Results 71 to 80 of about 13,277 (199)

Aberrant Cholesterol Metabolic Genes Regulation in a Negative Feedback Loop Induced by an Alphacoronavirus

Frontiers in Nutrition, 2022
Porcine epidemic diarrhea virus (PEDV) is an alphacoronavirus that causes acute inflammation and severe diarrhea in newborn piglets with a high mortality rate. Given that cholesterol is required for coronavirus infection in vitro, the role of endogenous cholesterol metabolism in regulating coronavirus infection and the mechanism behind it ought to be ...
Hao-Yu Liu, Haotian Gu, Huan Qu, Wenbin Bao, Yanhua Li, Demin Cai   +5 more
openaire   +3 more sources

Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats

Viruses, 2015
Bats are a reservoir for a diverse range of viruses, including coronaviruses (CoVs). To determine the presence of CoVs in French bats, fecal samples were collected between July and August of 2014 from four bat species in seven different locations around ...
Anne Goffard, Christine Demanche, Laurent Arthur, Claire Pinçon, Johan Michaux, Jean Dubuisson   +5 more
doaj   +1 more source

Successful in vitro propagation of feline coronavirus from clinically diagnosed feline infectious peritonitis cases using Vero cells: A potential model for future research

Veterinary Record Open, Volume 13, Issue 1, June 2026.
Abstract Background Feline coronavirus (FCoV) causes inapparent to progressive fatal feline infectious peritonitis (FIP) in domestic and wild cats, which affects multiple‐organ systems. Methods We investigated three clinically sick cats using different laboratory and molecular tests to diagnose and confirm FCoV and propagate the virus in Vero cell ...
Eaftekhar Ahmed Rana, Mahfuza Akther, Susan Beetson, Subir Sarker, Gabriele Rossi, Jasim M. Uddin   +5 more
wiley   +1 more source

Specific serology for emerging human coronaviruses by protein microarray [PDF]

, 2013
We present a serological assay for the specific detection of IgM and IgG antibodies against the emerging human coronavirus hCoV-EMC and the SARS-CoV based on protein microarray technology.
Bedrijfsvoering, Bosch, B J, de Sousa, R, Dep Infectieziekten Immunologie, Dittmer, U, Drosten, C, Godeke, G J, Haagmans, B, Koopmans, M, LS Virologie, Meyer, B, Mou, H, Müller, M A, Osterhaus, A, Reusken, C, Rottier, P, Schuurman, Nancy, van der Hoek, L   +17 more
core   +3 more sources

Mass‐Standardised Differential Antibody Binding to a Spectrum of SARS‐CoV‐2 Variant Spike Proteins: Wuhan, Alpha, Beta, Gamma, Delta, Omicron BA.1, BA.4/5, BA.2.75 and BA.2.12.1 Variants—Antibody Immunity Endotypes

Immunology, Volume 177, Issue 4, Page 798-809, April 2026.
Fully quantitative, mass‐standardised, antibody responses to ten SARS‐CoV‐2 variants show significant variation in immunity profiles or endotypes. The incidence of the complete response to all variants is significantly improved after three vaccinations.
Philip H. James‐Pemberton, Shivali Kohli, Jordan Twynham, Aaron C. Westlake, Alex Antill, Rouslan V. Olkhov, Andrew M. Shaw   +6 more
wiley   +1 more source

Hypericin Inhibit Alpha-Coronavirus Replication by Targeting 3CL Protease

Viruses, 2021
The porcine epidemic diarrhea virus (PEDV) is an Alphacoronavirus (α-CoV) that causes high mortality in infected piglets, resulting in serious economic losses in the farming industry. Hypericin is a dianthrone compound that has been shown as an antiviral
Yue Zhang, Huijie Chen, Mengmeng Zou, Rick Oerlemans, Changhao Shao, Yudong Ren, Ruili Zhang, Xiaodan Huang, Guangxing Li, Yingying Cong   +9 more
doaj   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, Volume 36, Issue 26, 30 March 2026.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Circulation of Alphacoronavirus, Betacoronavirus and Paramyxovirus in Hipposideros bat species in Zimbabwe

Infection, Genetics and Evolution, 2018
(Uploaded by Plazi for the Bat Literature Project) Bats carry a great diversity of zoonotic viruses with a high-impact on human health and livestock. Since the emergence of new coronaviruses and paramyxoviruses in humans (e.g. Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Nipah virus), numerous studies clearly established that bats can ...
Bourgarel, Mathieu, Pfukenyi, Davies, Boué, Vanina, Talignani, Loïc, Chiweshe, Ngoni, Diop, Fode, Caron, Alexandre, Matope, Gift, Missé, Dorothée, Liegeois, Florian   +9 more
openaire   +5 more sources

Diversity and spillover risk of swine acute diarrhea syndrome and related coronaviruses in China and Southeast Asia

mBio
Bats are the reservoir hosts of emerging coronaviruses (CoVs) affecting human and livestock health. We assessed the diversity, evolution, and geographic distribution of two alphacoronaviruses (subgenus Rhinacovirus) with considerable potential for ...
Alice Latinne, Li-Biao Zhang, Cadhla Firth, Guangjian Zhu, Kevin J. Olival, Cecilia A. Sánchez, Shirley Chen, Noam Ross, Hongying Li, Aleksei A. Chmura, Peter Daszak   +10 more
doaj   +1 more source

Detection of Alpha- and Betacoronaviruses in Frugivorous and Insectivorous Bats in Nigeria

Pathogens, 2022
The rise of bat-associated zoonotic viruses necessitates a close monitoring of their natural hosts. Since the detection of severe acute respiratory syndrome coronavirus (SARS-CoV), it is evident that bats are vital reservoirs of coronaviruses (CoVs).
Uwem George, Oluwadamilola George, Arthur Oragwa, Babatunde Motayo, Joshua Kamani, Andrew Adamu, Oluyomi Sowemimo, Richard Adeleke, Samson Abalaka, Nuhu Sani, Judith Oguzie, Philomena Eromon, Onikepe Folarin, Anise Happi, Isaac Komolafe, Christian Happi   +15 more
doaj   +1 more source