This study investigates subgenome evolution and polyploidy in Cypriniformes fish, revealing complex phylogenetic relationships and genomic dynamics. By applying advanced subgenome partitioning methods, it uncovers novel insights into transposon activity and gene fractionation.
Yunyun Lv+14 more
wiley +1 more source
Deciphering alternative splicing patterns during cell fate transition of fast chemical reprogramming. [PDF]
Lu Y+8 more
europepmc +1 more source
Ubiquitin‐mediated selective autophagy plays a critical role in antiviral innate immunity. The study shows that upon RNA virus infection, cytoplasmic API5 undergoes SRPK1‐dependent phosphorylation at S464, which in turn suppresses p62 K141 ubiquitination‐dependent autophagy.
Tingjuan Deng+10 more
wiley +1 more source
Decoding Handwriting Trajectories from Intracortical Brain Signals for Brain‐to‐Text Communication
By developing a novel framework that optimizes both shape and temporal loss during decoder training, the authors successfully reconstruct human‐recognizable handwriting trajectories from intracortical neural signals for both Chinese characters and English letters, effectively resolving the temporal misalignment problem in clinical BCIs, thereby ...
Guangxiang Xu+6 more
wiley +1 more source
Alternative splicing of transposable elements in human breast cancer. [PDF]
Nesta A+4 more
europepmc +1 more source
Dysregulated RNA-binding proteins and alternative splicing: Emerging roles in autism spectrum disorder. [PDF]
Jeong J, Yoo HJ, An JY, Jeong S.
europepmc +1 more source
The maize transposable Ds1 element is alternatively spliced from exon sequences.
Susan R. Wessler
openalex +1 more source
YTHDC1 Is Essential for Postnatal Liver Development and Homeostasis
This study identifies YTHDC1 as a key regulator of postnatal liver development and disease. Hepatocyte‐specific deletion of Ythdc1 impairs hepatocyte maturation, causing liver injury, contributing to nonalcoholic steatohepatitis and hepatocellular carcinoma.
Xinzhi Li+8 more
wiley +1 more source
A novel MIR100HG transcript enhances tumorigenesis by inducing BCLAF1-mediated alternative splicing in colorectal cancer. [PDF]
Dai M+8 more
europepmc +1 more source
Single‐Droplet Dual‐Target Quantification of circRNA Biomarkers for Colorectal Cancer Screening
Circular RNAs are crucial in tumorigenesis. This study identifies circCK1γ3 and circWDR37 as dual plasma biomarkers for colorectal cancer (CRC) screening. It is developed Casµchip, a droplet microfluidic chip using Cas13a/b technology to quantify these biomarkers.
Jingsong Xu+11 more
wiley +1 more source