Results 121 to 130 of about 2,296,262 (307)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Sustainable Valorisation of Coffee Waste as a Protein Source, Mycelium-Based Packaging Material and Renewable Energy Pellet

Molecules
This study investigates the valorization of spent coffee grounds (SCGs) through protein extraction and their application in mycelium-based packaging and renewable energy pellets.
Anca Becze, Dorina Simedru, Daniel-Gabriel Barta, Lacrimioara Senila, Cerasel Varaticeanu, Tudor Blaga   +5 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Optimization-Based Peptide Mass Fingerprinting for Protein Mixture Identification [PDF]

, 2008
*Motivation:* In current proteome research, peptide sequencing is probably the most widely used method for protein mixture identification. However, this peptide-centric method has its own disadvantages such as the immense volume of tandem Mass ...
Can Yang, Chao Yang, Jason Po-Ming Tam, Robert Z Qi, Weichuan Yu, Zengyou He   +5 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Key Manufacturing Technologies of Microbial Protein and Its Application in Food Industry

中国工程科学
Food protein is one of the most important nutrients for human beings. The existing ways of obtaining protein are difficult to satisfy the huge demand for protein supply owing to the continuous growth of population and the continuous improvement in living
Wang Chao , Xia Lu , Li Zhaofeng , Chen Jian   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Inclusion of mussel meal in diets to growing/finishing pigs [PDF]

, 2013
This study showed that inclusion of mussel meal in diets to growing/finishing pigs yielded growth rate similar to those obtained with a conventional diet, whereas feed conversion ratio was higher.
Andersson, K., Lundeheim, N., Wallenbeck, A.   +2 more
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Comprehensive Review of Alternative Proteins in Pet Food: Research Publications, Patents, and Product Trends in Plant, Aquatic, Insect, and Cell-Based Sources

Foods
The increasing demand for sustainable pet-food solutions has driven interest in alternative protein sources, as researchers seek to avoid allergenic foods while maintaining optimal pet nutrition.
Phatthranit Klinmalai, Pitiya Kamonpatana, Arisara Thongpech, Janenutch Sodsai, Khwanchat Promhuad, Atcharawan Srisa, Yeyen Laorenza, Attawit Kovitvadhi, Sathita Areerat, Anusorn Seubsai, Shyam S. Sablani, Nathdanai Harnkarnsujarit   +11 more
doaj   +1 more source