Results 71 to 80 of about 261,784 (335)
In November 2013, a group of international experts in animal research policy (n = 11) gathered in Vancouver, Canada, to discuss openness and accountability in animal research.
Elisabeth H. Ormandy+11 more
doaj +1 more source
Nutritional Immunomodulation as an Approach to Decreasing the Negative Effects of Stress in Poultry Production [PDF]
Stress can lead to changes in the immune response resulting in both increased and decreased resistance to opportunistic bacterial pathogens. Growth-promoting antibiotics have been a major tool in modulating hostpathogen interactions and limiting clinical
Huff, G. R., Huff, W. E., Rath, N. C.
core +1 more source
In silico methods – Computational alternatives to animal testing
A seminar and interactive workshop on “In silico Methods – Computational Alternatives to Animal Testing” was held in Berlin, Germany, organized by Annemarie Lang, Frank Butt- gereit and Andrea Volkamer at the Charite-Universitatsmedizin Berlin, on August 17-18, 2017. During the half-day seminar, the variety and applications of in silico methods as
Andrea Volkamer+9 more
openaire +4 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Vegetarians versus Vegans [PDF]
There is a gap in literature related to studies that explicitly compare vegetarians to vegans, as existing studies typically group these diets together and examine carnivorous and omnivorous diets in order to identify similarities and differences.
Kaplan, Hannah
core +1 more source
Meeting Report: Alternatives for Developmental Neurotoxicity Testing [PDF]
Developmental neurotoxicity testing (DNT) is perceived by many stakeholders to be an area in critical need of alternatives to current animal testing protocols and guidelines.
Alan Goldberg+4 more
core +2 more sources
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
Confronting the bias towards animal experimentation (animal methods bias)
Laws and policies are in place around the world to promote the replacement and reduction of nonhuman animals in science. These principles are rooted not just in ethical considerations for animals, but also in scientific considerations regarding the ...
Catharine E. Krebs+2 more
doaj +1 more source
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Alternatives to Animal Experimentation [PDF]
Alternatives to animal experimentation are highly touted today by animal welfare advocates. Their campaign for adopting alternatives has caused much discussion and debate within and outside the biomedical community.
Niemi, Steven M.
core +1 more source