Results 81 to 90 of about 3,104,746 (304)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Nitrogen recycling by the gut microbiome in sarcopenia
Frontiers in MicrobiologyIntroductionSarcopenia, which is defined as loss of skeletal muscle mass and strength, affects up to 70% of patients with liver cirrhosis. Since hibernating animals maintain muscle mass through microbial nitrogen recycling, urease-producing bacteria may ...
Rosa Haller +14 more
doaj +1 more source
Guanabenz Treatment Accelerates Disease in a Mutant SOD1 Mouse Model of ALS.
PLoS ONE, 2015 Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by loss of motor neurons. The mechanisms leading to motor neuron degeneration in ALS are unclear.
Fernando G Vieira +13 more
doaj +1 more source
Biochemical characterization of the GM2 gangliosidosis B1 variant
Brazilian Journal of Medical and Biological Research, 2004 The deficiency of the A isoenzyme of ß-hexosaminidase (Hex) produced by different mutations of the gene that codes for the alpha subunit (Tay-Sachs disease) has two variants with enzymological differences: the B variant consists of the absence of Hex A ...
J.C. Tutor
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Alpha Kappa Alpha: Sisterhood and Service DVD, 2008
, 2008 This documentary tells of AKA's founding at Howard University and celebrates the sorority's history and commitment to service and accomplishment.Archival master image scanned in reflective mode as 48-bit RGB color TIFF using Epson 11000 XL. Display image
Alpha Kappa Alpha
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Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
PLoS ONE, 2019 The reproductive ground plan hypothesis proposes that gene networks regulating foraging behavior and reproductive female physiology in social insects emerged from ancestral gene and endocrine factor networks.
Chloe Hawkings +3 more
doaj +1 more source
Molecular Brain, 2019 Go is a member of the pertussis toxin-sensitive Gi/o family. Despite its abundance in the central nervous system, the precise role of Go remains largely unknown compared to other G proteins.
Hye Lim Cha +6 more
doaj +1 more source
Notes on the founding and membership of the Alpha Rho and BKΩ chapters of AKA, undated
, 1970 Notes narrating the history of the Alpha Rho and BKΩ chapters of Alpha Kappa Alpha, along with memberships lists from various years.Archival master image scanned in reflective mode as 48-bit RGB color TIFF using Epson 11000 XL. Display image is 8-bit 150
Alpha Kappa Alpha
core