Coarse-grained model of entropic allostery [PDF]
, 2004 Many signaling functions in molecular biology require proteins to bind to substrates such as DNA in response to environmental signals such as the simultaneous binding to a small molecule. Examples are repressor proteins which may transmit information via
A. Cooper +13 more
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Muscleblind proteins regulate alternative splicing [PDF]
The EMBO Journal, 2004 Although the muscleblind (MBNL) protein family has been implicated in myotonic dystrophy (DM), a specific function for these proteins has not been reported. A key feature of the RNA-mediated pathogenesis model for DM is the disrupted splicing of specific pre-mRNA targets.
Thai H, Ho +5 more
openaire +2 more sources
Arginyltransferase, Its Specificity, Putative Substrates, Bidirectional Promoter, and Splicing-derived Isoforms [PDF]
, 2006 Substrates of the N-end rule pathway include proteins with destabilizing N-terminal residues. Three of them, Asp, Glu, and (oxidized) Cys, function through their conjugation to Arg, one of destabilizing N-terminal residues that are recognized directly by
Brower, Christopher S. +7 more
core +2 more sources
Insects, 2022 The expected global population growth to 9.7 billion people in 2050 and the significant change in global dietary patterns require an increase in global food production by about 60%.
Teun Veldkamp +9 more
doaj +1 more source
Exploiting Homology Information in Nontemplate Based Prediction of Protein Structures [PDF]
, 2015 In this paper we describe a novel strategy for exploring the conformational space of proteins and show that this leads to better models for proteins the structure of which is not amenable to template based methods. Our strategy is based on the assumption
Alfredo Iacoangeli +3 more
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Conformational analysis of alternative protein structures [PDF]
Bioinformatics, 2007 AbstractMotivation: Alternative structural models determined experimentally are available for an increasing number of proteins. Structural and functional studies of these proteins need to take these models into consideration as they can present considerable structural differences.
Domingues, F. +2 more
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Large-scale identification and characterization of alternative splicing variants of human gene transcripts using 56 419 completely sequenced and manually annotated full-length cDNAs [PDF]
, 2006 We report the first genome-wide identification and characterization of alternative splicing in human gene transcripts based on analysis of the full-length cDNAs.
Jun-ichi Takeda +65 more
core +2 more sources
Sorghum as a Potential Valuable Aquafeed Ingredient: Nutritional Quality and Digestibility
Agriculture, 2022 The world population is increasing, and our current agricultural practices are not sustainable enough to address the concerns. Alternative proteins including plant-based proteins would provide a more sustainable source of food and feed ingredients. Among
Mohammad Zarei +5 more
doaj +1 more source
The role of bushmeat in urban household consumption: Insights from Bangui, the capital city of the Central African Republic [PDF]
, 2017 In the Congo Forest Basin, hunting provides a major source of protein for rural household consumption. In the context of increasing urbanisation, an understanding of bushmeat consumption in urban settings is needed to both address food security issues ...
Drouet-Hoguet, Nolwenn +2 more
core +1 more source
Phage display selected magnetite interacting Adhirons for shape controlled nanoparticle synthesis [PDF]
, 2015 Adhirons are robust, well expressing, peptide display scaffold proteins, developed as an effective alternative to traditional antibody binding proteins for highly specific molecular recognition applications.
Bramble, Jonathan P. +8 more
core +2 more sources