Results 91 to 100 of about 13,848 (209)

Marked motor function improvement in a 32-year-old woman with childhood-onset hypophosphatasia by asfotase alfa therapy: Evaluation based on standardized testing batteries used in Duchenne muscular dystrophy clinical trials

Molecular Genetics and Metabolism Reports, 2020
Hypophosphatasia (HPP) is a rare disorder resulting from biallelic loss-of-function variants or monoallelic dominant negative variants in the ALPL gene.
Hitomi Nishizawa, Yoshihiko Sato, Masumi Ishikawa, Yuko Arakawa, Mari Iijima, Tomoyuki Akiyama, Kyoko Takano, Atsushi Watanabe, Tomoki Kosho   +8 more
doaj   +1 more source

A quantum measure of coherence and incompatibility

, 2005
The well-known two-slit interference is understood as a special relation between observable (localization at the slits) and state (being on both slits). Relation between an observable and a quantum state is investigated in the general case. It is assumed
Cohen-Tannoudji C, Donald M J, F Herbut, Henderson L, Henneberger W C, Herbut F, Herbut F, Herbut F, Herbut F, Herbut F, Herbut F, Jaeger G, Lindblad G, Lüders G, Messiah A, Ohya M, Schumacher B, Young T, Zurek W H   +18 more
core   +2 more sources

A protective role for FGF-23 in local defence against disrupted arterial wall integrity? [PDF]

, 2013
Increasing interest is focusing on the role of the FGF-23/Klotho axis in mediating vascular calcification. However, the underpinning mechanisms have yet to be fully elucidated. Murine VSMCs were cultured in calcifying medium for a 21d period. FGF-23 mRNA
Ben-Dov, Colin Farquharson, Demer, Ding, Dongxing Zhu, El-Abbadi, Eswarakumar, Franceschi, Hu, Isakova, Johnson, Jose Luis Millan, Khatiwala, Kok, Kurosu, Lim, Liu, Liu, Lorenz-Depiereux, Mackenzie, Mackenzie, Mackenzie, Mackenzie, MacRae, MacRae, MacRae, MacRae, MacRae, Medici, Murshed, Nasrallah, Neil C.W. Mackenzie, Rakugi, Razzaque, Roy, Rutsch, Rutsch, Saito, Salasznyk, Sali, Shalhoub, Shimada, Shimada, Shroff, Simmons, Sitara, Sitara, Speer, Speer, Srivaths, Urakawa, Vicky E. MacRae, Voigt, Wolf, Yamamoto, Yilmaz, Zhu, Zhu   +57 more
core   +1 more source

The skeletal muscle–adipose creatine metabolic axis: A novel paradigm for lipid metabolism reprogramming and obesity management

Experimental Physiology, EarlyView.
Abstract The global prevalence of obesity and related metabolic disorders has spurred interdisciplinary research to develop new intervention strategies. Current research is increasingly focusing on the exercise‐induced browning of white adipose tissue and the mechanisms by which it improves energy metabolism.
Yuhui Su, Na Liu, Yang Liu, Yiqun Sun, Yike Jiao   +4 more
wiley   +1 more source

Effects of Egg Yolk-Derived Peptide on Osteogenic Gene Expression and MAPK Activation

Molecules, 2014
The present study investigated the effects of egg yolk-derived peptide (YPEP) on osteogenic activities and MAPK-regulation of osteogenic gene expressions.
Hye Kyung Kim, Myung-Gyou Kim, Kang-Hyun Leem   +2 more
doaj   +1 more source

Stability Properties of the Time Domain Electric Field Integral Equation Using a Separable Approximation for the Convolution with the Retarded Potential

, 2011
The state of art of time domain integral equation (TDIE) solvers has grown by leaps and bounds over the past decade. During this time, advances have been made in (i) the development of accelerators that can be retrofitted with these solvers and (ii ...
Nair, N. V., Pray, A. J., Shanker, B.
core   +1 more source

Molecular Insights Into Canine Hepatocellular Carcinoma: A Cross‐Species Transcriptomic Comparison With Human HCC

Molecular Carcinogenesis, Volume 65, Issue 4, Page 523-536, April 2026.
ABSTRACT Canine hepatocellular carcinoma (HCC) requires further molecular characterization to identify diagnostic and therapeutic targets, and to establish whether dogs with this condition can model the human disease. Accordingly, we aimed to identify differentially expressed genes (DEGs) in canine HCC and evaluate cross‐species transcriptomic ...
Mohammad Arif, MD Nazmul Hasan, Nobuhiro Nozaki, Yutaro Ide, Yoshiyuki Akiyama, Shaohsu Wang, Most Shumi Akhter Shathi, Osamu Yamato, Naoki Miura   +8 more
wiley   +1 more source

Genome-wide association study on serum alkaline phosphatase levels in a Chinese population [PDF]

, 2013
Background: Serum alkaline phosphatase (ALP) is a complex phenotype influenced by both genetic and environmental factors. Recent Genome-Wide Association Studies (GWAS) have identified several loci affecting ALP levels; however, such studies in Chinese ...
Dai, Xiayun, Deng, Qifei, Deng, Siyun, Guan, Lei, Gui, Lixuan, Guo, Huan, He, Meian, He, Yunfeng, Hu, Die, Hu, Frank B, Huang, Suli, Lang, Mingjian, Li, Dongfeng, Li, Jun, Lin, Dongxin, Min, Xinwen, Wang, Tian, Wu, Chen, Wu, Tangchun, Yang, Binyao, Yang, Handong, Yuan, Jing, Zhou, Li, Zhu, Jiang   +23 more
core   +2 more sources

Expanding Access to Genome Sequencing: Higher Diagnostic Yield in Self‐Referred Participants From the CincyKidsSeq Study and Implications for Hybrid Models of Genetic Service Delivery

Clinical Genetics, Volume 109, Issue 4, Page 717-724, April 2026.
Genome sequencing helped find answers for 1 in 5 children with rare conditions in an outpatient study looking at hybrid genetic care delivery. Families who chose testing themselves had the highest diagnostic yield, showing that self‐referral may be a helpful way to improve access to genetic care.
Kristin Theobald, Amelle Shillington, Farrah Jackson, Jaime Lopes, Casey J. Brewer, Brian Dawson, Gang Wu, James Denton, Mike Pauciulo, Xue Zhang, Anne Slavotinek   +10 more
wiley   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. ABSTRACT Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source