Results 41 to 50 of about 1,685,857 (295)

In planta localisation patterns of MADS domain proteins during floral development in Arabidopsis thaliana [PDF]

, 2009
Background: MADS domain transcription factors play important roles in various developmental processes in flowering plants. Members of this family play a prominent role in the transition to flowering and the specification of floral organ identity. Several
Angenent, G.C., Folter, S., de, Immink, G.H., Kaufmann, K., Shchennikova, A., Urbanus, S.L.   +5 more
core   +3 more sources

An Alternative Approach to Protein Folding [PDF]

BioMed Research International, 2013
A diffusion theory-based, all-physicalab initioprotein folding simulation is described and applied. The model is based upon the drift and diffusion of protein substructures relative to one another in the multiple energy fields present. Without templates or statistical inputs, the simulations were run at physiologic and ambient temperatures (including ...
Kang, Yeona, Fortmann, Charles M.
openaire   +2 more sources

BLUF Domain Function Does Not Require a Metastable Radical Intermediate State [PDF]

, 2014
BLUF (blue light using flavin) domain proteins are an important family of blue light-sensing proteins which control a wide variety of functions in cells. The primary light-activated step in the BLUF domain is not yet established. A number of experimental
Agnieszka Gil, Allison Haigney, Anderson S., Andras Lukacs, Bonetti C., Bonetti C., Braatsch S., Brust R., Brust R., Domratcheva T., Dragnea V., Duvanel G., Fiedler B., Gauden M., Gauden M., Gauden M., Gomelsky M., Greetham G. M., Gregory M. Greetham, Grinstead J. S., Haigney A., Haigney A., Hsiao Y.-W., Ishikita H., Jung A., Kennis J. T. M., Khrenova M. G., Khrenova M. G., Kiri Addison, Kondo M., Kottke T., Laan W., Laan W., Losi A., Losi A., Lukacs A., Lukacs A., Lukacs A., Marcus R. A., Masuda S., Masuda S., Masuda S., Masuda S., Masuda S., Mathes T., Mathes T., Mathes T., Meier K., Meier K., Michael Towrie, Moglich A., Mussi M. A., Okajima K., Peter J. Tonge, Pimenta F. M., Reece S. Y., Reece S. Y., Richard Brust, Rosspeintner A., Rosspeintner A., Ruiz-Gonzalez R., Sadeghian K., Sadeghian K., Sadeghian K., Sato Y., Sergey P. Laptenok, Seyedsayamdost M. R., Stelling A. L., Stephen R. Meech, Stierl M., Tommos C., Udvarhelyi A., Udvarhelyi A., Unno M., Unno M., Van der Horst M. A., Walden S. E., Wolf M. M. N., Zhao R.-K.   +78 more
core   +2 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Probing protein sequences as sources for encrypted antimicrobial peptides [PDF]

, 2012
Starting from the premise that a wealth of potentially biologically active peptides may lurk within proteins, we describe here a methodology to identify putative antimicrobial peptides encrypted in protein sequences.
Alan Cooper, Carlos Bloch, Eugene A. Permyakov, Francisco J. L. Aragão, Guilherme D. Brand, Jacques Nicoli, Maria L. P. Tinoco, Mariana T. Q. Magalhães, Sharon M. Kelly   +8 more
core   +12 more sources

Egg Quality and Laying Performance of Rhode Island Red Hens Fed with Black Soldier Fly Larvae and Microalgae Meal as an Alternative Diet

Animals
The potential of black soldier fly larvae (BSFL) and microalgae (MA) in poultry diets has garnered increasing interest due to their high nutritional value and reduced environmental footprint.
Marta Montserrat Tovar-Ramírez, Mónica Vanessa Oviedo-Olvera, Maria Isabel Nieto-Ramirez, Benito Parra-Pacheco, Ana Angelica Feregrino-Pérez, Juan Fernando Garcia-Trejo   +5 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Alternative Proteins

This is the author accepted manuscript. ; ‘Alternative proteins’ is a term used describe a diverse set of foodstuffs that have been posited as potential replacements in an individual’s diet for livestock products such as meat, milk and egg. Core examples include foods in which the core ingredients are insects, plant-based replications of meat, or novel
Elif Feyza Aydar, Zehra Mertdinç, Evren Demircan, Aslı Can Karaca, Kadriye Nur Kasapoğlu, Beraat Özçelik   +5 more
openaire   +2 more sources

Negative feedback control of jasmonate signaling by an alternative splice variant of JAZ10 [PDF]

, 2013
The plant hormone jasmonate (JA) activates gene expression by promoting ubiquitin-dependent degradation of JAZ transcriptional repressor proteins. A key feature of all JAZ proteins is the highly conserved Jas motif, which mediates both JAZ degradation ...
Campos, Marcelo L., Chung, Hoo Sun, He, Sheng Hang, Howe, Gregg A., Moreno, Javier Edgardo, Patel, Lalita C., Shyu, Christine, Yao, Jian   +7 more
core   +1 more source