gz, a guanine nucleotide-binding protein with unique biochemical properties [PDF]
, 1990 Cloning of a complementary DNA (cDNA) for Gz alpha, a newly appreciated member of the family of guanine nucleotide-binding regulatory proteins (G proteins), has allowed preparation of specific antisera to identify the protein in tissues and to assay it ...
Casey, Patrick J. +3 more
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Contribution of the cyclic nucleotide gated channel subunit, CNG-3, to olfactory plasticity in Caenorhabditis elegans. [PDF]
, 2017 In Caenorhabditis elegans, the AWC neurons are thought to deploy a cGMP signaling cascade in the detection of and response to AWC sensed odors. Prolonged exposure to an AWC sensed odor in the absence of food leads to reversible decreases in the animal's ...
BT Juang +39 more
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Distinct forebrain and cerebellar isozymes of type II Ca^(2+)/calmodulin-dependent protein kinase associate differently with the postsynaptic density fraction [PDF]
, 1985 Forebrain and cerebellar Type II Ca2+/calmodulin-dependent protein kinases have different subunit compositions. The forebrain holoenzyme, characterized in our laboratory, is a 650-kDa holoenzyme composed of 50-kDa alpha-subunits and 60-kDa beta-subunits ...
Kennedy, Mary B., Miller, Stephen G.
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Mechanisms underlying the functional cooperation between PPARα and GRα to attenuate inflammatory responses [PDF]
, 2019 Glucocorticoids (GCs) act via the glucocorticoid receptor (NR3C1, GR alpha) to combat overshooting responses to infectious stimuli, including lipopolysaccharide (LPS).
Beck, Ilse +9 more
core +1 more source
Targeting glutamate synthase for tuberculosis drug development [PDF]
, 2011 1. The Mycobacterium tuberculosis glutamate synthase consisting of alpha and beta subunits can be purified in a heterologous Escherichia coli expression system. 2.
Cheung, YW, Tanner, JA
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Czech Journal of Animal Science, 2019 Haemoglobin (HB), the most widely distributed respiratory pigment in the animal kingdom, is among the best characterized oxygen-binding proteins, both at functional and molecular level.
Rosario Rullo +3 more
doaj +1 more source
Functional expression of the yeast alpha-factor receptor in Xenopus oocytes [PDF]
, 1989 The STE2 gene of the yeast Saccharomyces cerevisiae encodes a 431- residue polypeptide that has been shown by chemical cross-linking and genetic studies to be a component of the receptor for the peptide mating pheromone, alpha-factor.
Blumer, Kendall J. +4 more
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3D structure of muscle dihydropyridine receptor
European Journal of Translational Myology, 2015 Excitation contraction coupling, the rapid and massive Ca2+ release under control of an action potential that triggers muscle contraction, takes places at specialized regions of the cell called triad junctions.
Montserrat Samsó
doaj +1 more source
The alpha 1/beta 1 and alpha 6/beta 1 integrin heterodimers mediate cell attachment to distinct sites on laminin. [PDF]
, 1990 This study was undertaken to determine the roles of individual alpha/beta 1 integrin heterodimers in promoting cellular interactions with the different attachment-promoting domains of laminin (LN). To do this, antibodies to the integrin beta 1 subunit or
Crowley, E +6 more
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