New insights into control of arbovirus replication and spread by insect RNA interference pathways [PDF]
Arthropod-borne (arbo) viruses are transmitted by vectors, such as mosquitoes, to susceptible vertebrates. Recent research has shown that arbovirus replication and spread in mosquitoes is not passively tolerated but induces host responses to control ...
Andersson +55 more
core +3 more sources
Global Warming Affects the Pathogenesis of Important Fish Diseases in European Aquaculture
The effect of global warming on pathogens and their fish hosts that could exacerbate the negative outcomes for aquaculture. Changes in farming practices and the development of innovative mitigation tools may prove essential to cope with the effects and impacts of rising water temperatures on fish diseases in Europe.
George Rigos +7 more
wiley +1 more source
Alphavirus vectors for cancer therapy
Alphaviruses contain a single strand RNA genome that can be easily modified to express heterologous genes at very high levels in a broad variety of cells, including tumor cells. Alphavirus vectors can be used as viral particles containing a packaged vector RNA, or directly as nucleic acids in the form of RNA or DNA. In the latter case alphavirus RNA is
Jose I, Quetglas +5 more
openaire +2 more sources
Use of a lambda gt11 expression library to localize a neutralizing antibody-binding site in glycoprotein E2 of Sindbis virus [PDF]
The Sindbis virus envelope contains two species of integral membrane glycoproteins, E1 and E2. These proteins form heterodimers, and three dimeric units assemble to form spikes incorporated into the viral surface which play an important role in the ...
Strauss, James H., Wang, Kang-Sheng
core +1 more source
Interferon-Gamma Modulation of the Local T Cell Response to Alphavirus Encephalomyelitis
Infection of mice with Sindbis virus (SINV) provides a model for examining the role of the immune response to alphavirus infection of the central nervous system (CNS).
Victoria K. Baxter, D. Griffin
semanticscholar +1 more source
Emerging Challenges and Advances in Porcine Circovirus: A Decade in Review
Over the past decade, porcine circoviruses (PCVs) have continued to pose a significant threat to global swine health, and pivotal discoveries have significantly reshaped our understanding of their biology and control. Extensive genomic surveillance has expanded porcine circovirus 2 (PCV2) genotyping from four to at least eight lineages, with PCV2d now ...
Jiawei Zheng +4 more
wiley +1 more source
Semliki Forest virus induced, immune mediated demyelination: the effect of irradiation [PDF]
International audienceThe Dark Energy Camera has captured a large set of images as part of Science Verification (SV) for the Dark Energy Survey (DES). The SV footprint covers a large portion of the outer Large Magellanic Cloud (LMC), providing photometry
Abbott, T. M. C. +54 more
core +4 more sources
Detection and Characterization of Sindbis Virus Genotype IV in Mosquitoes From Slovenia
Mosquitoes play a crucial role as vectors of disease pathogens and are among the most socioeconomically important animals in the world. Medically important arboviruses include the Sindbis virus (SINV), which causes chills, skin rashes, and joint pain. Endemic in northern Europe, SINV has been increasingly detected in central Europe. The main objectives
Patricija Pozvek +11 more
wiley +1 more source
Alphavirus infections are transmitted by mosquitoes, but the mode of transmission for Mycobacterium ulcerans, which causes Buruli ulcer, is contested. Using notification data for Victoria, Australia, during 2017–2022, adjusted for incubation period, we ...
Andrew H. Buultjens +5 more
doaj +1 more source
Alphavirus Infection: Host Cell Shut-Off and Inhibition of Antiviral Responses
Alphaviruses cause debilitating disease in humans and animals and are transmitted by blood-feeding arthropods, typically mosquitoes. With a traditional focus on two models, Sindbis virus and Semliki Forest virus, alphavirus research has significantly ...
Jelke J. Fros, Gorben P. Pijlman
doaj +1 more source

