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Science, 2004
IMMUNOLOGY Cell-surface receptors in the signaling lymphocyte activation molecule (SLAM) family play diverse roles in the lives of T and B lymphocytes, NK cells, dendritic cells, and macrophages.
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IMMUNOLOGY Cell-surface receptors in the signaling lymphocyte activation molecule (SLAM) family play diverse roles in the lives of T and B lymphocytes, NK cells, dendritic cells, and macrophages.
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The Complement Alternative Pathway and Preeclampsia
Current Hypertension Reports, 2018Significant and intricate immune adaptations are essential for the establishment and maintenance of normal pregnancy. Preeclampsia is a morbid, potentially life-threatening disease for both mother and neonate that occurs uniquely in pregnancy, at least in part, due to maternal immune maladaptation.
Layan Alrahmani, Maria Alice V. Willrich
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Alternating Views on the ABR Alternate Pathway
RadiologyThe alternate pathway to American Board of Radiology certification has recently gained traction among international graduates; drawing from personal experiences, we summarize the challenges candidates may face, hoping to prepare potential candidates for the hurdles ahead.
Adarsh Ghosh, Eric Crotty
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The Alternative Pathway of Complement Activation
1976Publisher Summary This chapter presents the alternative pathway of complement activation. Two pathways for the recruitment of complement and its biological activities exist in plasma and serum. The first is termed as the “classical pathway,” which is triggered by contact of C1 with immune complexes containing antibodies of the immunoglobulin G (IgG ...
Otto Götze, Hans J. Müller-Eberhard
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Alternative Pathways to Certification
2019This chapter explores the literature on alternative pathways to teacher certification to provide a context for understanding how and why these programs developed and their potential impact on traditional pathways to licensure. A discussion of the different types of alternative certification programs, including graduate-level teacher certification ...
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2007
There are four members of the mammalian p38 mitogen-activated protein kinases (MAPKs) family (p38α, p38β, p38γ, and p38δ) which are about 60% identical in their amino acid sequence but differ in their expression patterns, substrate specificities, and sensitivities to chemical inhibitors such as SB203580.
Ana Cuenda +3 more
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There are four members of the mammalian p38 mitogen-activated protein kinases (MAPKs) family (p38α, p38β, p38γ, and p38δ) which are about 60% identical in their amino acid sequence but differ in their expression patterns, substrate specificities, and sensitivities to chemical inhibitors such as SB203580.
Ana Cuenda +3 more
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Alternative protein sorting pathways
2000The term "nonclassical protein targeting" has been used to describe those pathways that have been recently discovered and differ mechanistically from the more studied "classical pathways." Because this nomenclature is rather arbitrary in terms of cellular relevance, we have chosen to group these protein sorting mechanisms under the heading "alternative
Sidney V. Scott +2 more
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Science, 2011
Biochemistry The low-molecular-weight thiol glutathione (GSH) is essential for growth in eukaryotes and plays a central role in stress responses and the maintenance of redox homeostasis in certain bacteria. Surprisingly, most aerobic bacteria lack the GSH biosynthesis enzyme glutamate cysteine ligase (GshA), although many have genes encoding proteins ...
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Biochemistry The low-molecular-weight thiol glutathione (GSH) is essential for growth in eukaryotes and plays a central role in stress responses and the maintenance of redox homeostasis in certain bacteria. Surprisingly, most aerobic bacteria lack the GSH biosynthesis enzyme glutamate cysteine ligase (GshA), although many have genes encoding proteins ...
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Alternate interferon signaling pathways
Pharmacology & Therapeutics, 2003More than a half a century ago, interferons (IFN) were identified as antiviral cytokines. Since that discovery, IFN have been in the forefront of basic and clinical cytokine research. The pleiotropic nature of these cytokines continues to engage a large number of investigators to define their actions further.
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[47] Carotenoid cleavage: Alternative pathways
1990Publisher Summary The best evidence for excentric cleavage of carotenoids is the demonstration of the presence of 8’-, 10’-, and 12’-β-apocarotenals in small intestinal tissue taken from animals previously consuming carotenoids. Other evidence is provided by observations of the oxidative fission of carotenoids in model systems devoid of cells or ...
L.E. Gerber, K.L. Simpson
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