Results 141 to 150 of about 27,933 (291)

A Universal Next-Generation Sequencing Protocol To Generate Noninfectious Barcoded cDNA Libraries from High-Containment RNA Viruses

mSystems, 2016
Several biosafety level 3 and/or 4 (BSL-3/4) pathogens are high-consequence, single-stranded RNA viruses, and their genomes, when introduced into permissive cells, are infectious. Moreover, many of these viruses are select agents (SAs), and their genomes
Lindsey A. Moser, Lisbeth Ramirez-Carvajal, Vinita Puri, Steven J. Pauszek, Krystal Matthews, Kari A. Dilley, Clancy Mullan, Jennifer McGraw, Michael Khayat, Karen Beeri, Anthony Yee, Vivien Dugan, Mark T. Heise, Matthew B. Frieman, Luis L. Rodriguez, Kristen A. Bernard, David E. Wentworth, Timothy B. Stockwell, Reed S. Shabman   +18 more
doaj   +1 more source

Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion. [PDF]

, 2016
The host responds to virus infection by activating type I interferon (IFN) signaling leading to expression of IFN-stimulated genes (ISGs). Dysregulation of the IFN response results in inflammatory diseases and chronic infections.
Bozzacco, Leonia, Breton, Gaëlle, Hoffmann, Hans-Heinrich, Li, Melody MH, Loschko, Jakob, MacDonald, Margaret R, Monette, Sébastien, Rice, Charles M, Xiao, Jing W   +8 more
core  

The alphaviruses: gene expression, replication, and evolution [PDF]

, 1994
The alphaviruses are a genus of 26 enveloped viruses that cause disease in humans and domestic animals. Mosquitoes or other hematophagous arthropods serve as vectors for these viruses.
Strauss, Ellen G., Strauss, James H.
core   +1 more source

Agua Salud alphavirus defines a novel lineage of insect-specific alphaviruses discovered in the New World

Journal of General Virology, 2019
The genus Alphavirus harbours mostly insect-transmitted viruses that cause severe disease in humans, livestock and wildlife. Thus far, only three alphaviruses with a host range restricted to insects have been found in mosquitoes from the Old World ...
Kyra Hermanns, M. Marklewitz, Florian Zirkel, Gijs J. Overheul, R. Page, Jose R. Loaiza, C. Drosten, R. V. van Rij, S. Junglen   +8 more
semanticscholar   +1 more source

Advances in Alphavirus and Flavivirus Research

Viruses
Newly emerging viruses, primarily zoonotic or vector-borne, pose a persistent threat to public health and have led to outbreaks of global concern [...]
Kim, YC, Reyes-Sandoval, A
openaire   +4 more sources

Alphavirus infection triggers antiviral RNAi immunity in mammals.

Cell Reports, 2023
Jing Kong, Yuanyuan Bie, Wenting Ji, Jiuyue Xu, Bao Lyu, Xiaobei Xiong, Y. Qiu, Xi Zhou   +7 more
semanticscholar   +1 more source

Alphavirus Replicon Particles as Candidate HIV Vaccines [PDF]

, 2002
Nancy Davis, Ande West, Elizabeth A. Reap, Gene H. MacDonald, Martha Collier, Sergey A. Dryga, Maureen F. Maughan, Mary J. Connell, Chris Walker, Kathryn M. McGrath, Chad Cecil, Li‐Hua Ping, Jeff Frelinger, Robert A. Olmsted, Paula Keith, Ronald Swanstrom, Carolyn Williamson, Philip R. Johnson, David C. Montefiori, Robert E. Johnston   +19 more
openalex   +1 more source

Nonreciprocity in CHIKV and MAYV Vaccine-Elicited Protection

Vaccines
Chikungunya virus (CHIKV) is a pathogenic arthritogenic alphavirus responsible for large-scale human epidemics for which a vaccine was recently approved for use.
Whitney C. Weber, Takeshi F. Andoh, Craig N. Kreklywich, Zachary J. Streblow, Michael Denton, Magdalene M. Streblow, John M. Powers, Gauthami Sulgey, Samuel Medica, Igor Dmitriev, David T. Curiel, Nicole N. Haese, Daniel N. Streblow   +12 more
doaj   +1 more source

The Enigmatic Alphavirus Non-Structural Protein 3 (nsP3) Revealing Its Secrets at Last

Viruses, 2018
Alphaviruses encode 4 non-structural proteins (nsPs), most of which have well-understood functions in capping and membrane association (nsP1), polyprotein processing and RNA helicase activity (nsP2) and as RNA-dependent RNA polymerase (nsP4).
Benjamin Götte, Lifeng Liu, G. McInerney   +2 more
semanticscholar   +1 more source

Nanopore whole genome sequencing and partitioned phylogenetic analysis supports a new salmonid alphavirus genotype (SAV7) [PDF]

, 2020
Andrew J. Tighe, Martin J. Gallagher, Jens Carlsson, Iveta Matějusová, Fiona Swords, DJ Macqueen, Neil M. Ruane   +6 more
openalex   +1 more source