Results 11 to 20 of about 21,134 (240)

Inflammation proteomics datasets in the ALSPAC cohort

Wellcome Open Research, 2022
Proteomics is the identification, detection and quantification of proteins within a biological sample. The complete set of proteins expressed by an organism is known as the proteome. The availability of new high-throughput proteomic technologies, such as
Neil J Goulding, L. Goudswaard, D. Hughes, L. Corbin, A. Groom, S. Ring, N. Timpson, A. Fraser, K. Northstone, M. Suderman   +9 more
semanticscholar   +5 more sources

Cohort profile: the avon longitudinal study of parents and children: ALSPAC mothers cohort [PDF]

International Journal of Epidemiology, 2013
The Avon Longitudinal Study of Children and Parents (ALSPAC) was established to understand how genetic and environmental characteristics influence health and development in parents and children.
A. Boyd, A. Fraser, A. Ness, Alati, C. Macdonald-Wallis, Chen, Chittleborough, Cookson, D. A. Lawlor, Davey Smith, Deave, Dudding, Evans, FARROW, Fergusson, G. Davey Smith, Golding, Golding, Golombok, Hibbeln, J. Golding, J. Henderson, J. Macleod, Jeffreys, K. Tilling, L. Molloy, Lawlor, Lawlor, Leary, Lewis, Liu, Loos, Macdonald-Wallis, Macdonald-Wallis, Macdonald-Wallis, Macleod, Micali, Northstone, O'Connor, O'CONNOR, O'Connor, O'Connor, Perry, Rogers, S. M. Nelson, S. Ring, Shugart, Smith, Weedon, Willer, Zammit   +50 more
core   +3 more sources

Cognitive functioning in anxiety and depression: results from the ALSPAC cohort [PDF]

Royal Society Open Science, 2021
Anxiety and depression are associated with a range of impairments in cognitive functioning. Understanding the nature of these deficits may identify targets for intervention and prevent functional decline.
S. Suddell, L. Mahedy, C. Skirrow, I. Penton-Voak, M. Munafo, R. Wootton   +5 more
semanticscholar   +5 more sources

ALSPAC parents’ descriptions of childhood stresses in their parents and grandparents [PDF]

Wellcome Open Research, 2021
Background: There is evidence that childhood stresses or traumas influence individuals’ descendants’ health and wellbeing through epigenetic mechanisms. However, few longitudinal studies have details of such ancestral data.
K. Birmingham, Y. Iles-Caven, J. Golding
semanticscholar   +5 more sources

Enhancing Environmental data Resources in Cohort Studies: ALSPAC exemplar (ERICA)

International Journal of Population Data Science, 2018
Introduction Novel data platforms are needed to expedite the linkage of geospatial and natural environment data with longitudinal population study(ies) (LPS) data.
Andy Boyd
doaj   +4 more sources

The Avon Longitudinal Study of Parents and Children (ALSPAC): a 2022 update on the enrolled sample of mothers and the associated baseline data [version 2; peer review: 2 approved]

Wellcome Open Research, 2023
The Avon Longitudinal Study of Parents and Children (ALSPAC) is a prospective birth cohort, based in and around Bristol, UK, established to explore genetic and environmental factors impacting health and development.
Kate Northstone, Jean Golding, Jon Heron, Abigail Fraser, Daniel Major-Smith, Deborah A. Lawlor   +5 more
doaj   +2 more sources

Maternal reports of morbidity during the index ALSPAC pregnancy [version 2; peer review: 2 approved] [PDF]

Wellcome Open Research, 2022
Within the ALSPAC (Avon Longitudinal Study of Parents and Children) resource, information concerning the health of the mother during pregnancy is available from three sources: (i) computerised data collected by midwives after the birth of the baby, known
Kate Northstone, Jean Golding, Yasmin Iles-Caven, Abigail Fraser, Genette Ellis   +4 more
doaj   +4 more sources

Releasing synthetic data from the Avon Longitudinal Study of Parents and Children (ALSPAC): Guidelines and applied examples [version 2; peer review: 1 approved, 2 approved with reservations]

Wellcome Open Research
The Avon Longitudinal Study of Parents and Children (ALSPAC) is a prospective birth cohort. Since its inception in the early 1990s, the study has collected over thirty years of data on approximately 15,000 mothers, their partners, and their offspring ...
Nicholas J. Timpson, Kate Northstone, Jon Heron, Daniel Major-Smith, Alex S. F. Kwong   +4 more
doaj   +2 more sources

The second generation of The Avon Longitudinal Study of Parents and Children (ALSPAC-G2): a cohort profile [version 2; peer review: 2 approved]

Wellcome Open Research, 2019
Background: The Avon Longitudinal Study of Parents and Children-Generation 2 (ALSPAC-G2) was set up to provide a unique multi-generational cohort. It builds on the existing ALSPAC resource, which recruited 14,541 pregnancies to women resident in the ...
Deborah A. Lawlor, Melanie Lewcock, Louise Rena-Jones, Claire Rollings, Vikki Yip, Daniel Smith, Rebecca M. Pearson, Laura Johnson, Louise A. C. Millard, Nashita Patel, Andy Skinner, Kate Tilling, ALSPAC Executive   +12 more
doaj   +2 more sources

Ascertaining and classifying cases of congenital anomalies in the ALSPAC birth cohort [PDF]

Wellcome Open Research, 2021
Congenital anomalies (CAs) are structural or functional disorders that occur during intrauterine life. Longitudinal cohort studies provide unique opportunities to investigate potential causes and consequences of these disorders.
K. Taylor, Richard Thomas, Mark Mummé, J. Golding, A. Boyd, K. Northstone, Massimo Caputo, Deborah A. Lawlor   +7 more
semanticscholar   +3 more sources