Results 161 to 170 of about 16,243 (206)
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2000
Publisher Summary This chapter describes the mechanics, including how alphaviruses function as expression vectors and some features that make them useful. It also describes some of the ways in which alphaviruses have been used and some potential ways they can be of value. Alphaviruses are positive-strand RNA-enveloped viruses.
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Publisher Summary This chapter describes the mechanics, including how alphaviruses function as expression vectors and some features that make them useful. It also describes some of the ways in which alphaviruses have been used and some potential ways they can be of value. Alphaviruses are positive-strand RNA-enveloped viruses.
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Host responses to alphavirus infection
Immunological Reviews, 2008Summary: Members of the Alphavirus genus are classified into New World and Old World groups based upon their disease characteristics and primary areas of endemicity. The two groups exhibit noteworthy differences in pathogenesis during human infection, with Old World viruses primarily causing febrile and arthritogenic diseases and the New World viruses
Kate D, Ryman, William B, Klimstra
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Alphavirus infections in salmonids – a review
Journal of Fish Diseases, 2007AbstractThe first alphavirus to be isolated from fish was recorded in 1995 with the isolation of salmon pancreas disease virus from Atlantic salmon, Salmo salar L., in Ireland. Subsequently, the closely related sleeping disease virus was isolated from rainbow trout, Oncorhynchus mykiss (Walbaum), in France.
M F, McLoughlin, D A, Graham
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Alphavirus-Based Antigen Preparation
2020Alphavirus-based vectors present an efficient approach for antigen preparation applied for vaccine development. Semliki Forest virus, Sindbis virus, and Venezuelan equine encephalitis virus have been engineered for high-level expression of antigens targeting infectious diseases and tumors.
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Pan-protective anti-alphavirus human antibodies target a conserved E1 protein epitope
Cell, 2021José Quiroz +2 more
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Distinct Cellular Tropism and Immune Responses to Alphavirus Infection
Annual Review of Immunology, 2022Natasha Kafai +2 more
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Therapeutic alphavirus cross-reactive E1 human antibodies inhibit viral egress
Cell, 2021Robert Carnahan +2 more
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Alphavirus-Based Expression Systems
1996Alphaviruses are enveloped positive-strand RNA viruses transmitted to vertebrate hosts via mosquito vectors (reviewed in 34). In the last several years, the alphavirus RNA replication and packaging machinery have been exploited for cytoplasmic expression of heterologous RNAs and proteins in animal cells (for reviews see 3, 24, 27).
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