Results 101 to 110 of about 15,159 (204)

Nonreciprocity in CHIKV and MAYV Vaccine-Elicited Protection

Vaccines
Chikungunya virus (CHIKV) is a pathogenic arthritogenic alphavirus responsible for large-scale human epidemics for which a vaccine was recently approved for use.
Whitney C. Weber, Takeshi F. Andoh, Craig N. Kreklywich, Zachary J. Streblow, Michael Denton, Magdalene M. Streblow, John M. Powers, Gauthami Sulgey, Samuel Medica, Igor Dmitriev, David T. Curiel, Nicole N. Haese, Daniel N. Streblow   +12 more
doaj   +1 more source

A Universal Next-Generation Sequencing Protocol To Generate Noninfectious Barcoded cDNA Libraries from High-Containment RNA Viruses

mSystems, 2016
Several biosafety level 3 and/or 4 (BSL-3/4) pathogens are high-consequence, single-stranded RNA viruses, and their genomes, when introduced into permissive cells, are infectious. Moreover, many of these viruses are select agents (SAs), and their genomes
Lindsey A. Moser, Lisbeth Ramirez-Carvajal, Vinita Puri, Steven J. Pauszek, Krystal Matthews, Kari A. Dilley, Clancy Mullan, Jennifer McGraw, Michael Khayat, Karen Beeri, Anthony Yee, Vivien Dugan, Mark T. Heise, Matthew B. Frieman, Luis L. Rodriguez, Kristen A. Bernard, David E. Wentworth, Timothy B. Stockwell, Reed S. Shabman   +18 more
doaj   +1 more source

Src Family Kinase Inhibitors Block Translation of Alphavirus Subgenomic mRNAs

, 2019
Alphaviruses are arthropod-transmitted RNA viruses that can cause arthralgia, myalgia, and encephalitis in humans. Since the role of cellular kinases in alphavirus replication is unknown, we profiled kinetic changes in host kinase abundance and ...
DeFilippis, Victor R., Graves, Lee, Streblow, Daniel, Morrison, Thomas E., Heise, Mark T., Smith, Patricia, Kreklywich, Craig N., Streblow, Daniel N., Moorman, Nathaniel, Broeckel, Rebecca, Sarkar, Sanjay, Totonchy, Jennifer, May, Nicholas A.   +12 more
core   +1 more source

ANALISIS MODEL MATEMATIKA PENGUJI EFEKTIVITAS ONCOLYTIC PADA ALPHAVIRUS [PDF]

, 2019
Kanker merupakan salah satu penyakit penyebab kematian dengan jumlah terbesar di seluruh dunia. Oncolotyc virotherapy adalah metode pengobatan yang menggunakan replikasi virus sebagai agen antineoplastik yang selektif, yang masih dalam tahap ...
RAHMAWATI NUR FADZILLAH, 081211233030
core  

siRNA Screen Identifies Trafficking Host Factors that Modulate Alphavirus Infection.

, 2016
Little is known about the repertoire of cellular factors involved in the replication of pathogenic alphaviruses. To uncover molecular regulators of alphavirus infection, and to identify candidate drug targets, we performed a high-content imaging-based ...
Gianluca Pegoraro, Chih-Yuan Chiang, Sina Bavari (154739), Christopher L Cooper, Jeremiah C. Clester (348526), Lián Dǒng (2584498), Jens H Kuhn, Mei G Sun, Rouzbeh Zamani (2584486), David P Langan, David P. Langan (2584501), Krishna Kota (348527), Jens H. Kuhn (200537), Gianluca Pegoraro (182347), Krishna Kota, Lián D Ng, Lucas Jozwick (2584483), Rouzbeh Zamani, Kathleen A Kuehl, Shu Qìng Yú, Shuǐqìng Yú (2220817), Duane Courier, Yíngyún Caì (2220820), Robin Burk (2220811), Yíngyún Caì, Sheli R Radoshitzky, Knashka Underwood, Robin Burk, Sheli R. Radoshitzky (233641), Sina Bavari, Xiǎolì Chī (2584495), Christopher L. Cooper (2584507), Mei G. Sun (2584510), Kathleen A. Kuehl (2584489), Jeremiah C Clester, Duane Courier (2584504), Knashka Underwood (2584480), Xi Olì Chī, Chih-Yuan Chiang (2584492), Lucas Jozwick   +39 more
core   +1 more source

Alternative cell line for the isolation of salmonid alphavirus-1 [PDF]

, 2009
Salmonid alphavirus (SAV) has recently become an economically important pathogen in salmonid aquaculture in Europe. Subtype SAV-1 causes salmon pancreas disease (SPD) in Atlantic salmon in Scotland and Ireland, and was first isolated on Chinook salmon ...
Adams, Alexandra, Richards, Randolph, Thompson, Kimberly, Herath, Tharangani, Costa, Janina Z   +4 more
core  

Interactions involved in pH protection of the alphavirus fusion protein

, 2015
The alphavirus membrane protein E1 mediates low pH-triggered fusion of the viral and endosome membranes during virus entry. During virus biogenesis E1 associates as a heterodimer with the transmembrane protein p62. Late in the secretory pathway, cellular
Fields, Whitney, Kielian, Margaret
core   +1 more source

Evaluating anti-CHIK IgM and qualitative RT-PCR for diagnosing chikungunya in hospitalized patients: A comparative analysis of diagnostic efficacy

Journal of Vector Borne Diseases
Background & objectives: Chikungunya virus (CHIKV) is an alphavirus characterized by a positive-sense, single-stranded RNA genome, and it is transmitted primarily by Aedes mosquitoes.
Mohd Afzal, Abhishek Sharma, Ashok Kumar Sah, M Chandrasekar   +3 more
doaj   +1 more source

Multivariate analysis of alphavirus seropositivity and ONNV-only seropositivity.

, 2015
Multivariate analysis of alphavirus seropositivity and ONNV-only seropositivity.
Charles H. King (78462), Erin Borland (689701), Crystal Y. Teng (689703), Ann M. Powers (105700), Sarah Pfeil (689702), Eric M. Muchiri (119767), Julie Brichard (689700), Francis M. Mutuku (386408), Peter L. Mungai (119766), Tamara Banda (689699), A. Desiree LaBeaud (2279977), Uriel Kitron (119769), Ginny Gildengorin (209363), Kristin Long (689704), Mark Heise (67117)   +14 more
core   +1 more source

Investigating the Role of Sphingosine Kinases During Alphavirus Infection

, 2022
Several alphaviruses, critical human pathogens, have re-emerged in recent years. Alphaviruses are found on all continents and infect both invertebrates and vertebrates, including some aquatic animals.
Oyewole, Opeoluwa
core