Perinatal Gene Transfer to the Liver [PDF]
, 2011 The liver acts as a host to many functions hence raising the possibility that any one may be compromised by a single gene defect. Inherited or de novo mutations in these genes may result in relatively mild diseases or be so devastating that death within
Buckley, SM +6 more
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The interferon-inducible antiviral protein Daxx is not essential for interferon-mediated protection against avian sarcoma virus [PDF]
, 2014 BACKGROUND: The antiviral protein Daxx acts as a restriction factor of avian sarcoma virus (ASV; Retroviridae) in mammalian cells by promoting epigenetic silencing of integrated proviral DNA.
Anna Skalka +5 more
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Dimer Interface Organization is a Main Determinant of Intermonomeric Interactions and Correlates with Evolutionary Relationships of Retroviral and Retroviral-Like Ddi1 and Ddi2 Proteases [PDF]
, 2020 L
Miczi, Márió +2 more
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Biotechnology and Bioengineering, Volume 117, Issue 2, Page 466-485, February 2020., 2020 Endogenous retroviruses in Chinese hamster ovary cells were characterized at the genome, transcriptome and viral particle level. Following CRISPR‐mediated mutagenesis, the authors identified a single endogenous retrovirus locus responsible for the budding of viral particles into the cell supernatant.
Pierre‐Olivier Duroy +11 more
wiley +1 more source
The roles of lipids and nucleic acids in HIV-1 assembly [PDF]
, 2014 During HIV-1 assembly, precursor Gag (PrGag) proteins are delivered to plasma membrane (PM) assembly sites, where they are triggered to oligomerize and bud from cells as immature virus particles.
Ayna Alfadhli, Eric Barklis
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Metagenomics screening of viruses in Arusha, north Tanzania: a one health perspective across wild rodents, domestic dogs and humans [PDF]
, 2023 Background: One of the most significant and perilous challenges faced by African societies, including Tanzania, is the public health threat posed by zoonotic viruses.
Chengula, Augustino +4 more
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A metagenomic comparison of endemic viruses from broiler chickens with runting stunting syndrome and from normal birds [PDF]
, 2016 Runting-stunting syndrome (RSS) in broiler chickens is an enteric disease that causes significant economic losses to poultry producers worldwide due to elevated feed conversion ratios, decreased body weight during growth, and excessive culling.
Devaney, Ryan +4 more
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Key determinants of target DNA recognition by retroviral intasomes [PDF]
, 2015 BACKGROUND: Retroviral integration favors weakly conserved palindrome sequences at the sites of viral DNA joining and generates a short (4–6 bp) duplication of host DNA flanking the provirus.
Ballandras-Colas, A +4 more
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Acquiring Resistance Against a Retroviral Infection via CRISPR/Cas9 Targeted Genome Editing in a Commercial Chicken Line [PDF]
, 2020 Genome editing technology provides new possibilities for animal breeding and aid in understanding host-pathogen interactions. In poultry, retroviruses display one of the most difficult pathogens to control by conventional strategies such as vaccinations.
Bartsch, Denise +11 more
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Birch pollen allergen immunotherapy reprograms nasal epithelial transcriptome and recovers microbial diversity [PDF]
, 2019 Peer ...
Dhaygude, Kishor +12 more
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