Results 91 to 100 of about 15,159 (204)

Alphavirus-host interactions : how to unravel the proviral activity of G3BP

open access: yes, 2019
The genus Alphavirus belongs to the virus family Togaviridiae, a group of arthropod-borne enveloped RNA viruses with single-stranded, positive-sense genome.
Benjamin Götte (18672085)
core  

VCP/p97 Is a Proviral Host Factor for Replication of Chikungunya Virus and Other Alphaviruses

open access: yesFrontiers in Microbiology, 2019
The evolutionarily conserved AAA+ ATPase valosin-containing protein (VCP) was previously shown to be a proviral host factor for several viruses from different viral families such as Flaviviridae, Picornaviridae, and Herpesviridae. VCP was shown to affect
Guillaume Carissimo   +10 more
doaj   +1 more source

The Role of the Opal Termination Codon in Alphavirus Pathogenesis

open access: yes, 2018
Alphaviruses are members of the Togaviridae family of viruses. These viruses are arboviruses, most often transmitted by a mosquito host. Serious outbreaks of alphavirus infection occur worldwide and affect millions of people. Currently, the greatest risk
Jones, Jennifer
core   +1 more source

Advances in Alphavirus and Flavivirus Research

open access: yesViruses
Newly emerging viruses, primarily zoonotic or vector-borne, pose a persistent threat to public health and have led to outbreaks of global concern [...]
Kim, YC, Reyes-Sandoval, A
openaire   +4 more sources

nsP3-FXR co-condensation enables alphavirus replication and reveals a targetable alphavirus vulnerability

open access: yesCell Reports
Summary: Alphaviruses are mosquito-borne RNA viruses that pose a significant threat to humans, with risks worsened by global warming. Non-structural protein 3 (nsP3) is critical for alphavirus infection, yet its precise roles remain poorly defined. Using
Yifan Xie   +13 more
doaj   +1 more source

Characteristics of Madariaga and Venezuelan Equine Encephalitis Virus Infections, Panama

open access: yesEmerging Infectious Diseases
Madariaga virus (MADV) and Venezuelan equine encephalitis virus (VEEV) are emerging arboviruses affecting rural and remote areas of Latin America. However, clinical and epidemiologic reports are limited, and outbreaks are occurring at an increasing ...
Luis Felipe Rivera   +24 more
doaj   +1 more source

Sindbis Virus Infection in Resident Birds, Migratory Birds, and Humans, Finland

open access: yesEmerging Infectious Diseases, 2008
Sindbis virus (SINV), a mosquito-borne virus that causes rash and arthritis, has been causing outbreaks in humans every seventh year in northern Europe.
Satu Kurkela   +9 more
doaj   +1 more source

PLoS One [PDF]

open access: yes
We established a rapid, specific technique for detecting alphaviruses using a replicon-defective reporter gene assay derived from the Sindbis virus XJ-160.

core  

Alphavirus replicon approach to promoterless analysis of IRES elements

open access: yes, 2007
Here we describe a system for promoterless analysis of putative internal ribosome entry site (IRES) elements using an alphavirus (family Togaviridae) replicon vector.
Owens, G.   +7 more
core   +1 more source

Disruption of the Opal Stop Codon Attenuates Chikungunya Virus-Induced Arthritis and Pathology

open access: yesmBio, 2017
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus responsible for several significant outbreaks of debilitating acute and chronic arthritis and arthralgia over the past decade.
Jennifer E. Jones   +12 more
doaj   +1 more source

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