Results 41 to 50 of about 10,706 (212)

Spatial mapping of ectonucleotidase gene expression in the murine urinary bladder

Frontiers in Physiology, 2023
Purinergic signaling is important for normal bladder function, as it is thought to initiate the voiding reflex and modulate smooth muscle tone. The availability of adenine nucleotides and nucleosides (aka purines) at receptor sites of various cell types ...
Mafalda S. L. Aresta Branco, Brian A. Perrino, Violeta N. Mutafova-Yambolieva   +2 more
doaj   +1 more source

A Geometric Variational Approach to Bayesian Inference [PDF]

, 2019
We propose a novel Riemannian geometric framework for variational inference in Bayesian models based on the nonparametric Fisher-Rao metric on the manifold of probability density functions.
Abhijoy Saha, Barber D., Bauer M., Bhattacharyya A, Bishop C. M, Broderick T., Chen T., Ghahramani Z., Hernández-Lobato J., Hoffman M., Hoffman M. D., Jaakkola T., Karthik Bharath, Kass R. E., Kingma D. P., Kucukelbir A., Lang S, Li Y., Minka T. P, Rao C. R, Rezende D., Rényi A, Saul L. K., Sebastian Kurtek, Sigillito V. G., Srivastava A., Tan L. S, Wang C., Yeung D.   +28 more
core   +4 more sources

Effects of Egg Yolk-Derived Peptide on Osteogenic Gene Expression and MAPK Activation

Molecules, 2014
The present study investigated the effects of egg yolk-derived peptide (YPEP) on osteogenic activities and MAPK-regulation of osteogenic gene expressions.
Hye Kyung Kim, Myung-Gyou Kim, Kang-Hyun Leem   +2 more
doaj   +1 more source

Infantile Hypophosphatasia: Clinical Case

Вопросы современной педиатрии, 2020
Background. Hypophosphatasia is rare hereditary disease caused by deficiency of the tissue-nonspecific alkaline phosphatase isozyme. It manifests with bone and teeth mineralisation defects, electrolyte imbalance, respiratory disorders, convulsive ...
Tatyana V. Gabrusskaya, Yana V. Panutina, Maria O. Revnova, Mikhail M. Kostik   +3 more
doaj   +1 more source

7154 Adult Hypophosphatasia With Heterozygous Missense Mutations In ALPL Gene [PDF]

J Endocr Soc
Abstract Disclosure: A.S. Chaugule: None. Y. Cervelo: None. S. Dhillon: None. D. Tuncay: None. We present a case of a male in his third decade of life discovered to be a carrier of the genetic mutation associated with hypophosphatasia during routine pre-conception genetic screening. Genetic analysis revealed a heterozygous
Chaugule, Akshata S, Cervelo, Yeset, Dhillon, Shabnam, Tuncay, Delibasi   +3 more
europepmc   +2 more sources

Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells [PDF]

, 2017
Vascular calcification resulting from hyperphosphatemia is a major determinant of mortality in chronic kidney disease (CKD). Vascular calcification is driven by aldosterone-sensitive osteogenic transformation of vascular smooth muscle cells (VSMCs).
Alesutan, Ioana, Castor, Tatsiana, Feger, Martina, Kratschmar, Denise V., Mia, Sobuj, Sacherer, Michael [u.a.], Voelkl, Jakob   +6 more
core   +1 more source

Generation and characterization of two immortalized human osteoblastic cell lines useful for epigenetic studies [PDF]

, 2017
Different model systems using osteoblastic cell lines have been developed to help understand the process of bone formation. Here, we report the establishment of two human osteoblastic cell lines obtained from primary cultures upon transduction of ...
A Eddleston, AL Boskey, AR Shakoori, C Lipps, C Rentsch, Carolina Sañudo, CI Westacott, CM Cowan, D Benayahu, D Vanderschueren, Flor M. Pérez-Campo, G Jones, H Ishida, H Sudo, H Tullberg-Reinert, J Delgado-Calle, J Delgado-Calle, J Delgado-Calle, J Delgado-Calle, Jana Arozamena, Jeannette Zauers, Jesús Delgado-Calle, JN Beresford, José A. Riancho, JP Leeuwen van, LG Rao, María T. Berciano, MH Mankani, MH Mankani, Miguel Lafarga, MK Sutherland, MM Wong, MP Whyte, N Maruotti, NK Lee, PV Bodine, SA Harris, SA Stewart, SB Rodan, SH Scharla, T Matsumoto, TJ Shaw, TL Chen, Tobias May, U Valentiner, X Li, Y Suzuki   +46 more
core   +2 more sources

Meeting report: a hard look at the state of enamel research. [PDF]

, 2017
The Encouraging Novel Amelogenesis Models and Ex vivo cell Lines (ENAMEL) Development workshop was held on 23 June 2017 at the Bethesda headquarters of the National Institute of Dental and Craniofacial Research (NIDCR).
Bartlett, John D, DenBesten, Pamela, Diekwisch, Thomas Gh, Duverger, Olivier, Joester, Derk, Klein, Ophir D, Kulkarni, Ashok B, Lacruz, Rodrigo S, Millar, Sarah E, Moradian-Oldak, Janet, Pugach, Megan K, Shaw, Wendy, Simmer, James P, Wright, J Timothy   +13 more
core   +1 more source

Perturbation of specific pro-mineralizing signalling pathways in human and murine pseudoxanthoma elasticum [PDF]

, 2014
BACKGROUND: Pseudoxanthoma elasticum (PXE) is characterized by skin (papular lesions), ocular (subretinal neovascularisation) and cardiovascular manifestations (peripheral artery disease), due to mineralization and fragmentation of elastic fibres in the ...
Coucke, Paul, De Paepe, Anne, Hosen, Mohammad Jakir, Le Saux, Olivier, Vanakker, Olivier   +4 more
core   +3 more sources

Genome-wide association study on serum alkaline phosphatase levels in a Chinese population [PDF]

, 2013
Background: Serum alkaline phosphatase (ALP) is a complex phenotype influenced by both genetic and environmental factors. Recent Genome-Wide Association Studies (GWAS) have identified several loci affecting ALP levels; however, such studies in Chinese ...
Dai, Xiayun, Deng, Qifei, Deng, Siyun, Guan, Lei, Gui, Lixuan, Guo, Huan, He, Meian, He, Yunfeng, Hu, Die, Hu, Frank B, Huang, Suli, Lang, Mingjian, Li, Dongfeng, Li, Jun, Lin, Dongxin, Min, Xinwen, Wang, Tian, Wu, Chen, Wu, Tangchun, Yang, Binyao, Yang, Handong, Yuan, Jing, Zhou, Li, Zhu, Jiang   +23 more
core   +2 more sources