Results 121 to 130 of about 786,469 (327)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Astronomy in Chile: Assessment of scientific productivity through a bibliometric analysis

open access: yesEPJ Web of Conferences, 2018
The skies of Northern Chile are considered among the best in the world for astronomy due to their geographical, climatic and atmospheric conditions. In fact, during the last several decades, a great number of astronomical observatories have been built by
Cortes Rodrigo   +2 more
doaj   +1 more source

Recent trends in the use of social media in parasitology and the application of alternative metrics. [PDF]

open access: yesCurr Res Parasitol Vector Borne Dis, 2021
Ellis J, Ellis B, Tyler K, Reichel MP.
europepmc   +1 more source

Warped Electroweak Breaking Without Custodial Symmetry

open access: yes, 2010
We propose an alternative to the introduction of an extra gauge (custodial) symmetry to suppress the contribution of KK modes to the T parameter in warped theories of electroweak breaking.
Agashe   +34 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Introduction to Altmetrics: A new metric for evaluating the impact of scientific outputs and collaborations

open access: yesمجله علم‌سنجی کاسپین, 2015
Background and aim: Altmetrics seeks to assess the scientific impact with new ways using data derived from the social Web. The aim of this paper aims to represent the concept, benefits, disadvantages and challenges of Altmetrics.
farahnaz naderbeygi   +2 more
doaj  

Sensitivity analysis of the scor metrics selected for the measurement of the management of a fruit-growing supply chain

open access: yesDyna, 2017
This paper presents the sensitivity analysis performed on metrics of the SCOR model in order to measure the management of a fruit-growing supply chain of small producers.
Diego Leon Peña-Orozco, Leonardo Rivera
doaj   +1 more source

Alternatives to standard puncture initial data for binary black hole evolution

open access: yes, 2012
Standard puncture initial data have been widely used for numerical binary black hole evolutions despite their shortcomings, most notably the inherent lack of gravitational radiation at the initial time that is later followed by a burst of spurious ...
G. B. Cook   +4 more
core   +1 more source

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