Results 11 to 20 of about 787 (88)
Genome-wide characterization and comparison of endogenous retroviruses among 3 duck reference genomes [PDF]
Poultry Science: Endogenous retroviruses (ERV) are viral genomes integrated into the host genome and can be stably inherited. Although ERV sequences have been reported in some avian species’ genome, the duck endogenous retroviruses (DERV) genome has yet to be ...
Yuan Bai +14 more
doaj +2 more sources
Frontiers in Veterinary Science, 2022 Avian leukosis caused by avian leukosis virus (ALV), belonging to the genus Alpharetrovirus of the family Retroviridae, is associated with benign and malignant tumors in hemopoietic cells in poultry.
Venugopal Nair, Yongxiu Yao, Na Tang
exaly +3 more sources
Virology, 2006 The Rous sarcoma virus (RSV) Gag polyprotein is the only protein required for virus assembly and release. We previously found that deletion of either one of the two Cys-His (CH) motifs in the RSV nucleocapsid (NC) protein did not abrogate Gag-Gag interactions, RNA binding, or packaging but greatly reduced virus production (E-G. Lee, A.
Maxine L Linial, Eun-Gyung Lee
exaly +3 more sources
Current knowledge on the epidemiology and prevention of Avian leukosis virus in China [PDF]
Poultry Science: Avian leukosis virus (ALV) is an enveloped retrovirus with a single-stranded RNA genome, belonging to the genus Alpharetrovirus within the family Retroviridae.
Lei Tan +9 more
doaj +2 more sources
Protease-mediated maturation of M-PMV reverse transcriptase into a functional heterodimer. [PDF]
Protein SciAbstract Reverse transcriptase (RT) of retroviruses orchestrates viral replication, yet its structural diversity remains poorly understood. Well‐studied RTs, such as those from HIV‐1, murine leukemia virus, and avian myeloblastosis virus, were characterized decades ago, but less prominent retroviruses have escaped detailed analysis.
Kapisheva M +6 more
europepmc +2 more sources
Detection of lymphoproliferative disease virus in domestic and wild turkeys through RNAscope in situ hybridization and immunohistochemistry [PDF]
Journal of Veterinary Diagnostic InvestigationNicole Nemeth +2 more
exaly +2 more sources
mLife, Volume 2, Issue 2, Page 201-208, June 2023., 2023 Abstract Mammalian endogenous retroviruses (ERVs) are ancient retroviruses that have been integrated into genomes. ERVs were believed to be inactive until the discovery of ERV transcription in the mouse genome. However, the transcription level and function of ERV elements in mammalian genomes are not well understood.
Zheng Li +5 more
wiley +1 more source
CAR‐NK cells: the next wave of cellular therapy for cancer
Clinical &Translational Immunology, Volume 10, Issue 4, 2021., 2021 NK cells can be derived from various sources (PB, UCB, HSC, iPSC, NK cell lines) and can be engineered to express a chimeric antigen receptor (CAR) to target various surface antigens on cancer cells. These CAR‐NK cells can be used as off‐the‐shelf adoptive cellular therapy to treat patients with various malignancies.
May Daher +3 more
wiley +1 more source
Gene Therapy for Primary Immunodeficiency
HemaSphere, Volume 5, Issue 1, January 2021., 2021 Over the past 3 decades, there has been significant progress in refining gene therapy technologies and procedures. Transduction of hematopoietic stem cells ex vivo using lentiviral vectors can now create a highly effective therapeutic product, capable of reconstituting many different immune system dysfunctions when reinfused into patients.
Benjamin C. Houghton, Claire Booth
wiley +1 more source
Cardiac pathology and molecular epidemiology by avian leukosis viruses in Japan. [PDF]
PLoS ONE, 2014 Epidemiological studies suggest that retroviruses, including human immunodeficiency virus type 1, are associated with cardiomyopathy and myocarditis, but a causal relationship remains to be established.
Sayuri Nakamura +7 more
doaj +1 more source