Results 201 to 210 of about 261,784 (335)

Alternatives to animal testing in basic and preclinical research of atopic dermatitis [PDF]

, 2018
Anna Löwa, Marijana Jevtić, Frida Gorreja, Sarah Hedtrich   +3 more
openalex   +1 more source

The alarming consequences of workforce reductions at the FDA, EPA, NIH and CDC in the United States. [PDF]

Arch Toxicol
Dietrich DR, von Aulock S, Bal-Price A, Coleman M, Cronin M, Jennings P, Mally A, Vinken M, Wright M, van den Berg M.   +9 more
europepmc   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source

Airborne toxicological assessment: The potential of lung-on-a-chip as an alternative to animal testing

, 2022
Ko-Chih Lin, Chien-Mei Yen, Jia‐Wei Yang, Johnson Chung, G.-Y. Chen   +4 more
openalex   +1 more source

In Silico Research Is Rewriting the Rules of Drug Development: Is It the End of Human Trials? [PDF]

Cureus
Lakhan SE.
europepmc   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

THE HEN'S EGG TEST - CHORIO-ALLANTOIC-MEMBRANE (HET -CAM) AND HAEMOLYSIS STUDY AS AN ALTERNATIVE TEST FOR OCCULAR IRRITANCY ANIMAL EXPERIMENTS (Draize Test) [PDF]

, 2018
Sadhana R Shahi Deepak G Wagh
openalex   +1 more source

"Lost in translation?" Animal research in the era of precision medicine. [PDF]

J Transl Med
Frühwein H, Paul NW.
europepmc   +1 more source

Alternatives to the use of animals in research, education and testing

ALTEX, 2016
Maryanne Wangari Kagai, Josphat Ngonyo, Samuel Macharia Theuri   +2 more
openaire   +3 more sources

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source