Results 91 to 100 of about 2,296,262 (307)

The novel MAPT mutation K298E:mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons [PDF]

, 2013
Frontotemporal lobar degeneration (FTLD) consists of a group of neurodegenerative diseases characterized by behavioural and executive impairment, language disorders and motor dysfunction.
Calo, Laura, Goedert, Michel, Holton, Janice L., Iovino, Mariangela, Lashley, Tammaryn, Lund University., Lund University., Lund University., Muqit, Miratul M. K., Parmar, Malin,, Pfisterer, Ulrich,, Revesz, Tamas, Spillantini, Maria Grazia, Swingler, Robert J., Treacy, Rebecca   +14 more
core   +4 more sources

Nordic Alternative Protein Potentials

, 2016
Within agri- and aquaculture, a specific bioeconomy challenge – and a bioeconomy opportunity – has been identified concerning sustainable protein supply for livestock production and fish farming.
Jan Erik Lindberg, Gunnar Lindberg, Jukka Teräs, Gert Poulsen, Svein Øivind Solberg, Knud Tybirk, Joanna Przedrzymirska, Grazyna Pazikowska Sapota, Malene Lihme Olsen, Hilary Karlson, Ragnar Jóhannsson, Birgir Örn Smárason, Morten Gylling, Marie Knudsen   +13 more
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Applications of solid-state fermented (SSF) diets to improve the growth, organ health, immunity and disease resistance through modulating the transcriptomics and proteomics profile in fish and shrimp

AIMS Microbiology
Fish meal (FM) has long been used as a staple protein source in aquafeed owing to its balanced amino acids, excellent feed conversion, and improved palatability and digestibility.
Shishir Kumar Nandi, Sanchita Sarkar, Md. Toasin Hossain Aunkor, Zulhisyam Abdul Kari, Tanwi Dey, Hien Van Doan, El-Sayed Hemdan Eissa, Mohamad Nor Azra, Muhammad A.B. Siddik, Muhammad Anamul Kabir   +9 more
doaj   +1 more source

Suppression of ILC2 differentiation from committed T cell precursors by E protein transcription factors [PDF]

, 2019
Current models propose that group 2 innate lymphoid cells (ILC2s) are generated in the bone marrow. Here, we demonstrate that subsets of these cells can differentiate from multipotent progenitors and committed T cell precursors in the thymus, both in ...
Adrianto, Indra, Alberola-Ila, Jose, Bajana, Sandra, Colonna, Marco, Georgescu, Constantin, Peng, Vincent, Qian, Liangyue, Sun, Xiao-Hong, Wang, Hong-Cheng, Wren, Jonathan D   +9 more
core   +1 more source

Effect of Lupinus albus as protein supplement on yield, constituents, clotting properties and fatty acid composition in ewes' milk [PDF]

, 2006
The effect of feeding lupin seeds (Lupinus albus L.) as an alternative protein source in ewe diets was investigated. Two groups of 18 Sarda ewes were fed two different isonitrogenous diets: with lupin (L) seed, given after 12 h soaking, or soybean meal ...
DI FRANCIA, ANTONIO, LAMBIASE, GIANFRANCO, M. T. MARESCA DI SERRACAPRIOLA, MASUCCI, FELICIA, PROTO, VINCENZO, ROMANO, RAFFAELE, VARRICCHIO, MARIA LUISA   +6 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Future Directions for Sustainable Poultry Feeding and Product Quality: Alternatives from Insects, Algae and Agro-Industrial Fermented By-Products

Agriculture
Due to global increases in poultry meat and egg production, consumers request sustainable agricultural practices, requiring alternative solutions for future feeding. Global egg production increased by over 41% between 2000 and 2020, from 51 to 87 million
Petru Alexandru Vlaicu, Raluca Paula Turcu, Mihaela Dumitru, Arabela Elena Untea, Alexandra Gabriela Oancea   +4 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Exploring the Bacterial Microbiome of High-Moisture Plant-Based Meat Substituted Soybean Flour with Mung Bean Protein and Duckweed Powder

Biology
(1) Background: This study aimed to investigate the bacterial microbiomes in the ingredients and final PBM products during a storage period of 28 days at 2–4 °C for food safety and quality. (2) Methods: DNA from raw ingredients (i.e., defatted soy flour,
Jutamat Klinsoda, Theera Thurakit, Kullanart Tongkhao, Khemmapas Treesuwan, Kanokwan Yodin, Hataichanok Kantrong   +5 more
doaj   +1 more source