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A fusion model integrating magnetic resonance imaging radiomics and deep learning features for predicting alpha-thalassemia X-linked intellectual disability mutation status in isocitrate dehydrogenase-mutant high-grade astrocytoma: a multicenter study. [PDF]

Quant Imaging Med Surg
Liu Z, Xu X, Zhang W, Zhang L, Wen M, Gao J, Yang J, Kan Y, Yang X, Wen Z, Chen S, Cao X.   +11 more
europepmc   +1 more source

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The Clinical Phenotypes of Alpha Thalassemia

Hematology/Oncology Clinics of North America, 2023
Clinical manifestations of α-thalassemia range from no symptoms to severe transfusion-dependent anemia. Alpha thalassemia trait is deletion of 1 to 2 α-globin genes, whereas α-thalassemia major (ATM; Barts hydrops fetalis) is the deletion all 4 α genes.
Ashutosh Lal, Elliott Vichinsky
exaly   +4 more sources

Alpha-Thalassemia: Diversity of Clinical Phenotypes and Update on the Treatment

Thalassemia Reports, 2022
One of the more common single-gene disorders worldwide is α-thalassemia, carriers of which are found at variable frequencies (>1%) across all tropical and subtropical countries.
Duantida Songdej, Suthat Fucharoen, Songdej Duantida   +2 more
exaly   +2 more sources

Advancing Alpha-Thalassemia Carrier Screening for Better Predictions Using Explainable AI

2023 4th International Conference on Communication, Computing and Industry 6.0 (C216), 2023
Thalassemia is a category of inherited blood disorders, becoming a primary health threat due to its increased prevalence worldwide. Through examination and testing of Thalassemia is widely accessible to the people.
Aditya H. Meti, B. Maheswari, Aditya Vijjapu   +2 more
semanticscholar   +1 more source

An online alpha-thalassemia carrier discrimination model based on random forest and red blood cell parameters for low HbA2 cases.

Clinica chimica acta; international journal of clinical chemistry, 2021
BACKGROUND Since screening of α-thalassemia carriers by low HbA2 has a low positive predictive value (PPV), the PPV was as low as 40.97% in our laboratory, other more effective screening methods need to be devised.
Pinning Feng, Yuzhe Li, Z. Liao, Zhenrong Yao, Wenbin Lin, Shuhua Xie, Beini Hu, Chencui Huang, Wei Liu, Hongxu Xu, Min Liu, Wenjia Gan   +11 more
semanticscholar   +1 more source

Co-Inheritance of alpha-thalassemia and sickle cell disease in a cohort of Angolan pediatric patients

Molecular Biology Reports, 2020
Brigida Santos, Mariana Delgadinho, Ana Paula Arez   +2 more
exaly   +2 more sources