Results 21 to 30 of about 787 (88)

Phylogenetic Analysis of ALV‐J Associated with Immune Responses in Yellow Chicken Flocks in South China

Mediators of Inflammation, Volume 2021, Issue 1, 2021., 2021
The aim of this study was to better understand the sequence characteristics and immune responses in avian leukosis virus subgroup J (ALV‐J) infected yellow chicken flocks in South China. We isolated four strains of ALV‐J virus from these flocks, which were then identified by several methods, including subtype‐specific polymerase chain reaction (PCR ...
Qihong Zhang, Guodong Mo, Tingting Xie, Zihao Zhang, Huali Fu, Ping Wei, Xiquan Zhang, Shuai Chen   +7 more
wiley   +1 more source

Impact of BoLA-DRB3 Polymorphisms on Clonality of Bovine Leukaemia Virus-Infected Cells of Cattle With Lymphoma. [PDF]

HLA
ABSTRACT Bovine leukaemia virus (BLV) infects cattle, integrates into the host genome as a provirus, and induces a persistent infection that remains asymptomatic but can cause leukaemia/lymphoma. Most BLV‐infected cell clones are created by massive depletion, and a few of these infected cell clones expand through the mitotic cycle, leading to the onset
Fukushi N, Yamanaka MP, Matsuura R, Watanuki S, Saito S, Matsumoto Y, Fukumoto K, Hosomichi K, Wang J, Takeshima SN, Aida Y.   +10 more
europepmc   +2 more sources

Biochemical characterization of novel retroviral integrase proteins. [PDF]

PLoS ONE, 2013
Integrase is an essential retroviral enzyme, catalyzing the stable integration of reverse transcribed DNA into cellular DNA. Several aspects of the integration mechanism, including the length of host DNA sequence duplication flanking the integrated ...
Allison Ballandras-Colas, Hema Naraharisetty, Xiang Li, Erik Serrao, Alan Engelman   +4 more
doaj   +1 more source

Characterization and mutagenesis of Chinese hamster ovary cells endogenous retroviruses to inactivate viral particle release

Biotechnology and Bioengineering, Volume 117, Issue 2, Page 466-485, February 2020., 2020
Endogenous retroviruses in Chinese hamster ovary cells were characterized at the genome, transcriptome and viral particle level. Following CRISPR‐mediated mutagenesis, the authors identified a single endogenous retrovirus locus responsible for the budding of viral particles into the cell supernatant.
Pierre‐Olivier Duroy, Sandra Bosshard, Emanuel Schmid‐Siegert, Samuel Neuenschwander, Ghislaine Arib, Philippe Lemercier, Jacqueline Masternak, Lucien Roesch, Flavien Buron, Pierre‐Alain Girod, Ioannis Xenarios, Nicolas Mermod   +11 more
wiley   +1 more source

Orchestrating the Selection and Packaging of Genomic RNA by Retroviruses: An Ensemble of Viral and Host Factors

Viruses, 2016
Infectious retrovirus particles contain two copies of unspliced viral RNA that serve as the viral genome. Unspliced retroviral RNA is transcribed in the nucleus by the host RNA polymerase II and has three potential fates: (1) it can be spliced into ...
Rebecca J. Kaddis Maldonado, Leslie J. Parent   +1 more
doaj   +1 more source

Interplay between the alpharetroviral Gag protein and SR Proteins SF2 and SC35 in the nucleus

Frontiers in Microbiology, 2015
Retroviruses are positive-sense, single-stranded RNA viruses that reverse transcribe their RNA genomes into double-stranded DNA for integration into the host cell chromosome.
Breanna L. Rice, Rebecca J. Kaddis, Matthew S. Stake, Timothy L. Lochmann, Leslie J. Parent   +4 more
doaj   +1 more source

Oxidative Stress in Poultry: Lessons from the Viral Infections

Oxidative Medicine and Cellular Longevity, Volume 2018, Issue 1, 2018., 2018
Reactive species (RS), generally known as reactive oxygen species (ROS) and reactive nitrogen species (RNS), are produced during regular metabolism in the host and are required for many cellular processes such as cytokine transcription, immunomodulation, ion transport, and apoptosis.
Zaib Ur Rehman, Chunchun Meng, Yingjie Sun, Anum Safdar, Riaz Hussain Pasha, Muhammad Munir, Chan Ding, Angel Catalá   +7 more
wiley   +1 more source

Isolation and Metagenomic Identification of Avian Leukosis Virus Associated with Mortality in Broiler Chicken

Advances in Virology, Volume 2016, Issue 1, 2016., 2016
Avian leukosis virus (ALV) belongs to the family Retroviridae and causes considerable economic losses to the poultry industry. Following an outbreak associated with high mortality in a broiler flock in northern part of Malaysia, kidney tissues from affected chickens were submitted for virus isolation and identification in chicken embryonated egg and ...
Faruku Bande, Siti Suri Arshad, Abdul Rahman Omar, Finn S. Pedersen   +3 more
wiley   +1 more source

Complex Codon Usage Pattern and Compositional Features of Retroviruses

Computational and Mathematical Methods in Medicine, Volume 2013, Issue 1, 2013., 2013
Retroviruses infect a wide range of organisms including humans. Among them, HIV‐1, which causes AIDS, has now become a major threat for world health. Some of these viruses are also potential gene transfer vectors. In this study, the patterns of synonymous codon usage in retroviruses have been studied through multivariate statistical methods on ORFs ...
Sourav RoyChoudhury, Debaprasad Mukherjee, Kazuhisa Nishizawa   +2 more
wiley   +1 more source

A Genome‐Wide Analysis of RNA Pseudoknots That Stimulate Efficient −1 Ribosomal Frameshifting or Readthrough in Animal Viruses

BioMed Research International, Volume 2013, Issue 1, 2013., 2013
Programmed −1 ribosomal frameshifting (PRF) and stop codon readthrough are two translational recoding mechanisms utilized by some RNA viruses to express their structural and enzymatic proteins at a defined ratio. Efficient recoding usually requires an RNA pseudoknot located several nucleotides downstream from the recoding site.
Xiaolan Huang, Qiang Cheng, Zhihua Du, Marcelo A. Soares   +3 more
wiley   +1 more source