Results 41 to 50 of about 2,005 (163)

The future liver remnant in patients undergoing the Associating Liver Partition with Portal Vein Ligation for Staged hepatectomy (ALPPS) maintains the immunological components of a healthy organ.

Frontiers in Medicine, 2016
Background and Aims: A short-interval, two-stage approach termed associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) increases the number of patients with extensive malignant disease of the liver and a small future liver ...
Ram Venkatesh Anantha, Ram Venkatesh Anantha, Christopher Ryan Shaler, Courtney Erin Meilleur, Jeremy Parfitt, S.M. Mansour Haeryfar, S.M. Mansour Haeryfar, Roberto Hernandez-Alejandro   +7 more
doaj   +1 more source

Zeroing Pressures in Urodynamics: Revisiting Current Practice and Pressure Interpretation

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Zeroing of pressure transducers is a fundamental step in urodynamic testing, as it affects pressure tracings and numerical values. Atmospheric zeroing before catheter insertion is the recommended approach, but zeroing with catheters in situ is also used.
Lucas Antonio Pereira do Nascimento, Vicktor Bruno Pereira Pinto, Carlos Henrique Costa, Cristiano M. Gomes   +3 more
wiley   +1 more source

ALPPS: From human to mice highlighting accelerated and novel mechanisms of liver regeneration [PDF]

, 2014
OBJECTIVES: To develop a reproducible animal model mimicking a novel 2-staged hepatectomy (ALPPS: Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy) and explore the underlying mechanisms.
Clavien, Pierre A, Perparim Limani, Andrea Schlegel, Limani, Perparim, Mickael Lesurtel, Emmanuel Melloul, Schlegel, Andrea, Bostjan Humar, Christoph Tschuor, Rolf Graf, Lesurtel, Mickael, Tschuor, Christoph, Pierre A. Clavien, Melloul, Emmanuel, Humar, Bostjan, Graf, Rolf   +15 more
core   +1 more source

Proteomic Profiling Using a Proximity Extension Assay Panel on Serum Samples Stored at −25°C Over Several Decades

PROTEOMICS, Volume 26, Issue 9, Page 106-112, September 2026.
ABSTRACT The advent of proteomics assays that provide accurate levels of thousands of proteins from relatively small sample volumes opens possibilities for biomarker research in biobanks with valuable samples. In this study, we leverage the applicability of the Olink proximity extension assay to profile serum samples of the Janus Serum Bank, which have
Steffan Daniel Bos, Sigrún Helga Lund, Renée Turzanski Fortner, Eivind Hovig, Hilde Langseth   +4 more
wiley   +1 more source

Open Questions in Surgery for Hepatoblastoma: A Joined SIOPEL‐IPSO Survey

European Journal of Haematology, Volume 117, Issue 3, Page 533-542, September 2026.
ABSTRACT Introduction Surgery is pivotal in the management of hepatoblastoma (HB) although approaches and techniques may vary. The Liver Group of the International Society of Pediatric Oncology (SIOPEL) and the International Pediatric Surgical Oncology (IPSO) group collaborated to develop an online survey to investigate specific technical aspects and ...
Chiara Grimaldi, Francesca Gigola, Reto M. Baertschiger, Marco Del Riccio, Hanna Garnier, Gloria Gonzalez, York Tien Lee, Amos Loh, Luca Pio, Sophie Branchereau   +9 more
wiley   +1 more source

Defining benchmark outcomes for ALPPS

, 2019
OBJECTIVE: The aim of this study was to use the concept of benchmarking to establish robust and standardized outcome references after the procedure ALPPS (Associating Liver Partition and Portal Vein Ligation for Staged hepatectomy). BACKGROUND AND AIMS:
Clavien, Pierre-Alain, Hernandez-Alejandro, Roberto, Stavrou, Gregor A, Petrowsky, Henrik, Campos, Ricardo Robles, Fard-Aghaie, Mohammad H, Müller, Philip C, de Santibañes, Eduardo, Raptis, Dimitri A, Hadjittofi, Christopher, Ardiles, Victoria, Linecker, Michael, Oldhafer, Karl J, Machado, Marcel Autran, Malagó, Massimo, Kambakamba, Patryk, Tschuor, Christoph, Tun-Abraham, Mauro   +17 more
core   +1 more source

ALPPS as a salvage procedure after insufficient future liver remnant hypertrophy following portal vein occlusion

, 2017
Background: A minimum future liver remnant (FLR) of 30% is required to avoid post hepatectomy liver failure (PHLF). Portal vein occlusion (PVO) is the main strategy to induce hypertrophy of the FLR, but some patients will not reach sufficient FLR ...
Clavien, Pierre-Alain, Klaus Steinbruck, Eduardo Viana, ALPPS Registry Group, Roberto Hernandez Alejandro, Schadde, Erik, Schadde, Erik,, Robles Campos, Ricardo,, Gayet, Brice, Clavien, Pierre-Alain,, Steinbruck, Klaus, Marcelo Enne, Malago, Massimo,, Gayet, Brice,, Malago, Massimo, Ricardo Robles Campos, Massimo Malago, Hernandez-Alejandro, Roberto, Eduardo De Santibanes, Enne, Marcelo, Hernandez Alejandro, Roberto,, Pierre-Alain Clavien, De Santibanes, Eduardo,, Enne, Marcelo,, Robles Campos, Ricardo, De Santibanes, Eduardo, Bergthór Björnsson, Björnsson, Bergthor,, Björnsson, Bergthór, Steinbruck, Klaus,, Viana, Eduardo, Brice Gayet, Erik Schadde, Viana, Eduardo,   +33 more
core   +1 more source

Conventional Two-Stage Hepatectomy or Associating Liver Partitioning and Portal Vein Ligation for Staged Hepatectomy for Colorectal Liver Metastases? A Systematic Review and Meta-Analysis

Frontiers in Oncology, 2020
Background: Pushing the surgical limits for initially unresectable colorectal liver metastases (CRLM) are two approaches for sequential liver resection: two-stage hepatectomy (TSH) and associating liver partitioning and portal vein ligation for staged ...
Liang Zhang, Liang Zhang, Zhentao Yang, Zhentao Yang, Shiyu Zhang, Shiyu Zhang, Wenchao Wang, Wenchao Wang, Shusen Zheng, Shusen Zheng   +9 more
doaj   +1 more source

ADAMTS4 mediates LPS‐induced cardiac injury and myocardial fibrosis through proteolytic cleavage of TSP1

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
• ADAMTS4 is induced primarily in cardiac fibroblasts during sepsis. • ADAMTS4 cleaves TSP1 at the 236–246 aa functional region. • TSP1 cleavage activates TGF‐β/Smad and NF‐κB signalling in fibroblasts. • Targeting ADAMTS4 reduces fibroblast activation and cardiac fibrosis.
Zhe‐Wei Zhang, Shi‐Yan Wan, Wen Li, Xiao Lu, Rong Chen, Xin Xing, Wei Lai, Shu‐Yang Sheng, M. M. Mosebetsi, Qing‐Tao Meng, Zi‐Long Lu, Di Fan, Wan‐Li Jiang   +12 more
wiley   +1 more source

ALPPS readdresses the management of advanced liver tumors

, 2017
Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) has been developed to induce rapid liver hypertrophy of the future liver remnant (FLR) prior to hepatectomy in primarily non-resectable or marginally resectable liver ...
Jun Kong, Fa-guang Huang, Jian Ping Gong, Jiang-Hua Xiao   +3 more
core   +1 more source