Results 201 to 210 of about 344,150 (327)

Myocardial Recovery With Mechanical Circulatory Support Is Linked to Alternative Splicing and Subcellular Localization of CAMK2D. [PDF]

Circulation
Martin TG, Hunt DR, Ebmeier CC, Dhand AP, Alamana C, Cleveland JC, Graw SL, Bruner S, Bristow MR, Mestroni L, Taylor MRG, Burdick JA, Ambardekar AV, Buttrick PM, Leinwand LA.   +14 more
europepmc   +1 more source

Alternative splicing dynamics during human cardiac development in vivo and in vitro [PDF]

Beatriz Gomes-Silva, Marta Furtado, Marta Ribeiro, Sandra Martins, Teresa Carvalho, Henrike Maatz, Michael Gotthardt, Rosina Savisaar, Maria Carmo-Fonseca, Rosina Savisaar, Maria Carmo-Fonseca   +10 more
openalex   +1 more source

Additional file 7 of Alternative splicing landscapes in Arabidopsis thaliana across tissues and stress conditions highlight major functional differences with animals

, 2021
Guiomar Martín, Yamile Márquez, Federica Mantica, Paula Duque, Manuel Irimia   +4 more
openalex   +1 more source

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

Alternative splicing: from tumorigenesis to neoantigen-mediated cancer immunotherapy. [PDF]

Biomark Res
Lv YH, He YC, Dai XY, Yang XJ, Cai YS, Luo RH, Xie QY, Xie SN, Chen XT, Zhou QB, Wang J, Wu H, Lan T.   +12 more
europepmc   +1 more source

Emerging Roles of Activity-Dependent Alternative Splicing in Homeostatic Plasticity [PDF]

, 2020
Agnes Thalhammer, Fanny Jaudon, Lorenzo A. Cingolani   +2 more
openalex   +1 more source

Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development

Advanced Science, EarlyView.
Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu, Le Xie, Yuan Jin, Sen Chen, Xinyu Shi, Yanjun Zong, Zhengdong Zhao, Wei‐Jia Kong, Yu Sun   +8 more
wiley   +1 more source

Rna analysis of the regulation of expression and alternative splicing in polycystic ovarian syndrome. [PDF]

RNA Biol
Zhang Q, Zhu S, Jiang B.
europepmc   +1 more source

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

Advanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou, Xinying Lu, Ying Liu, Peiyu Yang, Shuo Sun, Yihua Liu, Yinyuan Mo, Guonian Zhu, Jae Seong Lee, Yirong Guo   +9 more
wiley   +1 more source

Predicting the structural impact of human alternative splicing. [PDF]

Genome Biol
Song Y, Zhang C, Omenn GS, O'Meara MJ, Welch JD.   +4 more
europepmc   +1 more source