Results 251 to 260 of about 336,398 (336)

Independent expression of the transforming amino-terminal domain of SV40 large I antigen from an alternatively spliced third SV40 early mRNA.

, 1993
Jens Zerrahn, Uwe Knippschild, Thomas Winkler, Wolfgang Deppert   +3 more
openalex   +1 more source

Site‐Specific Mitochondrial RNA N1‐Methyladenosine Demethylation via an Engineered MTS‐PUF‐ALKBH3 Fusion Protein

Advanced Science, EarlyView.
A CRISPR‐free mitochondrial RNA m1A demethylation (MRD) editor combining MTS, PUF proteins, and ALKBH3 enables precise m1A removal from mitochondrial mRNA and tRNA, which influences mitochondrial protein levels, cellular proliferation, ATP production, and mitochondrial respiration. Subsequently, in vivo demethylation of the m1A modification is achieved
Xiangrui Li, Deqiang Kong, Hongmei Liu, Jie Yang, Jiale Zhou, Yuqiang Qian, Ding Zhao, Jinze Li, Xinyu Wu, Tao Zhang, Xiaodi Sun, Yang Han, Liangxue Lai, Zhanjun Li   +13 more
wiley   +1 more source

MRAS: Master Regulator Analysis of Alternative Splicing. [PDF]

Adv Sci (Weinh)
Zhou L, Huang Y, Zhao Y, Guo D, Wen X, Xu R, Lv X, Wu S, Jing S, Liu Z.   +9 more
europepmc   +1 more source

Type II collagen mRNA containing an alternatively spliced exon predominates in the chick limb prior to chondrogenesis.

, 1991
Hyun‐Duck Nah, William B. Upholt
openalex   +1 more source

CDK4/6 Inhibitor Priming Enhances PD‐1 Blockade via Sellhi Neutrophil‐Induced Stat5a+ Progenitor Exhausted CD8+ T Cell

Advanced Science, EarlyView.
Activated tumor‐intrinsic cyclin D1‐CDK4/6 signaling attenuates lymphocyte infiltration, and consequently, and immunotherapy resistance in HNSCC. It is discovered that brief CDK4/6i priming before anti‐PD‐1 results in enhanced durability of ICB response durability through Stat5a+ progenitor exhausted CD8+ T cells induced by IL15‐secreted Sell(hi ...
Yu Zhang, Bao Sun, Rong Zhou, Zizhen Gong, Yong Han, Wenjie Tao, Chaoji Shi, Wuchang Zhang, Laikui Liu, Zhiyuan Zhang, Jiang Li, Qi Zhu, Weiwen Zhu, Ziyue Gu   +13 more
wiley   +1 more source

Nup93-Mediated RNA Alternative Splicing Associated With Diabetic Atherosclerosis. [PDF]

Mol Cell Proteomics
Yuan X, Zhang Q, Li J, Zhang Z, Ye S, Zhou W.   +5 more
europepmc   +1 more source

Snol, a novel alternatively spliced isoform of the ski protooncogene homolog, sno [PDF]

, 1993
Sonia Pearson‐White
openalex   +1 more source

Reprogramming Tumor‐Associated Macrophages via Targeted NAT10 Inhibition to Enhance Colorectal Cancer Immunotherapy

Advanced Science, EarlyView.
This study presents the sono‐sensitive nanorobot Sono@NAT10, which targets NAT10 condensates to reprogram tumor‐associated macrophages in colorectal cancer. By reducing the acetylation level of SRSF2 protein and activating HDAC10, Sono@NAT10 promotes M1 polarization, suppresses tumor progression, and strengthens immunotherapy. The approach demonstrates
Jiahao Zhu, Benjie Xu, Rui Hu, Bo Yang, Peipei Shen, Yu Xu, Xiaojun Zhang, Danqi Qian, Gang Wu, Shengjun Ji, Yutian Zhao, Ke Gu   +11 more
wiley   +1 more source

Systematic Analysis of Alternative Splicing in Transcriptomes of Multiple Sclerosis Patient Brain Samples. [PDF]

Int J Mol Sci
Sak M, Chariker JH, Rouchka EC.
europepmc   +1 more source

Alternative splicing of fructose 1,6-bisphosphate aldolase transcripts in Drosophila melanogaster predicts three isozymes.

, 1992
Rhonda L. Shaw-Lee, James L. Lissemore, David T. Sullivan, Dean R. Tolan   +3 more
openalex   +1 more source