Results 21 to 30 of about 338,965 (297)

Evaluation of physico-chemical and heavy metals status in irrigation, stagnant, and Indus River water at the trans-Himalayan region

open access: yesDiscover Water, 2023
The water quality of various resources is changing everywhere, including the high-altitude region, which may have adverse health effects on animals and the human population.
Guru Charan   +3 more
doaj   +1 more source

Comparison of Simulated High Altitude Pilot Effective Performance Time Between Habitual Smokers and Non-Smokers [PDF]

open access: yes, 2003
Smoking attenuates the amount of oxygen that diffuses from the lung tissue and oxygenates the blood (Guyton, 1996). High altitudes attenuate the oxygen available for transport to the blood.
James F. Fletcher, Fletcher, James F.
core   +1 more source

Targeting JUN, CEBPB, and HDAC3: A Novel Strategy to Overcome Drug Resistance in Hypoxic Glioblastoma

open access: yesFrontiers in Oncology, 2019
Hypoxia is a predominant feature in glioblastoma (GBM) and contributes greatly to its drug resistance. However, the molecular mechanisms which are responsible for the development of the resistant phenotype of GBM under hypoxic conditions remain unclear ...
Yixing Gao   +21 more
doaj   +1 more source

Exercise and altitude [PDF]

open access: yesPostgraduate Medical Journal, 1979
Summary In studies concerned with the performance at high altitude it is often not possible to separate the effects which are due to hypoxia from those associated with the stress of ascent. Some of the basic observations concerning exercise at high altitude are reviewed and a study is described which was designed to simulate the physical
openaire   +2 more sources

Wide distribution and altitude correlation of an archaic high-altitude-adaptive EPAS1 haplotype in the Himalayas.

open access: yes, 2016
High-altitude adaptation in Tibetans is influenced by introgression of a 32.7-kb haplotype from the Denisovans, an extinct branch of archaic humans, lying within the endothelial PAS domain protein 1 (EPAS1), and has also been reported in Sherpa.
S. Hackinger (7627076)   +9 more
core   +6 more sources

IL-6/STAT3 Induced Neuron Apoptosis in Hypoxia by Downregulating ATF6 Expression

open access: yesFrontiers in Physiology, 2021
Background: Neuron apoptosis, regulated by endoplasmic reticulum (ER) stress in the hippocampus, is an essential factor influencing the cognitive impairment induced by hypobaric hypoxia.
Simin Zhou   +26 more
doaj   +1 more source

Stratospheric Optical Inter-Platform Links for High Altitude Platforms [PDF]

open access: yes, 2002
Optical propagation simulations for the case of a laser optical link between two stratospheric High Altitude Platforms have been performed. The simulations, together with communications link budget calculations, show that high data rate communications ...
Giggenbach, Dirk   +7 more
core   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp   +4 more
wiley   +1 more source

Advancing high-altitude medicine: a model for the future

open access: yesSignal Transduction and Targeted Therapy
With rising global high-altitude travel, occupational exposure, and permanent habitation, the health burden of high-altitude-specific diseases and high-altitude-related diseases has become increasingly prominent, highlighting an urgent need for in-depth ...
Wenjin Sun   +6 more
doaj   +1 more source

Identification of a miRNA–mRNA Regulatory Networks in Placental Tissue Associated With Tibetan High Altitude Adaptation

open access: yesFrontiers in Genetics, 2021
The Tibetan population has lived and successfully reproduced at high altitude for many generations. Studies have shown that Tibetans have various mechanisms for protection against high-altitude hypoxia, which are probably due, at least in part, to ...
Noryung Tenzing   +22 more
doaj   +1 more source

Home - About - Disclaimer - Privacy