Results 121 to 130 of about 27,933 (291)

Interferon-Gamma Modulation of the Local T Cell Response to Alphavirus Encephalomyelitis

Viruses, 2020
Infection of mice with Sindbis virus (SINV) provides a model for examining the role of the immune response to alphavirus infection of the central nervous system (CNS).
Victoria K. Baxter, D. Griffin
semanticscholar   +1 more source

Behaviour and Dispersal of Mobile Salmon Lice When Detached From the Host

Journal of Fish Diseases, Volume 48, Issue 11, November 2025.
ABSTRACT Sea lice can flourish when salmon are farmed in open sea‐cages, necessitating treatments to control outbreaks and reduce larval export. However, mobile ectoparasitic stages can be dislodged during crowding or other procedures, and potentially reinfest farmed or wild fish.
Luke T. Barrett, Mari F. Jensen, Sussie Dalvin, Frode Oppedal   +3 more
wiley   +1 more source

Mosquitoes as Vectors of Mycobacterium ulcerans Based on Analysis of Notifications of Alphavirus Infection and Buruli Ulcer, Victoria, Australia

Emerging Infectious Diseases
Alphavirus infections are transmitted by mosquitoes, but the mode of transmission for Mycobacterium ulcerans, which causes Buruli ulcer, is contested. Using notification data for Victoria, Australia, during 2017–2022, adjusted for incubation period, we ...
Andrew H. Buultjens, Ee Laine Tay, Aidan Yuen, N. Deborah Friedman, Timothy P. Stinear, Paul D.R. Johnson   +5 more
doaj   +1 more source

VCP/p97 Is a Proviral Host Factor for Replication of Chikungunya Virus and Other Alphaviruses

Frontiers in Microbiology, 2019
The evolutionarily conserved AAA+ ATPase valosin-containing protein (VCP) was previously shown to be a proviral host factor for several viruses from different viral families such as Flaviviridae, Picornaviridae, and Herpesviridae. VCP was shown to affect
Guillaume Carissimo, Yi-Hao Chan, Yi-Hao Chan, Age Utt, Tze-Kwang Chua, Farhana Abu Bakar, Farhana Abu Bakar, Andres Merits, Lisa F. P. Ng, Lisa F. P. Ng, Lisa F. P. Ng   +10 more
doaj   +1 more source

SNAP-tagged Chikungunya Virus Replicons Improve Visualisation of Non-Structural Protein 3 by Fluorescence Microscopy [PDF]

, 2017
Chikungunya virus (CHIKV), a mosquito-borne alphavirus, causes febrile disease, muscle and joint pain, which can become chronic in some individuals. The non-structural protein 3 (nsP3) plays essential roles during infection, but a complete understanding ...
A Gautier, A Ivanova, A Salonen, A Utt, AC Register, AE Firth, B Meason, B Thaa, BM Kummerer, C Li, C Schilte, C Smalley, CB Muller, CJ Sheppard, D Moradpour, D Ross-Thriepland, DY Kim, E Born van den, E Frolova, E Herker, E Park, EI Frolova, F Chaumont de, FE Scholte, FE Scholte, G Camus, G Lukinavicius, G Shi, G Shin, G Yang, GP Li, H Gong, H Malet, H Nakabayashi, H Tourriere, H Vihinen, H Vihinen, H Wang, HJ Yang, I De, I Frolov, IM Cristea, J Peranen, JE Snyder, JH Strauss, JJ Fros, JJ Fros, K Bojkowska, K Onomoto, K Tsetsarkin, KM Dean, L Eckei, L Pohjala, M Eckhardt, M Neuvonen, M Neuvonen, M Ruiz-Guillen, MD Panas, MD Panas, MD Panas, ML Rajamaki, MW LaStarza, N Tamberg, NF Rose, NJ Foy, P Bieling, P Laakkonen, P Targett-Adams, R Abdelnabi, R Gorchakov, RL McPherson, S Martin, S Mueller, SC Weaver, T Ahola, T Fujimoto, T Klein, WR Hardy, Y Fujimoto, Y Miyanari, YF Wang   +80 more
core   +1 more source

Differential Alphavirus Defective RNA Diversity between Intracellular and Extracellular Compartments Is Driven by Subgenomic Recombination Events

mBio, 2020
Our understanding of viral defective RNAs (D-RNAs), or truncated viral genomes, comes largely from passaging studies in tissue culture under artificial conditions and/or packaged viral RNAs.
R. M. Langsjoen, Antonio E. Muruato, S. Kunkel, Elizabeth Jaworski, Andrew L. Routh   +4 more
semanticscholar   +1 more source

Comparing Genome Sequencing Methods to Reconstruct the Spread of Piscine Myocarditis Virus in Ireland

Journal of Fish Diseases, Volume 48, Issue 11, November 2025.
ABSTRACT Piscine myocarditis virus (PMCV), a double‐stranded RNA virus, is the causative agent of cardiomyopathy syndrome (CMS) in Atlantic salmon Salmo salar, which was first reported in Ireland in 2012. PMCV continues to be a disease threat to Atlantic salmon aquaculture in Ireland, and as such, it is of growing importance to understand how the virus
Andrew J. Tighe, Jens Carlsson, Neil M. Ruane   +2 more
wiley   +1 more source

Sindbis virus ts103 has a mutation in glycoprotein E2 that leads to defective assembly of virions [PDF]

, 1989
Sindbis virus mutant ts103 is aberrant in the assembly of virus particles. During virus budding, proper nucleocapsid-glycoprotein interactions fail to occur such that particles containing many nucleocapsids are formed, and the final yield of virus is low.
Hahn, Chang S., Lenches, Edith M., Rice, Charles M., Strauss, Ellen G., Strauss, James H.   +4 more
core  

Serum Biomarkers in Atlantic Salmon for Differential Diagnosis of Cardiomyopathy Syndrome and Pancreas Disease: Proteomic Identification of Serum Fibrinogen to Enhance Troponin Immunoassay as Optimal Diagnostic Approach

Journal of Fish Diseases, Volume 48, Issue 11, November 2025.
ABSTRACT Cardiac viral diseases are among the major causes of economic losses in Atlantic salmon (Salmo salar L.) aquaculture. These include cardiomyopathy syndrome (CMS) caused by piscine myocarditis virus (PMCV) and pancreas disease (PD) caused by Atlantic salmonid alphavirus (SAV).
Francesca Riva, Lauren Elaine Black, Kim D. Thompson, Philippe Sourd, Andrei Bordeianu, Christopher C. Chadwick, Hooman Moghadam, Jorge Del‐Pozo, Janina Costa, Richard Burchmore, Nicola Brady, Lewis Moore, Suzanne McGill, Mark McLaughlin, Peter David Eckersall   +14 more
wiley   +1 more source

Advances and Strategies in Enhancing mRNA Cancer Vaccines

Advanced Materials, Volume 37, Issue 42, October 23, 2025.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang, Shengqi Chen, Haijun Hu, Yenhui Ong, Qianqian Ni   +4 more
wiley   +1 more source