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Toxin Neutralization Using Alternative Binding Proteins [PDF]
Animal toxins present a major threat to human health worldwide, predominantly through snakebite envenomings, which are responsible for over 100,000 deaths each year. To date, the only available treatment against snakebite envenoming is plasma-derived antivenom.
Jenkins, Timothy Patrick +6 more
openaire +6 more sources
Livestock Farmers’ Attitudes towards Alternative Proteins
New food technologies such as cultured meat, precision fermentation, and plant-based alternatives may one day supplant traditional modes of animal farming. Nonetheless, very little is known about how traditional animal farmers perceive these new products, despite being directly impacted by their advance.
Chloe Crawshaw, Jared Piazza
openaire +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Several alternative proteins have emerged that may improve the environmental footprint of our food system. Evaluations into the impact of these protein sources on gastrointestinal health is limited.
Massimo Marzorati +4 more
doaj +1 more source
Alternative Protein-Protein Interfaces Are Frequent Exceptions
The intricate molecular details of protein-protein interactions (PPIs) are crucial for function. Therefore, measuring the same interacting protein pair again, we expect the same result. This work measured the similarity in the molecular details of interaction for the same and for homologous protein pairs between different experiments.
Tobias Hamp, Burkhard Rost
openaire +4 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Oleosomes are spherical subcellular organelles comprising triacylglycerols and sterol esters (lipid core) surrounded by a specialized monolayer membrane, composed of proteins, phospholipids, and phytochemicals (e.g., isoflavones, phytosterols, and ...
Zafarullah Muhammad +7 more
doaj +1 more source
Protein–protein alternative binding modes do not overlap [PDF]
AbstractProteins often bind other proteins in more than one way. Thus alternative binding modes is an essential feature of protein interactions. Such binding modes may be detected by X‐ray crystallography and thus reflected in Protein Data Bank. The alternative binding is often observed not for the protein itself but for its structural homolog.
Petras J, Kundrotas, Ilya A, Vakser
openaire +2 more sources
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Scale-Up of Alfalfa (Medicago sativa) Protein Recovery Using Screw Presses
As a consequence of the increased demand for proteins for both feed and food, alternative protein sources from green plants such as alfalfa (Medicago sativa) have come into focus, together with methods to recover these proteins.
Mikkel Hansen +3 more
doaj +1 more source

