Impact of BoLA-DRB3 Polymorphisms on Clonality of Bovine Leukaemia Virus-Infected Cells of Cattle With Lymphoma. [PDF]
HLAABSTRACT Bovine leukaemia virus (BLV) infects cattle, integrates into the host genome as a provirus, and induces a persistent infection that remains asymptomatic but can cause leukaemia/lymphoma. Most BLV‐infected cell clones are created by massive depletion, and a few of these infected cell clones expand through the mitotic cycle, leading to the onset
Fukushi N +10 more
europepmc +2 more sources
Unique Structure and Distinctive Properties of the Ancient and Ubiquitous Gamma-Type Envelope Glycoprotein [PDF]
Viruses, 2023 Welkin E Johnson
exaly +2 more sources
Detection of lymphoproliferative disease virus in domestic and wild turkeys through RNAscope in situ hybridization and immunohistochemistry [PDF]
Journal of Veterinary Diagnostic InvestigationAndrew B Allison +2 more
exaly +2 more sources
mLife, Volume 2, Issue 2, Page 201-208, June 2023., 2023 Abstract Mammalian endogenous retroviruses (ERVs) are ancient retroviruses that have been integrated into genomes. ERVs were believed to be inactive until the discovery of ERV transcription in the mouse genome. However, the transcription level and function of ERV elements in mammalian genomes are not well understood.
Zheng Li +5 more
wiley +1 more source
CAR‐NK cells: the next wave of cellular therapy for cancer
Clinical &Translational Immunology, Volume 10, Issue 4, 2021., 2021 NK cells can be derived from various sources (PB, UCB, HSC, iPSC, NK cell lines) and can be engineered to express a chimeric antigen receptor (CAR) to target various surface antigens on cancer cells. These CAR‐NK cells can be used as off‐the‐shelf adoptive cellular therapy to treat patients with various malignancies.
May Daher +3 more
wiley +1 more source
Mediators of Inflammation, Volume 2021, Issue 1, 2021., 2021 The aim of this study was to better understand the sequence characteristics and immune responses in avian leukosis virus subgroup J (ALV‐J) infected yellow chicken flocks in South China. We isolated four strains of ALV‐J virus from these flocks, which were then identified by several methods, including subtype‐specific polymerase chain reaction (PCR ...
Qihong Zhang +7 more
wiley +1 more source
Seroprevalence of avian leukosis virus in local chickens in five live bird markets, Kaduna metropolis, North-western Nigeria [PDF]
, 2022 Avian leukosis virus is recognized as an important viral pathogen in the poultry industry, resulting in salient severe economic losses due to reduced production, uneven flock growth rates, reduced growth, and immunosuppression which predispose affected ...
Bakam, J.D. +5 more
core +2 more sources
Alpharetroviral Vectors: From a Cancer-Causing Agent to a Useful Tool for Human Gene Therapy [PDF]
, 2014 Gene therapy using integrating retroviral vectors has proven its effectiveness in several clinical trials for the treatment of inherited diseases and cancer.
Labenski, Verena +2 more
core +6 more sources
Biochemical Characterization of Novel Retroviral Integrase Proteins [PDF]
, 2013 Integrase is an essential retroviral enzyme, catalyzing the stable integration of reverse transcribed DNA into cellular DNA. Several aspects of the integration mechanism, including the length of host DNA sequence duplication flanking the integrated ...
Ballandras-Colas, Allison +4 more
core +4 more sources
Interplay between the alpharetroviral Gag protein and SR proteins SF2 and SC35 in the nucleus [PDF]
, 2015 Retroviruses are positive-sense, single-stranded RNA viruses that reverse transcribe their RNA genomes into double-stranded DNA for integration into the host cell chromosome.
Breanna L. Rice +4 more
core +2 more sources