Results 61 to 70 of about 3,070,354 (249)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Maintenance efficient routing in wireless sensor networks [PDF]

open access: yes, 2005
Communication patterns define the energy depletion profile of a wireless sensor network. In particular, routing defines which areas of the sensor field are subject to a higher traffic load. In these areas, sensor nodes deplete faster than in areas with a
C. Sreenan   +5 more
core   +2 more sources

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Performance Evaluation of Routing Metrics in the LOADng Routing Protocol

open access: yesJournal of Communications Software and Systems, 2017
LOADng (Lightweight On-demand Ad hoc Distance-vector Routing Protocol - Next Generation) is an emerging routing protocol that emerged as an alternative to RPL (IPv6 Routing Protocol for Low power and Lossy Networks). Although some work has been dedicated
Jose V. V. Sobral   +4 more
doaj  

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

2003 Workshop on High Performance Switching and Routing (HPSR 2003)

open access: yes, 2003
Shortest path routing schemes, like open shortest path first (OSPF), have shortcomings when networks are highly loaded. Traffic engineering of IP networks is required to avoid this problem.
Harris, Richard J., Kist, Alexander A.
core   +1 more source

Routing through open spaces – A performance comparison of algorithms

open access: yesGeo-spatial Information Science, 2018
Finding the shortest path through open spaces is a well-known challenge for pedestrian routing engines. A common solution is routing on the open space boundary, which causes in most cases an unnecessarily long route. A possible alternative is to create a
Stefan Hahmann   +4 more
doaj   +1 more source

IMPROVED PUBLIC TRANSIT ROUTING ALGORITHM FOR FINDING THE SHORTEST K-PATH [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2018
Most of the existing public transit routing algorithms were developed on the basis of graph theory. Recently, algorithms are being developed that can compute for O-D public transit paths by using timetable information only, not using network structure ...
I. Jeon, H. Nam, C. Jun
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

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