Results 71 to 80 of about 703,394 (261)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Overcoming Hole‐Extraction Barriers: A Facile PEDOT:PSS Interlayer Unlocks Record‐Low Voltage Deficit in PbS Quantum Dot Solar Cells

open access: yesAdvanced Science
The development of colloidal quantum dot solar cells (CQDSCs) is currently constrained by the substantial open‐circuit voltage (Voc) deficit and intricate fabrication processes.
Shengkai Kang   +11 more
doaj   +1 more source

Utilization of Biomass to Ash: An Overview of the Potential Resources for Alternative Energy. [PDF]

open access: yesMaterials (Basel), 2021
Makul N   +9 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

First-principles computation of dislocation structures and stress-driven phase transformations in layered oxides for Na-ion batteries

open access: yesnpj Computational Materials
Dislocation dynamics at the atomic scale play a significant role in phase transformations and mechanical degradation of layered cathode materials in Na-ion batteries (NIBs), yet their fundamental behavior remains poorly understood.
Oier Arcelus, Javier Carrasco
doaj   +1 more source

Home - About - Disclaimer - Privacy