Results 111 to 120 of about 13,277 (199)

Determination of Ferret Enteric Coronavirus Genome in Laboratory Ferrets

open access: yesEmerging Infectious Diseases, 2017
Ferret enteric coronavirus (FRECV) RNA was detected in laboratory ferrets. Analysis of the complete genome sequence of 2 strains, FRCoV4370 and FRCoV063, revealed that FRECV shared 49.9%–68.9% nucleotide sequence identity with known coronaviruses.
Tian-Cheng Li   +8 more
doaj   +1 more source

Genetic diversity and ecology of coronaviruses hosted by cavedwelling bats in Gabon [PDF]

open access: yes, 2020
Little research on coronaviruses has been conducted on wild animals in Africa. Here, we screened a wide range of wild animals collected in six provinces and fve caves of Gabon between 2009 and 2015.
ArGouilh, Meriadeg   +10 more
core   +2 more sources

Five‐Year (2017–2022) Evolutionary Dynamics of Human Coronavirus HKU1 in Southern France With Emergence of Viruses Harboring Spike H512R Substitution

open access: yesJournal of Medical Virology, Volume 97, Issue 2, February 2025.
ABSTRACT HCoV‐HKU1 diversity and evolution were scarcely studied. We performed next‐generation sequencing (NGS) and analysis of HCoV‐HKU1 genomes over 5 years. NGS used Illumina technology on NovaSeq 6000 following whole genome PCR amplification by an in‐house set of primers designed using Gemi and PrimalScheme.
Houmadi Hikmat   +9 more
wiley   +1 more source

Development and characterization of segment-specific enteroids from the pig small intestine in Matrigel and transwell inserts: insights into susceptibility to porcine epidemic diarrhea Virus

open access: yesFrontiers in Immunology
IntroductionThe critical early stages of infection and innate immune responses to porcine epidemic diarrhea virus (PEDV) at the intestinal epithelium remain underexplored due to the limitations of traditional cell culture and animal models.
Lu Yen   +6 more
doaj   +1 more source

A molecular arms race between host innate antiviral response and emerging human coronaviruses [PDF]

open access: yes, 2016
Coronaviruses have been closely related with mankind for thousands of years. Communityacquired human coronaviruses have long been recognized to cause common cold.
Jin, D, Lui, PY, Wong, LYR
core   +1 more source

Dynamic Combinatorial Chemistry Unveils Nsp10 Inhibitors with Antiviral Potential Against SARS‐CoV‐2

open access: yesChemistry – A European Journal, Volume 31, Issue 4, January 17, 2025.
This study investigates antiviral strategies targeting SARS‐CoV‐2 by disrupting the protein‐protein interactions of Nsp10 with Nsp14 and Nsp16, which are essential for viral survival. It employs target‐directed dynamic combinatorial chemistry for the identification and synthesis of inhibitors.
Ravindra P. Jumde   +15 more
wiley   +1 more source

Detection of alpha- and betacoronaviruses in rodents from Yunnan, China

open access: yesVirology Journal, 2017
Background Rodents represent the most diverse mammals on the planet and are important reservoirs of human pathogens. Coronaviruses infect various animals, but to date, relatively few coronaviruses have been identified in rodents worldwide.
Xing-Yi Ge   +6 more
doaj   +1 more source

Genetics and epidemiology of Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) [PDF]

open access: yes, 2015
Background: Middle East respiratory syndrome (MERS) is a viral respiratory illness caused by a coronavirus. After the primary onset of MERS in Saudi Arabia, in September 2015 cases began to increase. The number of laboratory-affirmed cases by MERS-CoV in
Ahmadinejad, Fereshteh.   +3 more
core  

MERS-CoV at the animal–human interface: inputs on exposure pathways from an expert-opinion elicitation [PDF]

open access: yes, 2016
Nearly 4 years after the first report of the emergence of Middle-East respiratory syndrome Coronavirus (MERS-CoV) and nearly 1800 human cases later, the ecology of MERS-CoV, its epidemiology, and more than risk factors of MERS-CoV transmission between ...
Anna Funk   +9 more
core   +2 more sources

COVID-19 Infection: Implications for Perioperative and Critical Care Physicians. [PDF]

open access: yes, 2020
Healthcare systems worldwide are responding to Coronavirus Disease 2019 (COVID-19), an emerging infectious syndrome caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus. Patients with COVID-19 can progress from asymptomatic or
Greenland, John R   +3 more
core  

Home - About - Disclaimer - Privacy