Results 71 to 80 of about 10,659 (171)

Implementation of a Multiplex PCR Amplification System Combined With Next‐Generation Genome Sequencing to Decipher the Circulation of Human Coronavirus 229E Lineages in Southern France

Journal of Medical Virology, Volume 97, Issue 11, November 2025.
ABSTRACT Coronaviruses rapidly evolve and are prone to new virus emergence. Human coronavirus (HCoV)−229E is one of the seven coronaviruses (aside HCoV‐OC43, HCoV‐HKU1, HCoV‐NL63, SARS‐CoV, MERS‐CoV, SARS‐CoV‐2) causing respiratory infections in humans. Genomic data are very scarce for this virus.
Houmadi Hikmat, Justine Py, Céline Boschi, Emilie Burel, Lorlane Le Targa, Matthieu Million, Lucile Lesage, Aurélie Morand, Bernard La Scola, Philippe Colson   +9 more
wiley   +1 more source

A Narrative Review on the Recent Insights Into the Pathogenicity and Potential Role of Middle East Respiratory Syndrome Coronavirus (MERS‐CoV) in the Emergence of “Disease X”

Health Science Reports, Volume 8, Issue 10, October 2025.
ABSTRACT Background and Aims Following the end of the COVID‐19 global emergency, concern has shifted to “Disease X,” a hypothetical, highly transmissible, and deadly pathogen, and Middle East Respiratory Syndrome Coronavirus (MERS‐CoV) is a prime candidate for this. This review explores its epidemiology, mutations, transmission, and potential to become
Zubaier Ahmed, Kazi Milenur Rahman Prattay, Sabrina Sharmin, Fatema‐Tuz‐Zohora, Asef Raj, Forhad Bin Faruk, Bagdad Ahmed, Humair Bin Md Omer, Anika Awal Omi, Fazle Rabbi, Nasiba Binte Bahar, Sumiya Sharmin Mou, Mehedi Islam, Eshaba Karim, Md. Elias Al‐Mamun   +14 more
wiley   +1 more source

An alphacoronavirus polymerase structure reveals conserved replication factor functions

Nucleic Acids Research
Abstract Coronaviruses are a diverse subfamily of viruses containing pathogens of humans and animals. This subfamily of viruses replicates their RNA genomes using a core polymerase complex composed of viral non-structural proteins: nsp7, nsp8 and nsp12.
Thomas K Anderson, Peter J Hoferle, Kennan J Chojnacki, Kenneth W Lee, Joshua J Coon, Robert N Kirchdoerfer   +5 more
openaire   +2 more sources

Effects of SADS‐CoV accessory proteins NS3a, NS7a, and NS7b on viral pathogenicity: A multi‐omics investigation

iMetaOmics, Volume 2, Issue 3, September 2025.
This study has elucidated the role of three swine acute diarrhea syndrome coronavirus (SADS‐CoV) accessory proteins in influencing viral pathogenicity and preliminarily explored the host molecular targets and pathways affected by the NS3a, NS7a, and NS7b proteins of SADS‐CoV.
Xiaoling Yan, Xiaoli Zhang, Ling Zhou, Xiaoya Zhao, Qianniu Li, Tian Lan, Jun Fu, Jingyun Ma   +7 more
wiley   +1 more source

Investigations into SARS-CoV-2 and other coronaviruses on mink farms in France late in the first year of the COVID-19 pandemic.

PLoS ONE, 2023
Soon after the beginning of the COVID-19 pandemic in early 2020, the Betacoronavirus SARS-CoV-2 infection of several mink farms breeding American minks (Neovison vison) for fur was detected in various European countries. The risk of a new reservoir being
Marine Wasniewski, Franck Boué, Céline Richomme, Etienne Simon-Lorière, Sylvie Van der Werf, Flora Donati, Vincent Enouf, Yannick Blanchard, Véronique Beven, Estelle Leperchois, Bryce Leterrier, Sandrine Corbet, Meriadeg Le Gouil, Elodie Monchatre-Leroy, Evelyne Picard-Meyer   +14 more
doaj   +1 more source

Effectiveness of the Fungal Metabolite 3-O-Methylfunicone towards Canine Coronavirus in a Canine Fibrosarcoma Cell Line (A72)

Antibiotics, 2022
Canine coronavirus (CCoV), an alphacoronavirus, may cause self-limiting enteric disease in dogs, especially in puppies. The noteworthy plasticity of coronaviruses (CoVs) occurs through mutation and recombination processes, which sometimes generate new ...
Claudia Cerracchio, Valentina Iovane, Maria Michela Salvatore, Maria Grazia Amoroso, Hiba Dakroub, Marina DellaGreca, Rosario Nicoletti, Anna Andolfi, Filomena Fiorito   +8 more
doaj   +1 more source

Characterising alphacoronavirus phenotypic traits through diversity-driven selection of spike [PDF]

AbstractThe capacity for viruses to spillover from one host to another is dependent on their ability to bind to and enter cells from a new host. Using a computational approach that maximises phylogenetic diversity, we selected an optimal subset of 40 alphacoronavirus spike proteins, including the two human viruses NL63 and 229E, and characterised their
Giulia Gallo, Antonello Di Nardo, Aghnia Dewantari, Stephen C. Graham, Dalan Bailey   +4 more
openalex   +2 more sources

Understanding the Enigmatic Dance of Immune‐Mediated Viral Infections and Their Pathogenetic Mechanisms

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
This graphical representation illustrates the multifaceted nature of the immune response in viral infections, demonstrating both its protective and potentially harmful aspects. While a properly regulated immune reaction facilitates viral clearance and promotes general recovery, an overly robust or misdirected response—exemplified by Type III or Type IV
Muhammed Cesim Karabulut, Tuba Çiğdem Oğuzoğlu   +1 more
wiley   +1 more source

Bactericidal, Virucidal, and Biocompatible Properties of 3D Printed Materials Enhanced with Copper and Zinc Nanoparticles

Global Challenges, Volume 9, Issue 8, August 2025.
As population growth, urbanization, and climate change increase the spread of pathogens, hospital infections now affect 1 in 31 patients, costing billions annually. This study presents a new approach by integrating copper and zinc oxide nanoparticles into 3D‐printed materials.
Andrei‐Florin Sandu, Lauren Acton, Phillip Gould   +2 more
wiley   +1 more source

Longitudinal Survey of Coronavirus Circulation and Diversity in Insectivorous Bat Colonies in Zimbabwe

Viruses, 2022
Background: Studies have linked bats to outbreaks of viral diseases in human populations such as SARS-CoV-1 and MERS-CoV and the ongoing SARS-CoV-2 pandemic.
Vimbiso Chidoti, Hélène De Nys, Valérie Pinarello, Getrude Mashura, Dorothée Missé, Laure Guerrini, Davies Pfukenyi, Julien Cappelle, Ngoni Chiweshe, Ahidjo Ayouba, Gift Matope, Martine Peeters, Elizabeth Gori, Mathieu Bourgarel, Florian Liégeois   +14 more
doaj   +1 more source