Bioactive sphene-based ceramic coatings on cpTi substrates for dental implants: An in vitro study [PDF]
, 2018 Titanium implant surface modifications have been widely investigated to favor the process of osseointegration. The present work aimed to evaluate the effect of sphene (CaTiSiO5) biocoating, on titanium substrates, on the in vitro osteogenic ...
Badocco, Denis +8 more
core +2 more sources
A Geometric Variational Approach to Bayesian Inference [PDF]
, 2019 We propose a novel Riemannian geometric framework for variational inference in Bayesian models based on the nonparametric Fisher-Rao metric on the manifold of probability density functions.
Abhijoy Saha +28 more
core +4 more sources
Phenotypic Profiling in Subjects Heterozygous for 1 of 2 Rare Variants in the Hypophosphatasia Gene (ALPL) [PDF]
Journal of the Endocrine Society, 2020 Abstract Context Hypophosphatasia (HPP) is a syndrome marked by low serum alkaline phosphatase (AlkP) activity as well as musculoskeletal and/or dental disease. While the majority of subjects with HPP carry a pathogenic variant in the ALPL gene or its regulatory regions, individual pathogenic variants
Daniel R Tilden +7 more
openaire +3 more sources
Spatial mapping of ectonucleotidase gene expression in the murine urinary bladder
Frontiers in Physiology, 2023 Purinergic signaling is important for normal bladder function, as it is thought to initiate the voiding reflex and modulate smooth muscle tone. The availability of adenine nucleotides and nucleosides (aka purines) at receptor sites of various cell types ...
Mafalda S. L. Aresta Branco +2 more
doaj +1 more source
Pbx loss in cranial neural crest, unlike in epithelium, results in cleft palate only and a broader midface. [PDF]
, 2018 Orofacial clefting represents the most common craniofacial birth defect. Cleft lip with or without cleft palate (CL/P) is genetically distinct from cleft palate only (CPO).
Berkes +78 more
core +1 more source
Effects of Egg Yolk-Derived Peptide on Osteogenic Gene Expression and MAPK Activation
Molecules, 2014 The present study investigated the effects of egg yolk-derived peptide (YPEP) on osteogenic activities and MAPK-regulation of osteogenic gene expressions.
Hye Kyung Kim +2 more
doaj +1 more source
Zfp462 Is a Key Mediator of Osteoblast Differentiation and Might Contribute to Age-Related Bone Loss. [PDF]
Aging CellOsteoblast‐specific Zfp462 deficiency reduces bone mass and strength, as well as the number of osteocalcin‐positive cells. Zfp462 forms a transcriptional complex with Moz and Runx2 to promote histone H3 acetylation and activate osteogenic gene expression.
Kim JM +11 more
europepmc +2 more sources
Infantile Hypophosphatasia: Clinical Case
Вопросы современной педиатрии, 2020 Background. Hypophosphatasia is rare hereditary disease caused by deficiency of the tissue-nonspecific alkaline phosphatase isozyme. It manifests with bone and teeth mineralisation defects, electrolyte imbalance, respiratory disorders, convulsive ...
Tatyana V. Gabrusskaya +3 more
doaj +1 more source
Primary osteoblast-like cells from patients with end-stage kidney disease reflect gene expression, proliferation, and mineralization characteristics ex vivo. [PDF]
, 2015 Osteocytes regulate bone turnover and mineralization in chronic kidney disease. As osteocytes are derived from osteoblasts, alterations in osteoblast function may regulate osteoblast maturation, osteocytic transition, bone turnover, and skeletal ...
Bowen, Richard E +6 more
core +2 more sources
Meeting report: a hard look at the state of enamel research. [PDF]
, 2017 The Encouraging Novel Amelogenesis Models and Ex vivo cell Lines (ENAMEL) Development workshop was held on 23 June 2017 at the Bethesda headquarters of the National Institute of Dental and Craniofacial Research (NIDCR).
Bartlett, John D +13 more
core +1 more source