Source leaves are regulated by sink strengths through non-coding RNAs and alternative polyadenylation in cucumber (Cucumis sativus L.). [PDF]
Wang Y+5 more
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Alternative Polyadenylation Characterizes Epithelial and Fibroblast Phenotypic Heterogeneity in Pancreatic Ductal Adenocarcinoma. [PDF]
Venkat S, Feigin ME.
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RBBP6 maintains glioblastoma stem cells through CPSF3-dependent alternative polyadenylation. [PDF]
Lin P+16 more
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Nudt21-mediated alternative polyadenylation of MZT1 3'UTR contributes to pancreatic cancer progression. [PDF]
Zhou Y+6 more
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Colocalization analysis of 3' UTR alternative polyadenylation quantitative trait loci reveals novel mechanisms underlying associations with lung function. [PDF]
Saferali A+7 more
europepmc +1 more source
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Alternative polyadenylation regulation: insights from sequential polyadenylation
Transcription, 2022The processing of the proximal and distal poly(A) sites in alternative polyadenylation (APA) has long been thought to independently occur on pre-mRNAs during transcription. However, a recent study by our groups demonstrated that the proximal sites for many genes could be activated sequentially following the distal ones, suggesting a multi-cleavage-same-
Peng Tang, Yu Zhou
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Alternative polyadenylation and the stress response
WIREs RNA, 2019AbstractThe cellular stress response is a universal mechanism necessary for the survival of all organisms. This multifaceted process is primarily driven by regulation of gene expression to produce an intracellular environment suitable for promoting cell survival and recovery.
Jason Sadek+4 more
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