Results 101 to 110 of about 19,041 (222)

A Systematic Review of Adverse Childhood Experiences and Epigenetic Age Acceleration in Later Adult Life Measured With Second and Third‐Generation Epigenetic Clocks

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 4, Page 270-290, June 2026.
ABSTRACT We examined the relationship between adverse childhood experiences (ACEs) and epigenetic age acceleration (EAA) in adulthood as measured by second and third generation epigenetic clocks by performing a systematic review of the literature. The electronic databases MEDLINE and EMBASE were searched on 17 July 2023.
Matthew Green, Laura Horsfall, Azam Saied   +2 more
wiley   +1 more source

Trajectories of genetic risk across dimensions of alcohol use behaviors

Addiction, Volume 121, Issue 5, Page 1153-1165, May 2026.
Abstract Background and aims Alcohol use behaviors (AUBs) manifest in a variety of normative and problematic ways across the life course, all of which are heritable. Twin studies show that genetic influences on AUBs change across development, but this is usually not considered in research identifying and investigating the genes linked to AUBs ...
Jeanne E. Savage, Fazil Aliev, Peter B. Barr, Maia Choi, Gabin Drouard, Megan E. Cooke, Sally I. Kuo, Mallory Stephenson, Sarah J. Brislin, Zoe E. Neale, Spit for Science Working Group, Karen Chartier, Ananda Amstadter, Danielle M. Dick, Emily Lilley, Renolda Gelzinis, Anne Morris, Katie Bountress, Amy E. Adkins, Nathaniel Thomas, Zoe Neale, Kimberly Pedersen, Thomas Bannard, Seung B. Cho, Peter Barr, Holly Byers, Erin C. Berenz, Erin Caraway, James S. Clifford, Megan Cooke, Elizabeth Do, Alexis C. Edwards, Neeru Goyal, Laura M. Hack, Lisa J. Halberstadt, Sage Hawn, Sally Kuo, Emily Lasko, Jennifer Lend, Mackenzie Lind, Elizabeth Long, Alexandra Martelli, Jacquelyn L. Meyers, Kerry Mitchell, Ashlee Moore, Arden Moscati, Aashir Nasim, Jill Opalesky, Cassie Overstreet, A. Christian Pais, Tarah Raldiris, Jessica Salvatore, Jeanne Savage, Rebecca Smith, David Sosnowski, Jinni Su, Chloe Walker, Marcie Walsh, Teresa Willoughby, Madison Woodroof, Jia Yan, Cuie Sun, Brandon Wormley, Brien Riley, Fazil Aliev, Roseann Peterson, Bradley T. Webb, COGA Investigators, Bernice Porjesz, Victor Hesselbrock, Arpana Agrawal, Danielle Dick, Howard J. Edenberg, Tatiana Foroud, Yunlong Liu, Martin H. Plawecki, Samuel Kuperman, Allan Anderson, Jacquelyn Meyers, Laura Bierut, Sarah Hartz, Marc Schuckit, Ronald Hart, Jay Tischfield, Laura Almasy, Alison Goate, Paul Slesinger, Denise Scott, Cathryn Holzhauer, Michie Hesselbrock, Dongbing Lai, John Nurnberger Jr., Leah Wetherill, Xiaoling Xuei, Sean O'Connor, John Kramer, Grace Chan, Chella Kamarajan, Ashwini Pandey, David B. Chorlian, Sivan Kinreich, Gayathri Pandey, Chris Chatzinakos, Jian Zhang, Stacey Saenz deViteri, Christian Richard, Arjun Bingly, Gita Pathak, Andrey Anokhin, Kathleen Bucholz, Fanghong Dong, Alexander Hatoum, Emma Johnson, Vivia McCutcheon, John Rice, Scott Saccone, Zhiping Pang, Sarah Brislin, Jennifer Moore, Alison Merikangas, Miri Gitik, Antti Latvala, Richard J. Rose, Jaakko Kaprio, Danielle M. Dick, Jacquelyn Meyers, Jessica E. Salvatore, Danielle Posthuma   +127 more
wiley   +1 more source

The longitudinal associations of reading, writing and screen time with myopia at age 9 years among children from the GUSTO birth cohort

Acta Ophthalmologica, Volume 104, Issue 3, Page e337-e345, May 2026.
Abstract Purpose To investigate the associations between paper‐based reading and writing time, screen‐based time at ages 2, 3, 6 and 9 years and myopia at age 9 in the GUSTO birth cohort. Methods The GUSTO study recruited pregnant women from two Singapore public maternity hospitals between 2009 and 2010. Parent‐reported reading and writing time, screen
Fan Wu, Chen‐Hsin Sun, Hla Myint Htoon, Jonathan Y. Bernard, Fabian Yap, Yih‐Chung Tham, Charumathi Sabanayagam, Seang‐Mei Saw   +7 more
wiley   +1 more source

Early vascular damage from smoking and alcohol in teenage years: the ALSPAC study [PDF]

European Heart Journal, 2018
To determine the impact of smoking and alcohol exposure during adolescence on arterial stiffness at 17 years.Smoking and alcohol use were assessed by questionnaires at 13, 15, and 17 years in 1266 participants (425 males and 841 females) from the ALSPAC study.
Charakida, Marietta, Georgiopoulos, George, Dangardt, Frida, Chiesa, Scott T, Hughes, Alun D, Rapala, Alicja, Davey Smith, George, Lawlor, Debbie, Finer, Nicholas, Deanfield, John E   +9 more
openaire   +5 more sources

Advances in the genetics of refractive errors: Contributions from the CREAM consortium

Acta Ophthalmologica, Volume 104, Issue 3, Page e222-e231, May 2026.
Abstract The Consortium for Refractive Error and Myopia (CREAM) was established in 2011, bringing together an international team of researchers studying more than 30 cohorts. Since its establishment, CREAM has played a pivotal role in research investigating the genetics of myopia and other refractive errors, serving as a key driver of progress in the ...
Sze Wai Rosa Li, Xi He, Louise Terry, Virginie J. M. Verhoeven, Samantha Sze‐Yee Lee, Gareth Lingham, Jeremy A. Guggenheim, David A. Mackey, Seang‐Mei Saw, Caroline C. W. Klaver, Chi Pui Pang, CREAM Consortium   +11 more
wiley   +1 more source

The impact of pupil behaviour and wellbeing on educational outcomes [PDF]

, 2012
A review of previous literature suggests that wellbeing and learning are associated with one another; however, there is less information on how multiple dimensions of wellbeing together predict later changes in educational outcomes for children and ...
Gutman, Leslie Morrison, Vorhaus, John
core  

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase [PDF]

, 2015
Background Statins are first-line therapy for cardiovascular disease prevention, but their systemic effects across lipoprotein subclasses, fatty acids, and circulating metabolites remain incompletely characterized.
Ala-Korpela, M, Casas, J-P, Chaturvedi, N, Fatemifar, G, Hingorani, AD, Hughes, AD, Jarvelin, M-R, Kahonen, M, Kangas, AJ, Kettunen, J, Kivimaki, M, Lawlor, DA, Lehtimaki, T, Mantyselka, P, Perola, M, Raitakari, OT, Salomaa, V, Sattar, N, Smith, GD, Soininen, P, Tiainen, M, Tillin, T, Tynkkynen, T, Vanhala, M, Wang, Q, Wurtz, P   +25 more
core   +2 more sources

Does early introduction of solid feeding lead to early cessation of breastfeeding?

Maternal and Child Nutrition, 2020
Mixed milk feeding increases the likelihood of breastfeeding cessation, but it is not known if solid feeding (SF) has the same effect. We have identified 10,407 infants breastfed for at least 8–10 weeks from three large U.K.
Angelina Lessa, Ada L. Garcia, Pauline Emmett, Sarah Crozier, Sian Robinson, Keith M. Godfrey, Charlotte M. Wright   +6 more
doaj   +1 more source

Sensory hyperacusis as a predictor of anxiety in adolescence

Journal of Child Psychology and Psychiatry, Volume 67, Issue 5, Page 641-651, May 2026.
Background An increasing number of children report anxiety in early to mid‐adolescence. Early identification of risk during the transition from primary to secondary schools (age 11) could enhance family‐ or school‐based interventions. While known predictors of adolescent anxiety provide some insight, there is a need to identify and understand ...
Foteini Tseliou, Stephan Collishaw, Alice Price, Petroc Sumner   +3 more
wiley   +1 more source

Blood Pressure Variability and Adverse Pregnancy and Cardiovascular Outcomes in the ALSPAC Cohort. [PDF]

J Am Heart Assoc
Background Outside pregnancy, blood pressure variability (BPV) predicts cardiovascular events. We aimed to study associations (if any) between visit‐to‐visit BPV in pregnancy and (1) adverse maternal/perinatal outcomes, and (2) long‐term maternal cardiovascular outcomes. We conducted a secondary analysis of data
Wilson M, Elanko A, Mistry H, Bone J, Slade L, Singer J, McManus R, von Dadelszen P, Magee LA.   +8 more
europepmc   +3 more sources